HK1205744A1 - Identification of channelrhodopsin-2 (chop2) mutations and methods of use -2(chop2) - Google Patents

Identification of channelrhodopsin-2 (chop2) mutations and methods of use -2(chop2)

Info

Publication number
HK1205744A1
HK1205744A1 HK15106172.0A HK15106172A HK1205744A1 HK 1205744 A1 HK1205744 A1 HK 1205744A1 HK 15106172 A HK15106172 A HK 15106172A HK 1205744 A1 HK1205744 A1 HK 1205744A1
Authority
HK
Hong Kong
Prior art keywords
chop2
channelrhodopsin
mutations
identification
methods
Prior art date
Application number
HK15106172.0A
Other languages
English (en)
Chinese (zh)
Inventor
Zhuo-Hua Pan
Original Assignee
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State filed Critical Univ Wayne State
Publication of HK1205744A1 publication Critical patent/HK1205744A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK15106172.0A 2012-03-05 2015-06-29 Identification of channelrhodopsin-2 (chop2) mutations and methods of use -2(chop2) HK1205744A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261606663P 2012-03-05 2012-03-05
PCT/US2013/029171 WO2013134295A1 (en) 2012-03-05 2013-03-05 Identification of channelrhodopsin-2 (chop2) mutations and methods of use

Publications (1)

Publication Number Publication Date
HK1205744A1 true HK1205744A1 (en) 2015-12-24

Family

ID=47892055

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15106172.0A HK1205744A1 (en) 2012-03-05 2015-06-29 Identification of channelrhodopsin-2 (chop2) mutations and methods of use -2(chop2)

Country Status (17)

Country Link
US (2) US10947281B2 (es)
EP (1) EP2822964B1 (es)
JP (3) JP6395611B2 (es)
KR (1) KR102137717B1 (es)
CN (2) CN104334575A (es)
AU (4) AU2013230112A1 (es)
CA (1) CA2866405A1 (es)
DK (1) DK2822964T3 (es)
EA (1) EA201491643A1 (es)
ES (1) ES2703324T3 (es)
HK (1) HK1205744A1 (es)
HU (1) HUE040487T2 (es)
MX (1) MX360085B (es)
NZ (1) NZ629843A (es)
PL (1) PL2822964T3 (es)
PT (1) PT2822964T (es)
WO (1) WO2013134295A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101484005A (zh) 2006-05-04 2009-07-15 韦恩州立大学 通过向体内递送视紫红质核酸恢复视觉响应
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
ES2703324T3 (es) 2012-03-05 2019-03-08 Univ Wayne State Identificación de mutaciones de canalrodopsina-2 (Chop2) y métodos de uso
AU2014243925B2 (en) 2013-03-14 2018-12-06 Wayne State University Method of enhancing delivery of therapeutic compounds to the eye
US10234761B2 (en) 2013-07-08 2019-03-19 Basf Se Oxime ester photoinitiators
EP3117002A1 (en) 2014-03-11 2017-01-18 Wayne State University A modified mglur6 promoter and methods of use
CA3022634A1 (en) 2016-05-03 2017-11-09 Wayne State University Method of enhancing viral-mediated gene delivery in the eye using proteosome inhibitors
WO2017207745A1 (en) * 2016-06-03 2017-12-07 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Mutant light-inducible ion channel of channelrhodopsin
KR20230169427A (ko) * 2016-08-29 2023-12-15 웨인 스테이트 유니버시티 개선된 광 민감성을 갖는 채널옵신 변이체에서의 돌연변이의 확인 및 이의 용도
CN110267972A (zh) * 2016-11-06 2019-09-20 纳秒示波器科技有限公司 由多特征视蛋白进行的用于视力恢复的光学调制以及其其他应用
CN111032068A (zh) * 2017-04-12 2020-04-17 马克斯·普朗克科学促进学会 新的光遗传学工具
SG11202004940VA (en) * 2017-12-04 2020-06-29 Salvat Lab Sa Ophthalmic topical composition comprising dobesilic acid for treating diseases of the posterior segment of the eye
JP6567153B1 (ja) * 2018-09-28 2019-08-28 学校法人東北工業大学 対象化合物の特性の予測を行うための方法、コンピュータシステム、プログラム

