HK1205186A1 - Method for the expression of polypeptides using modified nucleic acids - Google Patents

Method for the expression of polypeptides using modified nucleic acids

Info

Publication number
HK1205186A1
HK1205186A1 HK15105668.3A HK15105668A HK1205186A1 HK 1205186 A1 HK1205186 A1 HK 1205186A1 HK 15105668 A HK15105668 A HK 15105668A HK 1205186 A1 HK1205186 A1 HK 1205186A1
Authority
HK
Hong Kong
Prior art keywords
polypeptides
expression
nucleic acids
modified nucleic
modified
Prior art date
Application number
HK15105668.3A
Other languages
English (en)
Chinese (zh)
Inventor
Stefan Klostermann
Erhard Kopetzki
Ursula Schwarz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48184161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1205186(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1205186A1 publication Critical patent/HK1205186A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
HK15105668.3A 2012-04-17 2015-06-16 Method for the expression of polypeptides using modified nucleic acids HK1205186A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12164430 2012-04-17
PCT/EP2013/057808 WO2013156443A1 (fr) 2012-04-17 2013-04-15 Procédé d'expression de polypeptides faisant appel à des acides nucléiques modifiés

Publications (1)

Publication Number Publication Date
HK1205186A1 true HK1205186A1 (en) 2015-12-11

Family

ID=48184161

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105668.3A HK1205186A1 (en) 2012-04-17 2015-06-16 Method for the expression of polypeptides using modified nucleic acids

Country Status (12)

