HK1205467A1 - Pharmaceutical composition for the prophylaxis and treatment of psychological, behavioral and cognitive disorders - Google Patents
Pharmaceutical composition for the prophylaxis and treatment of psychological, behavioral and cognitive disordersInfo
- Publication number
- HK1205467A1 HK1205467A1 HK15106114.1A HK15106114A HK1205467A1 HK 1205467 A1 HK1205467 A1 HK 1205467A1 HK 15106114 A HK15106114 A HK 15106114A HK 1205467 A1 HK1205467 A1 HK 1205467A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- psychological
- behavioral
- prophylaxis
- treatment
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2012121410/15A RU2488388C1 (ru) | 2012-05-24 | 2012-05-24 | Фармацевтическая композиция для профилактики и лечения психических, поведенческих, когнитивных расстройств |
| PCT/RU2012/000888 WO2013176567A1 (ru) | 2012-05-24 | 2012-10-31 | Фармацевтическая композиция для профилактики и лечения психических, поведенческих, когнитивных расстройств |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1205467A1 true HK1205467A1 (en) | 2015-12-18 |
Family
ID=49155569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15106114.1A HK1205467A1 (en) | 2012-05-24 | 2015-06-26 | Pharmaceutical composition for the prophylaxis and treatment of psychological, behavioral and cognitive disorders |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20150157604A1 (ru) |
| EP (1) | EP2857011A4 (ru) |
| JP (1) | JP5864819B2 (ru) |
| KR (1) | KR101581611B1 (ru) |
| CN (1) | CN104334166A (ru) |
| AU (1) | AU2012380583B2 (ru) |
| CA (1) | CA2873891C (ru) |
| EA (1) | EA201400973A1 (ru) |
| HK (1) | HK1205467A1 (ru) |
| IL (1) | IL235852A0 (ru) |
| IN (1) | IN2014DN09940A (ru) |
| RU (1) | RU2488388C1 (ru) |
| UA (1) | UA112352C2 (ru) |
| WO (1) | WO2013176567A1 (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2536270C1 (ru) * | 2013-10-21 | 2014-12-20 | Общество с ограниченной ответственностью ООО "ВАЛЕНТА ИНТЕЛЛЕКТ" | Комбинация для коррекции неврологического и психоэмоционального статуса при органических нарушениях цнс |
| RU2623865C1 (ru) * | 2016-06-29 | 2017-06-29 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция, содержащая комбинацию мемантина и мелатонина |
| CA3029382C (en) * | 2016-06-29 | 2021-10-12 | Ltd "Valenta-Intellekt" | Pharmaceutical composition containing combination of memantine and melatonin |
| RU2654713C1 (ru) * | 2016-06-29 | 2018-05-22 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция, содержащая комбинацию мемантина и мелатонина |
| US10849856B2 (en) | 2016-10-31 | 2020-12-01 | Neurim Pharmaceuticals Ltd. | Melatonin mini-tablets and method of manufacturing the same |
| CN109922795B (zh) | 2016-10-31 | 2021-10-08 | 纽里姆药物有限公司 | 褪黑素小片剂及其制备方法 |
| CA3078704A1 (en) | 2017-10-10 | 2019-04-18 | Massachusetts Institute Of Technology | Systems and methods for preventing, mitigating, and/or treating dementia |
| US10960225B2 (en) * | 2017-10-10 | 2021-03-30 | Massachusetts Institute Of Technology | Systems and methods for preventing, mitigating, and/or treating dementia via visual stimulation that binds higher order brain regions, reduces neurodegeneration and neuroinflammation, and improves cognitive function |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES413944A1 (es) | 1972-04-20 | 1976-06-01 | Merz & Co | Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5. |
| DE2856393C2 (de) | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
| ATE94384T1 (de) | 1989-04-14 | 1993-10-15 | Merz & Co Gmbh & Co | Verwendung von adamantan-derivaten zur praevention und behandlung der cerebralen ischaemie. |
| US5614560A (en) | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| US6469044B1 (en) | 1995-02-01 | 2002-10-22 | Neurim Pharmaceuticals (1991) Ltd. | Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies |
