HK1203981A1 - Coagulation factor viii with reduced immunogenicity viii - Google Patents

Coagulation factor viii with reduced immunogenicity viii

Info

Publication number
HK1203981A1
HK1203981A1 HK15104600.7A HK15104600A HK1203981A1 HK 1203981 A1 HK1203981 A1 HK 1203981A1 HK 15104600 A HK15104600 A HK 15104600A HK 1203981 A1 HK1203981 A1 HK 1203981A1
Authority
HK
Hong Kong
Prior art keywords
viii
coagulation factor
reduced immunogenicity
factor viii
immunogenicity
Prior art date
Application number
HK15104600.7A
Other languages
English (en)
Chinese (zh)
Inventor
Jean-Marie Saint-Remy
Original Assignee
Imnate Sarl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imnate Sarl filed Critical Imnate Sarl
Publication of HK1203981A1 publication Critical patent/HK1203981A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/20—Ingredients acting on or related to the structure
    • A23V2200/218—Coagulant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0445—Proteins
    • A61M2202/0447—Glycoproteins
    • A61M2202/0452—Factor VIII

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15104600.7A 2012-05-22 2015-05-14 Coagulation factor viii with reduced immunogenicity viii HK1203981A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12168800.6A EP2666782A1 (de) 2012-05-22 2012-05-22 Gerinnungsfaktor VII mit reduzierter Immunogenität
PCT/EP2013/060397 WO2013174805A1 (en) 2012-05-22 2013-05-21 Coagulation factor viii with reduced immunogenicity

Publications (1)

Publication Number Publication Date
HK1203981A1 true HK1203981A1 (en) 2015-11-06

Family

ID=48485166

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15104600.7A HK1203981A1 (en) 2012-05-22 2015-05-14 Coagulation factor viii with reduced immunogenicity viii

Country Status (12)

Country Link
US (1) US10087233B2 (de)
EP (2) EP2666782A1 (de)
JP (1) JP6363996B2 (de)
AU (1) AU2013265400B2 (de)
BR (1) BR112014028575B1 (de)
CA (1) CA2872938C (de)
DK (1) DK2852609T3 (de)
ES (1) ES2751361T3 (de)
HK (1) HK1203981A1 (de)
IN (1) IN2014DN09216A (de)
RU (1) RU2631801C2 (de)
WO (1) WO2013174805A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3388447A1 (de) 2017-04-14 2018-10-17 Imnate Sarl Verfahren zur herstellung von peptiden, polypeptiden oder zellen zur modulation der immunität
EP3936867A1 (de) 2020-07-06 2022-01-12 Imnate Sarl Cd1 peptide-epitop zur verwendung bei der behandlung einer krankheit, die durch ein intrazelluläres pathogen verursacht wird

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7084251B1 (en) * 1987-02-12 2006-08-01 Genentech, Inc. Methods and Deoxyribonucleic acid for the preparation of tissue factor protein
US5859204A (en) * 1992-04-07 1999-01-12 Emory University Modified factor VIII
WO1995006737A1 (en) * 1993-09-03 1995-03-09 Kenneth Francis Prendergast Glycophorin binding protein (gbp130) fusion compositions
US6458563B1 (en) * 1996-06-26 2002-10-01 Emory University Modified factor VIII
BR0308860A (pt) * 2002-04-18 2005-01-04 Merck Patent Gmbh Fator viii modificado
WO2006053299A2 (en) * 2004-11-12 2006-05-18 Bayer Healthcare Llc Site-directed modification of fviii
EP1871801A2 (de) * 2005-04-01 2008-01-02 Novo Nordisk Health Care AG Analoga des blutgerinnungsfaktors fviii
US20090110861A1 (en) 2007-10-29 2009-04-30 3M Innovative Properties Company Pressure sensitive adhesive article
BRPI0818913A2 (pt) * 2007-11-01 2015-05-12 Univ Rochester Fator viii recombinante tendo elevada estabilidade
EP2249864B1 (de) 2008-02-14 2016-05-04 Life Sciences Research Partners VZW Strategien zur Prävention und/oder Behandlung von Immunantworten auf lösliche Allofaktoren
EP2149603A1 (de) * 2008-07-28 2010-02-03 DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH Faktor-IX-Varianten mit Gerinnungsaktivität in Abwesenheit ihres Cofaktors und ihre Verwendung zur Behandlung von Blutungsstörungen
US8691211B2 (en) * 2009-03-10 2014-04-08 Puget Sound Blood Center Suppression of immune response to factor VIII in hemophilia A patients
CA2780763A1 (en) * 2009-11-13 2011-05-19 Puget Sound Blood Center Factor viii b cell epitope variants having reduced immunogenicity
US9732118B2 (en) * 2010-11-25 2017-08-15 Imnate Sarl Modulation of antigen immunogenicity by deleting epitopes recognized by NKT cells

Also Published As

Publication number Publication date
BR112014028575B1 (pt) 2022-08-30
IN2014DN09216A (de) 2015-07-10
CA2872938A1 (en) 2013-11-28
ES2751361T3 (es) 2020-03-31
JP2015518844A (ja) 2015-07-06
WO2013174805A1 (en) 2013-11-28
EP2666782A1 (de) 2013-11-27
BR112014028575A2 (pt) 2017-08-01
DK2852609T3 (da) 2019-11-25
RU2631801C2 (ru) 2017-09-26
US10087233B2 (en) 2018-10-02
US20150087593A1 (en) 2015-03-26
EP2852609B1 (de) 2019-10-09
AU2013265400B2 (en) 2017-07-27
EP2852609A1 (de) 2015-04-01
AU2013265400A1 (en) 2014-11-13
CA2872938C (en) 2020-06-16
JP6363996B2 (ja) 2018-07-25
RU2014151719A (ru) 2016-07-10

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