Country Link
US (2) US20150246961A1 (fr)
EP (2) EP2839011B1 (fr)
JP (2) JP6224077B2 (fr)
KR (1) KR102064025B1 (fr)
CN (2) CN114107352A (fr)
BR (1) BR112014025693B1 (fr)
CA (1) CA2865676C (fr)
ES (1) ES2599386T3 (fr)
HK (1) HK1205186A1 (fr)
MX (1) MX349596B (fr)
RU (1) RU2014144881A (fr)
WO (1) WO2013156443A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013156443A1 (fr) 2012-04-17 2013-10-24 F. Hoffmann-La Roche Ag Procédé d'expression de polypeptides faisant appel à des acides nucléiques modifiés
EP3027743A1 (fr) 2013-07-29 2016-06-08 Danisco US Inc. Variants enzymatiques
BR112020023411A2 (pt) * 2018-05-29 2021-03-09 Firmenich S/A Método para produzir compostos de albicanol
EP3810770A1 (fr) * 2018-08-20 2021-04-28 Ucl Business Ltd Nucléotides codant pour le facteur ix
JP7511591B2 (ja) * 2019-06-28 2024-07-05 エフ． ホフマン－ラ ロシュ アーゲー 抗体の製造方法
CN114774391B (zh) * 2022-03-09 2023-03-14 华南农业大学 一种抗大肠杆菌的噬菌体内溶素及其应用
CN114507682A (zh) * 2022-03-16 2022-05-17 华南农业大学 编码重组NlpC/P60内肽酶蛋白的基因及其应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5010182A (en) 1987-07-28 1991-04-23 Chiron Corporation DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides
AU4005289A (en) 1988-08-25 1990-03-01 Smithkline Beecham Corporation Recombinant saccharomyces
US5082767A (en) 1989-02-27 1992-01-21 Hatfield G Wesley Codon pair utilization
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
DK0628639T3 (da) 1991-04-25 2000-01-24 Chugai Pharmaceutical Co Ltd Rekonstitueret humant antistof mod human interleukin-6-receptor
US7018809B1 (en) 1991-09-19 2006-03-28 Genentech, Inc. Expression of functional antibody fragments
US5795737A (en) 1994-09-19 1998-08-18 The General Hospital Corporation High level expression of proteins
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5840523A (en) 1995-03-01 1998-11-24 Genetech, Inc. Methods and compositions for secretion of heterologous polypeptides
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
EP0972838B1 (fr) 1998-07-15 2004-09-15 Roche Diagnostics GmbH Système de sélection par complémentation d' une auxotrophie en absence d'antibiotique chez E. coli
US6291245B1 (en) 1998-07-15 2001-09-18 Roche Diagnostics Gmbh Host-vector system
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
NZ517906A (en) 1999-10-04 2003-01-31 Medicago Inc Cloning of genomic sequences encoding nitrite reductase (NiR) for use in regulated expression of foreign genes in host plants
EP1156112B1 (fr) 2000-05-18 2006-03-01 Geneart GmbH Gènes synthétiques pour gagpol et leur utilisation
GB0014288D0 (en) * 2000-06-10 2000-08-02 Smithkline Beecham Biolog Vaccine
DE10037111A1 (de) * 2000-07-27 2002-02-07 Boehringer Ingelheim Int Herstellung eines rekombinanten Proteins in einer prokaryontischen Wirtszelle
AU2002254357A1 (en) * 2001-03-22 2002-10-08 Dendreon Corporation Nucleic acid molecules encoding serine protease cvsp14, the encoded polypeptides and methods based thereon
WO2003070957A2 (fr) 2002-02-20 2003-08-28 Novozymes A/S Production de polypeptides de plantes
EP1490494A1 (fr) 2002-04-01 2004-12-29 Walter Reed Army Institute of Research Procede pour concevoir des sequences d'acides nucleiques de synthese pour l'expression optimale de proteines dans une cellule hote
US7432342B2 (en) * 2002-05-03 2008-10-07 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof and related documents
CA2443365C (fr) 2002-11-19 2010-01-12 F. Hoffmann-La Roche Ag Methodes de production par recombinaison de peptides antifusiogenes
GB0308988D0 (en) * 2003-04-17 2003-05-28 Univ Singapore Molecule
JP4228072B2 (ja) * 2003-06-04 2009-02-25 独立行政法人農業・食品産業技術総合研究機構 アビジンをコードする人工合成遺伝子
JP5331340B2 (ja) 2004-05-18 2013-10-30 バイカル インコーポレイテッド インフルエンザウィルスワクチン組成物、及びその使用方法
WO2007142954A2 (fr) 2006-05-30 2007-12-13 Dow Global Technologies Inc. Procédé d'optimisation d'un codon
CN101627053A (zh) * 2006-06-12 2010-01-13 西福根有限公司 泛细胞表面受体特异的治疗剂
WO2008000632A1 (fr) 2006-06-29 2008-01-03 Dsm Ip Assets B.V. Procédé pour obtenir une expression de polypeptides améliorée
WO2013156443A1 (fr) * 2012-04-17 2013-10-24 F. Hoffmann-La Roche Ag Procédé d'expression de polypeptides faisant appel à des acides nucléiques modifiés

Also Published As

Publication number Publication date
BR112014025693A2 (pt) 2018-08-07
EP2839011A1 (fr) 2015-02-25
EP2839011B1 (fr) 2016-09-14
MX349596B (es) 2017-08-04
CN114107352A (zh) 2022-03-01
ES2599386T3 (es) 2017-02-01
JP6224077B2 (ja) 2017-11-01
WO2013156443A1 (fr) 2013-10-24
CA2865676A1 (fr) 2013-10-24
MX2014011805A (es) 2014-12-08
US20150246961A1 (en) 2015-09-03
EP3138917A1 (fr) 2017-03-08
KR102064025B1 (ko) 2020-01-08
BR112014025693B1 (pt) 2021-12-07
KR20140146105A (ko) 2014-12-24
US20180100006A1 (en) 2018-04-12
JP2018038408A (ja) 2018-03-15
JP2015514406A (ja) 2015-05-21
RU2014144881A (ru) 2016-06-10
CN104245937B (zh) 2021-09-21
CN104245937A (zh) 2014-12-24
CA2865676C (fr) 2020-03-10
EP3138917B2 (fr) 2024-10-23
EP3138917B1 (fr) 2019-08-21

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