HK1204988A1 - Methods and compositions for preventing or treating ophthalmic conditions - Google Patents

Methods and compositions for preventing or treating ophthalmic conditions

Info

Publication number
HK1204988A1
HK1204988A1 HK15105911.8A HK15105911A HK1204988A1 HK 1204988 A1 HK1204988 A1 HK 1204988A1 HK 15105911 A HK15105911 A HK 15105911A HK 1204988 A1 HK1204988 A1 HK 1204988A1
Authority
HK
Hong Kong
Prior art keywords
compositions
preventing
methods
ophthalmic conditions
treating ophthalmic
Prior art date
Application number
HK15105911.8A
Other languages
English (en)
Chinese (zh)
Inventor
Wilson D Travis
Mooney K George
Peter J Oates
Original Assignee
Stealth Peptides Internat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stealth Peptides Internat Inc filed Critical Stealth Peptides Internat Inc
Publication of HK1204988A1 publication Critical patent/HK1204988A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK15105911.8A 2012-02-22 2015-06-22 Methods and compositions for preventing or treating ophthalmic conditions HK1204988A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261601878P 2012-02-22 2012-02-22
US201261605576P 2012-03-01 2012-03-01
PCT/US2013/027175 WO2013126597A1 (en) 2012-02-22 2013-02-21 Methods and compositions for preventing or treating ophthalmic conditions

Publications (1)

Publication Number Publication Date
HK1204988A1 true HK1204988A1 (en) 2015-12-11

Family

ID=49006208

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105911.8A HK1204988A1 (en) 2012-02-22 2015-06-22 Methods and compositions for preventing or treating ophthalmic conditions

Country Status (8)

Country Link
US (3) US20150018288A1 (ja)
EP (4) EP2817018A4 (ja)
JP (3) JP2015509500A (ja)
CN (2) CN104244964A (ja)
AU (3) AU2013222423A1 (ja)
CA (1) CA2865317A1 (ja)
HK (1) HK1204988A1 (ja)
WO (1) WO2013126597A1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2750258T3 (es) 2013-03-01 2020-03-25 Stealth Biotherapeutics Corp Métodos y composiciones para la prevención o tratamiento del síndrome de Barth
CN116440247A (zh) * 2013-03-01 2023-07-18 康德生物医疗有限公司 治疗线粒体疾病的方法
US10047395B2 (en) 2013-06-26 2018-08-14 Stealth Biotherapeutics Corp Methods and compositions for detecting and diagnosing diseases and conditions
WO2015017781A1 (en) * 2013-08-01 2015-02-05 Stealth Peptides International, Inc. Methods and compositions for preventing or treating leber's hereditary optic neuropathy
CN112457368A (zh) 2013-12-27 2021-03-09 康德生物医疗技术公司 药学相关的芳香族阳离子肽
US20160317606A1 (en) * 2014-01-06 2016-11-03 Stealth Bio Therapeutics Corp Methods and compositions for preventing or treating dominant optic atrophy
JP2017512762A (ja) * 2014-03-03 2017-05-25 ステルス バイオセラピューティックス コープ 薬学的に妥当な芳香族カチオン性ペプチド及びその生成方法
JP6526066B2 (ja) * 2014-03-03 2019-06-05 アンコール・ヴィジョン・インコーポレイテッド リポ酸コリンエステル組成物及び使用方法
JP6854771B2 (ja) 2015-03-06 2021-04-07 ステルス バイオセラピューティックス コープ 薬学的に適切なペプチドを調製するための方法
CN115160402A (zh) 2016-03-11 2022-10-11 隐形生物治疗公司 结晶盐形式
EP3442990A4 (en) 2016-04-11 2019-12-18 Carnot, LLC CHIRAL PEPTIDES
US11034724B2 (en) 2017-04-05 2021-06-15 Stealth Biotherapeutics Corp. Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
CA3129423A1 (en) * 2019-02-08 2020-08-13 Ohio State Innovation Foundation Drug delivery compositions for ocular administration of therapeutics and methods of use thereof
EP3771467A1 (en) * 2019-07-30 2021-02-03 Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau Ss-31 for the prevention and/or treatment of aneurysm
KR102429281B1 (ko) * 2020-05-25 2022-08-05 (주)노바셀테크놀로지 신규 안구건조증 치료용 약학적 조성물
US20240209038A1 (en) * 2021-07-01 2024-06-27 The Regents Of The University Of California Targeting piezo1 to treat inherited and age-related macular degenerations
CN113975402B (zh) * 2021-07-19 2023-05-16 河南大学 靶向脑缺血区线粒体的神经保护药物ss31-ha-qt及其荧光探针和应用
IL312199A (en) * 2021-10-20 2024-06-01 Stealth Biotherapeutics Inc Methods and compositions containing peptide erasers for treating, preventing, delaying, ameliorating or delaying the onset of ocular conditions
CN115252555B (zh) * 2022-06-07 2023-11-21 西安电子科技大学 一种膜融合性脂质体、制备方法及其在蛋白质递送中的应用