| PL193237B1 (pl) * | 1997-06-30 | 2007-01-31 | Merz Pharma Gmbh & Co Kgaa | Pochodne 1-aminoalkilocykloheksanu, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie |
| US20040122090A1 (en) * | 2001-12-07 | 2004-06-24 | Lipton Stuart A. | Methods for treating neuropsychiatric disorders with nmda receptor antagonists |
| US20050129783A1 (en) * | 2001-04-19 | 2005-06-16 | Mccleary Edward L. | Composition and method for treatment of neurophysiological conditions and maintenance of neurophysiological health |
| US7183321B2 (en) * | 2001-12-17 | 2007-02-27 | Bristol-Myers Squibb Company | Antidiabetic formulation and method |
| PT1562585E (pt) | 2002-10-30 | 2011-02-23 | Asat Ag Applied Science & Tech | Unidades de dosagem diária de melatonina |
| RU2268737C2 (ru) | 2004-02-16 | 2006-01-27 | Государственное учреждение институт клинической иммунологии СО РАМН | Способ лечения атопического дерматита |
| EP1781261A1 (en) * | 2004-06-17 | 2007-05-09 | Forest Laboratories, Inc. | Modified release formulation of memantine |
| JP2008504372A (ja) * | 2004-06-18 | 2008-02-14 | ニューロケム （インターナショナル） リミティッド | β−アミロイド関連疾患の治療のための治療用製剤 |
| US20060079582A1 (en) * | 2004-09-23 | 2006-04-13 | Jeffrey Jonas | Memantine for the treatment of childhood behavioral disorders |
| MY148806A (en) * | 2005-04-04 | 2013-05-31 | Takeda Pharmaceutical | Prophylactic or therapeutic agent for nocturnal conduct disorder associated with dementia |
| CN1709230A (zh) * | 2005-07-05 | 2005-12-21 | 北京阜康仁生物制药科技有限公司 | 盐酸美金刚分散片及其制备方法 |
| RU2294741C1 (ru) | 2005-08-08 | 2007-03-10 | Рина Михайловна Заславская | Способ лечения больных ишемической болезнью сердца, стабильной стенокардией в сочетании с артериальной гипертонией |
| RU2445973C2 (ru) * | 2006-05-22 | 2012-03-27 | Ванда Фармасьютиклз, Инк. | Способ лечения глубокой депрессии у человека |
| KR20090029200A (ko) * | 2006-05-22 | 2009-03-20 | 반다 파마슈티칼즈, 인코퍼레이티드. | 우울증 질환에 대한 치료 |
| CN101528202A (zh) * | 2006-07-05 | 2009-09-09 | 特瓦制药工业有限公司 | 美金刚的药物组合物 |
| EP2040676A2 (en) * | 2006-07-06 | 2009-04-01 | Forest Laboratories, Inc. | Orally dissolving formulations of memantine |
| GB0623897D0 (en) * | 2006-11-30 | 2007-01-10 | Pliva Istrazivanje I Razvoj D | Pharmaceutical composition of memantine |
| US20080167363A1 (en) * | 2006-12-28 | 2008-07-10 | Braincells, Inc | Modulation of Neurogenesis By Melatoninergic Agents |
| RU2326660C1 (ru) | 2007-03-14 | 2008-06-20 | Закрытое акционерное общество "Биологические исследования и системы" | Пероральный лекарственный препарат мемантин (варианты) и способ его получения (варианты) |
| CA2683436C (en) | 2007-04-11 | 2016-07-26 | John A. Mccarty | Melatonin tablet and methods of preparation and use |
| WO2008128095A1 (en) | 2007-04-12 | 2008-10-23 | Regents Of The University Of Minnesota | Ischemia/reperfusion protection compositions and methods of using |
| US20100256184A1 (en) * | 2008-08-13 | 2010-10-07 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| AU2010211220B2 (en) * | 2009-02-06 | 2013-08-01 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
| RU2394571C1 (ru) | 2009-05-14 | 2010-07-20 | Государственное бюджетное учреждение здравоохранения города Москвы "Городская клиническая больница № 24" Департамента здравоохранения города Москвы | Способ лечения воспалительных заболеваний кишечника |
| RU2418586C2 (ru) | 2009-06-11 | 2011-05-20 | Государственное образовательное учреждение высшего профессионального образования "Новосибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО НГМУ Росздрава) | Способ коррекции нарушений в репродуктивных органах, вызванных высокой температурой |
| RU2428183C1 (ru) | 2010-07-01 | 2011-09-10 | Рина Михайловна Заславская | Адаптоген для метеочувствительных больных стенокардией и артериальной гипертензией и применение мелатонина в качестве адаптогена |
-
2012
- 2012-05-24 RU RU2012121410/15A patent/RU2488388C1/ru not_active IP Right Cessation
