HK1203525A1 - Solid phase peptide synthesis of insulin using side chain anchored lysine - Google Patents
Solid phase peptide synthesis of insulin using side chain anchored lysineInfo
- Publication number
- HK1203525A1 HK1203525A1 HK15104038.9A HK15104038A HK1203525A1 HK 1203525 A1 HK1203525 A1 HK 1203525A1 HK 15104038 A HK15104038 A HK 15104038A HK 1203525 A1 HK1203525 A1 HK 1203525A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- insulin
- lysine
- side chain
- solid phase
- peptide synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261636193P | 2012-04-20 | 2012-04-20 | |
PCT/IB2013/053111 WO2013156977A1 (en) | 2012-04-20 | 2013-04-19 | Solid phase peptide synthesis of insulin using side chain anchored lysine |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1203525A1 true HK1203525A1 (en) | 2015-10-30 |
Family
ID=48539334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15104038.9A HK1203525A1 (en) | 2012-04-20 | 2015-04-27 | Solid phase peptide synthesis of insulin using side chain anchored lysine |
Country Status (10)
Country | Link |
---|---|
US (2) | US20160031962A1 (de) |
EP (1) | EP2838915B1 (de) |
CN (1) | CN104428314B (de) |
BR (1) | BR112014026077B1 (de) |
CA (1) | CA2870891C (de) |
HK (1) | HK1203525A1 (de) |
IL (1) | IL235183B (de) |
IN (1) | IN2014DN09089A (de) |
NZ (1) | NZ631001A (de) |
WO (1) | WO2013156977A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106432472B (zh) * | 2016-10-24 | 2020-01-03 | 合肥国肽生物科技有限公司 | 一种胰岛素的固相合成方法 |
CN110072878B (zh) | 2016-12-16 | 2021-07-23 | 中国医学科学院医药生物技术研究所 | 多粘菌素衍生物及其制备方法和应用 |
US20210214412A1 (en) * | 2018-04-16 | 2021-07-15 | University Of Utah Research Foundation | Glucose-responsive insulin |
CN111518009B (zh) * | 2019-02-01 | 2023-06-23 | 鲁南制药集团股份有限公司 | 一种脂肪酸衍生物及其合成方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6562942B1 (en) * | 1999-02-23 | 2003-05-13 | Neurocrine Biosciences, Inc. | Methods for treatment of diabetes using peptide analogues of insulin |
AU2003302239A1 (en) * | 2002-12-06 | 2004-06-30 | Adaptive Therapeutics, Inc. | Novel cyclic peptides comprising cis-3 aminocycloalkanecarboxylic acids |
EP1660531A2 (de) * | 2003-08-05 | 2006-05-31 | Novo Nordisk A/S | Neue insulinderivate |
JP4933455B2 (ja) * | 2005-02-02 | 2012-05-16 | ノヴォ ノルディスク アー/エス | 新規のインスリン誘導体 |
CA2665559A1 (en) * | 2006-10-05 | 2008-04-10 | Lonza Ag | Method for peptide synthesis |
WO2008109079A2 (en) * | 2007-03-01 | 2008-09-12 | Novetide, Ltd. | High purity peptides |
CN102414220A (zh) * | 2009-05-01 | 2012-04-11 | 霍夫曼-拉罗奇有限公司 | 使用固相和液相组合技术的促胰岛素肽合成 |
GR1007010B (el) * | 2009-10-08 | 2010-10-07 | Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), | Ινσουλινοειδη πεπτιδια |
-
2012
- 2012-04-20 US US14/395,313 patent/US20160031962A1/en not_active Abandoned
-
2013
- 2013-04-19 EP EP13726299.4A patent/EP2838915B1/de active Active
- 2013-04-19 CN CN201380031205.XA patent/CN104428314B/zh active Active
- 2013-04-19 WO PCT/IB2013/053111 patent/WO2013156977A1/en active Application Filing
- 2013-04-19 BR BR112014026077-0A patent/BR112014026077B1/pt active IP Right Grant
- 2013-04-19 CA CA2870891A patent/CA2870891C/en active Active
- 2013-04-19 NZ NZ631001A patent/NZ631001A/en unknown
-
2014
- 2014-10-19 IL IL235183A patent/IL235183B/en active IP Right Grant
- 2014-10-30 IN IN9089DEN2014 patent/IN2014DN09089A/en unknown
-
2015
- 2015-04-27 HK HK15104038.9A patent/HK1203525A1/xx unknown
-
2021
- 2021-06-16 US US17/349,578 patent/US20210388051A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2013156977A1 (en) | 2013-10-24 |
IL235183B (en) | 2018-01-31 |
CA2870891A1 (en) | 2013-10-24 |
NZ631001A (en) | 2017-05-26 |
US20210388051A1 (en) | 2021-12-16 |
IN2014DN09089A (de) | 2015-05-22 |
CA2870891C (en) | 2022-04-05 |
BR112014026077B1 (pt) | 2022-03-08 |
EP2838915A1 (de) | 2015-02-25 |
EP2838915B1 (de) | 2018-05-30 |
CN104428314A (zh) | 2015-03-18 |
BR112014026077A2 (pt) | 2017-06-27 |
US20160031962A1 (en) | 2016-02-04 |
AU2013250755A1 (en) | 2014-11-06 |
CN104428314B (zh) | 2021-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AM | Amended specification (according sect 146 of patent law) |
Free format text: ADDITION OF INVENTOR UNDER: KONSTANTINOS BARLOS - DIMITRIOS GATOS - MICHAIL ZIOVAS - EFSTATHIOS LIOPYRIS - REQUEST FOR CORRECTION ALLOWED ON 04.07.2018 Effective date: 20180704 |