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US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5858784A (en) 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
US5716644A (en) 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5674534A (en) 1992-06-11 1997-10-07 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
DE69936381T2 (de) * 1998-03-13 2007-10-31 The Johns Hopkins University School Of Medicine Verwendung von einem protein kinase hemmer wie z.b. genistein bei der behandlung von diabetischer retinopathie
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
US6217896B1 (en) 1999-04-01 2001-04-17 Uab Research Foundation Conjunctival inserts for topical delivery of medication or lubrication
US7550439B2 (en) 2004-01-23 2009-06-23 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
EP1931369B1 (en) * 2005-09-16 2016-08-17 Cornell Research Foundation, Inc. Aromatic-cationic peptide for use in a method for reducing CD36 expression
EP3797775A1 (en) * 2007-10-19 2021-03-31 Novartis AG Compositions and methods for treatment of diabetic retinopathy
EP3272353A1 (en) * 2008-02-07 2018-01-24 Cornell University Methods for preventing or treating insulin resistance
WO2009105690A2 (en) * 2008-02-21 2009-08-27 Targeted Genetics Corporation Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
WO2009108695A2 (en) * 2008-02-26 2009-09-03 Cornell University Methods for prevention and treatment of acute renal injury
EP3124036A1 (en) * 2009-08-24 2017-02-01 Stealth Peptides International, Inc. Methods and compositions for preventing or treating opthalmic conditions
CN102639141A (zh) * 2009-12-04 2012-08-15 欧几里得系统公司 用于预防和治疗黄斑变性、糖尿病性视网膜病变和糖尿病性黄斑水肿的组合物和方法
JP6319738B2 (ja) * 2010-07-09 2018-05-09 ステルス ペプチドズ インターナショナル インコーポレイテッド 虚血／再灌流障害に続くノーリフローの予防又は処置方法

Also Published As

Publication number Publication date
EP3281634A1 (en) 2018-02-14
WO2013126597A1 (en) 2013-08-29
JP2017214380A (ja) 2017-12-07
EP2817018A4 (en) 2015-09-23
US20180296630A1 (en) 2018-10-18
AU2019203713A1 (en) 2019-06-20
EP3479839A1 (en) 2019-05-08
CN104244964A (zh) 2014-12-24
AU2013222423A1 (en) 2014-09-11
US20160361377A1 (en) 2016-12-15
EP3078384A1 (en) 2016-10-12
JP2015509500A (ja) 2015-03-30
CA2865317A1 (en) 2013-08-29
CN105343869A (zh) 2016-02-24
AU2017254849A1 (en) 2017-11-16
JP2019034947A (ja) 2019-03-07
EP2817018A1 (en) 2014-12-31
US20150018288A1 (en) 2015-01-15

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