HK1203069A1 - Process for the preparation of substituted 3-(1-amino-2-methyl- pentane-3-yl)phenyl compounds 3-(1--2--3-) - Google Patents
Process for the preparation of substituted 3-(1-amino-2-methyl- pentane-3-yl)phenyl compounds 3-(1--2--3-)Info
- Publication number
- HK1203069A1 HK1203069A1 HK15103620.5A HK15103620A HK1203069A1 HK 1203069 A1 HK1203069 A1 HK 1203069A1 HK 15103620 A HK15103620 A HK 15103620A HK 1203069 A1 HK1203069 A1 HK 1203069A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pentane
- amino
- substituted
- methyl
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10006201 | 2010-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1203069A1 true HK1203069A1 (en) | 2015-10-16 |
Family
ID=43086453
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15103620.5A HK1203069A1 (en) | 2010-06-15 | 2013-10-03 | Process for the preparation of substituted 3-(1-amino-2-methyl- pentane-3-yl)phenyl compounds 3-(1--2--3-) |
| HK13111244.6A HK1184434A1 (en) | 2010-06-15 | 2013-10-03 | Process for the preparation of substituted 3-(1-amino-2-methylpentane-3- yl)phenyl compounds 3-(1--2--3-) |
| HK15112413.7A HK1211568A1 (en) | 2010-06-15 | 2015-12-17 | Process for the preparation of substituted 3-(1-amino-2- methylpentane-3-yl)phenyl compounds 3-(1--2--3-) |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13111244.6A HK1184434A1 (en) | 2010-06-15 | 2013-10-03 | Process for the preparation of substituted 3-(1-amino-2-methylpentane-3- yl)phenyl compounds 3-(1--2--3-) |
| HK15112413.7A HK1211568A1 (en) | 2010-06-15 | 2015-12-17 | Process for the preparation of substituted 3-(1-amino-2- methylpentane-3-yl)phenyl compounds 3-(1--2--3-) |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8669399B2 (fr) |
| EP (3) | EP2666765B1 (fr) |
| CN (3) | CN103168025B (fr) |
| HK (3) | HK1203069A1 (fr) |
| IL (4) | IL221925A (fr) |
| WO (1) | WO2011157390A2 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102617501A (zh) | 2011-01-31 | 2012-08-01 | 中国科学院上海药物研究所 | 取代正戊酰胺类化合物、其制备方法及用途 |
| US8853393B2 (en) * | 2011-07-29 | 2014-10-07 | Anhui New Star Pharmaceutical Development Co., Ltd. | Intermediate for preparing tapentadol or analogues thereof |
| EP2674414A1 (fr) | 2012-06-15 | 2013-12-18 | Siegfried AG | Appareils dýimpression |
| CN102936205B (zh) * | 2012-11-12 | 2014-06-18 | 合肥市新星医药化工有限公司 | 一种他喷他多的合成方法 |
| US9090539B2 (en) * | 2013-05-24 | 2015-07-28 | Ampac Fine Chemicals Llc | Compounds and methods for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds |
| CZ307492B6 (cs) | 2014-02-04 | 2018-10-17 | Zentiva, K.S. | Pevná forma maleátu tapentadolu a způsob její přípravy |
| ES2940904T3 (es) | 2014-07-10 | 2023-05-12 | SpecGx LLC | Procedimiento para preparar fenilalcanos sustituidos |
| EP3180309A1 (fr) * | 2014-08-11 | 2017-06-21 | Sandoz AG | Procédé de préparation du 3-[(1r,2r)-3-(diméthylamino)-1-éthyl-2-méthylpropyl]-phénol |
| MX370658B (es) * | 2015-07-10 | 2019-12-19 | SpecGx LLC | Proceso en dos etapas para preparar fenilalquilaminas sustituidas en la posición 3. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) * | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| SE0004827D0 (sv) * | 2000-12-22 | 2000-12-22 | Astrazeneca Ab | Therapeutic compounds |