- 2012-10-31 IN IN9940DEN2014 patent/IN2014DN09940A/en unknown
- 2012-10-31 JP JP2015513964A patent/JP5864819B2/ja not_active Expired - Fee Related
- 2012-10-31 US US14/400,526 patent/US20150157604A1/en not_active Abandoned
- 2012-10-31 CA CA2873891A patent/CA2873891C/en not_active Expired - Fee Related
- 2012-10-31 KR KR1020147032836A patent/KR101581611B1/ko active IP Right Grant
- 2012-10-31 EP EP12877152.4A patent/EP2857011A4/en not_active Withdrawn
- 2012-10-31 UA UAA201412436A patent/UA112352C2/uk unknown
- 2012-10-31 EA EA201400973A patent/EA201400973A1/ru unknown
- 2012-10-31 AU AU2012380583A patent/AU2012380583B2/en not_active Revoked
- 2012-10-31 CN CN201280073167.XA patent/CN104334166A/zh not_active Withdrawn
- 2012-10-31 WO PCT/RU2012/000888 patent/WO2013176567A1/ru active Application Filing
-
2014
- 2014-11-23 IL IL235852A patent/IL235852A0/en unknown
-
2015
- 2015-06-26 HK HK15106114.1A patent/HK1205467A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150005999A (ko) | 2015-01-15 |
| AU2012380583B2 (en) | 2015-01-22 |
| EP2857011A1 (en) | 2015-04-08 |
| CN104334166A (zh) | 2015-02-04 |
| JP2015517569A (ja) | 2015-06-22 |
| AU2012380583A1 (en) | 2014-12-18 |
| EA201400973A1 (ru) | 2015-02-27 |
| UA112352C2 (uk) | 2016-08-25 |
| WO2013176567A1 (ru) | 2013-11-28 |
| RU2488388C1 (ru) | 2013-07-27 |
| EP2857011A4 (en) | 2015-12-02 |
| CA2873891A1 (en) | 2013-11-28 |
| IN2014DN09940A (ru) | 2015-08-14 |
| JP5864819B2 (ja) | 2016-02-17 |
| US20150157604A1 (en) | 2015-06-11 |
| IL235852A0 (en) | 2015-01-29 |
| CA2873891C (en) | 2016-02-16 |
| KR101581611B1 (ko) | 2015-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL256624B (en) | Pharmaceutical compounds and preparations thereof for the treatment of inflammatory disorders | |
| IL236221A (en) | History of theophyridone and pharmacological preparations containing them for the treatment of diseases | |
| EP2827856A4 (en) | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF MUSCLE DISEASES | |
| HK1210968A1 (en) | Compositions and treatment for eye diseases and disorders | |
| HK1205467A1 (en) | Pharmaceutical composition for the prophylaxis and treatment of psychological, behavioral and cognitive disorders | |
| EP2931268A4 (en) | GAMMA HYDROXYBUTYRATE COMPOSITIONS AND USE FOR THE TREATMENT OF DISORDERS | |
| HK1220324A1 (zh) | 用於治療血管緊張素相關疾病的方法、化合物和組合物 | |
| HK1207860A1 (en) | 2-phenyl-5-heterocyclyl-tetrahydro-2h-pyran-3-amine compounds for use in the treatment of diabetes and its associated disorders 2--5---2h--3- | |
| HK1207593A1 (en) | Medicament for treating mental and behavioural disorders | |
| HK1216641A1 (zh) | 用於治療σ受體相關疾病和病症的 -三唑- -胺 | |
| PT2859896T (pt) | Composições farmacêuticas para o tratamento de distúrbios musculares | |
| HK1197235A1 (zh) | 二氫吡唑、其藥物組合物及其治療生育障礙的用途 | |
| RS54961B1 (sr) | Farmaceutska kompozicija za lečenje promuklosti ili bolova u grlu | |
| ZA201408060B (en) | Compositions and methods for the treatment of neurological disorders | |
| IL235272B (en) | Alfentanil composition for the treatment of acute pain | |
| IL234093A0 (en) | Preparations and dosages for oral administration and their uses for the treatment of Gaucher's disease | |
| ZA201408061B (en) | Compositions and methods for the treatment of neurological disorders | |
| GB201315072D0 (en) | Novel compounds and pharmaceutical compositions thereoffor the treatment of proliferative disorders | |
| HK1210967A1 (en) | Combination for the prophylaxis and treatment of behavioural, mental and cognitive disorders | |
| HUP1300454A2 (hu) | Daganatos betegségek gyógyítására és megelõzésére alkalmas gyógyászati készítmények, és eljárás azok elõállítására | |
| AU2013901514A0 (en) | Formulation and methods for treatment of mental disorders | |
| SI2812351T1 (sl) | Farmacevtski sestavek za zdravljenje multiple skleroze |