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4498919A (en) 1983-10-31 1985-02-12 Corning Glass Works Method for making colored photochromic prescription ophthalmic lenses
US6610287B1 (en) 1990-04-16 2003-08-26 The General Hospital Corporation Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
US5827702A (en) 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
AU7467598A (en) 1997-04-21 1998-11-13 University Of Florida Materials and methods for treatment of retinal diseases
NZ511037A (en) 1998-09-17 2005-02-25 Univ Florida Methods for treatment of degenerative retinal diseases
CA2406743A1 (en) 2000-04-28 2001-11-08 The Trustees Of The University Of Pennsylvania Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
CA2442670A1 (en) 2001-04-13 2002-10-24 The Trustees Of The University Of Pennsylvania Method of treating or retarding the development of blindness
AU2002323210A1 (en) 2001-08-16 2003-03-03 Sloan Kettering Institute For Cancer Research Bio-synthetic photostimulators and methods of use
DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
WO2004009022A2 (en) 2002-07-18 2004-01-29 The General Hospital Corp. Method for augmenting vision in persons suffering from photoreceptor cell degeneration
US7186699B2 (en) 2003-06-03 2007-03-06 Cell Genesys, Inc. Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes
JP2007527738A (ja) 2003-11-05 2007-10-04 ニューロヴィジョン, インコーポレイテッド 視覚を改善するための方法および装置
US8906360B2 (en) 2005-07-22 2014-12-09 The Board Of Trustees Of The Leland Stanford Junior University Light-activated cation channel and uses thereof
CN101484005A (zh) 2006-05-04 2009-07-15 韦恩州立大学 通过向体内递送视紫红质核酸恢复视觉响应
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
EP2614079B1 (en) 2010-09-08 2015-07-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Mutant channelrhodopsin 2
ES2703324T3 (es) 2012-03-05 2019-03-08 Univ Wayne State Identificación de mutaciones de canalrodopsina-2 (Chop2) y métodos de uso
KR101639859B1 (ko) * 2014-03-06 2016-07-14 포항공과대학교 산학협력단 광 자극에 의한 미토콘드리아 활성의 시공간적 가역 조절 방법

Also Published As

Publication number Publication date
AU2013230112A1 (en) 2014-09-25
CA2866405A1 (en) 2013-09-12
CN104334575A (zh) 2015-02-04
MX360085B (es) 2018-10-10
WO2013134295A1 (en) 2013-09-12
EA201491643A1 (ru) 2015-02-27
US20150044181A1 (en) 2015-02-12
AU2021245195A1 (en) 2021-11-04
KR102137717B1 (ko) 2020-07-27
JP6395611B2 (ja) 2018-09-26
AU2019216638B2 (en) 2021-07-08
AU2019216638A1 (en) 2019-09-05
NZ629843A (en) 2017-03-31
NZ727041A (en) 2022-01-28
AU2017239601B2 (en) 2019-05-16
JP2019193656A (ja) 2019-11-07
AU2021245195B2 (en) 2023-09-28
PT2822964T (pt) 2018-11-29
JP2015510759A (ja) 2015-04-13
CN111378020A (zh) 2020-07-07
US20220033449A1 (en) 2022-02-03
ES2703324T3 (es) 2019-03-08
MX2014010664A (es) 2015-03-06
EP2822964A1 (en) 2015-01-14
HUE040487T2 (hu) 2019-03-28
KR20140132401A (ko) 2014-11-17
PL2822964T3 (pl) 2019-05-31
EP2822964B1 (en) 2018-08-22
US10947281B2 (en) 2021-03-16
AU2017239601A1 (en) 2017-10-26
JP2018134098A (ja) 2018-08-30
DK2822964T3 (en) 2018-12-10

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