| DE10326097A1 (de) * | 2003-06-06 | 2005-01-05 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-butyl)-aminverbindungen |
| CN1849121A (zh) | 2003-06-20 | 2006-10-18 | 安姆根有限公司 | 作为缓激肽拮抗剂的哌嗪衍生物 |
| DE10328316A1 (de) * | 2003-06-23 | 2005-01-20 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe |
| JP5117382B2 (ja) * | 2006-05-31 | 2013-01-16 | 第一三共株式会社 | ７員環化合物の製造方法 |
| TWI401237B (zh) * | 2006-07-24 | 2013-07-11 | ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備 | |
| TWI448447B (zh) | 2006-07-24 | 2014-08-11 | Gruenenthal Chemie | 製備（１ｒ，２ｒ）-３-（３-二甲胺基-１-乙基-２-甲基-丙基）-酚之方法 |
| EP2519100B1 (fr) * | 2009-12-29 | 2017-03-15 | Mapi Pharma Limited | Composés intermédiaires et procédés pour la préparation de tapentadol et de composés apparentés |
-
2011
- 2011-06-14 CN CN201180029409.0A patent/CN103168025B/zh active Active
- 2011-06-14 WO PCT/EP2011/002904 patent/WO2011157390A2/fr active Application Filing
- 2011-06-14 EP EP13004106.4A patent/EP2666765B1/fr active Active
- 2011-06-14 CN CN201510024698.5A patent/CN104725245A/zh active Pending
- 2011-06-14 US US13/160,050 patent/US8669399B2/en active Active
- 2011-06-14 EP EP14002207.0A patent/EP2792668B1/fr active Active
- 2011-06-14 CN CN201510024860.3A patent/CN104725246B/zh active Active
- 2011-06-14 EP EP11733993.7A patent/EP2582659B1/fr active Active
-
2012
- 2012-09-13 IL IL221925A patent/IL221925A/en active IP Right Grant
-
2013
- 2013-08-21 US US13/972,253 patent/US9388119B2/en active Active
- 2013-10-03 HK HK15103620.5A patent/HK1203069A1/xx unknown
- 2013-10-03 HK HK13111244.6A patent/HK1184434A1/xx unknown
-
2014
- 2014-04-29 IL IL232319A patent/IL232319B/en active IP Right Grant
- 2014-04-29 IL IL232318A patent/IL232318A/en active IP Right Grant
-
2015
- 2015-12-17 HK HK15112413.7A patent/HK1211568A1/xx unknown
-
2016
- 2016-05-17 US US15/157,216 patent/US9850198B2/en active Active
-
2018
- 2018-03-08 IL IL257977A patent/IL257977A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN104725246A (zh) | 2015-06-24 |
| WO2011157390A3 (fr) | 2012-03-15 |
| US9388119B2 (en) | 2016-07-12 |
| CN103168025A (zh) | 2013-06-19 |
| IL221925A (en) | 2015-06-30 |
| EP2582659B1 (fr) | 2015-03-11 |
| HK1211568A1 (en) | 2016-05-27 |
| WO2011157390A2 (fr) | 2011-12-22 |
| EP2666765A3 (fr) | 2013-12-11 |
| US20130338399A1 (en) | 2013-12-19 |
| IL232319B (en) | 2018-05-31 |
| US20110306793A1 (en) | 2011-12-15 |
| CN104725245A (zh) | 2015-06-24 |
| US9850198B2 (en) | 2017-12-26 |
| US20160257640A1 (en) | 2016-09-08 |
| US8669399B2 (en) | 2014-03-11 |
| EP2666765B1 (fr) | 2017-01-04 |
| IL232319A0 (en) | 2014-06-30 |
| CN103168025B (zh) | 2015-02-25 |
| IL257977A (en) | 2018-05-31 |
| CN104725246B (zh) | 2017-05-03 |
| IL232318A0 (en) | 2014-06-30 |
| EP2666765A2 (fr) | 2013-11-27 |
| EP2792668B1 (fr) | 2017-05-31 |
| IL232318A (en) | 2017-01-31 |
| HK1184434A1 (en) | 2014-01-24 |
| EP2582659A2 (fr) | 2013-04-24 |
| EP2792668A1 (fr) | 2014-10-22 |
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