HK1202429A1 - 用於防止和治療急性腎損傷的方法 - Google Patents

用於防止和治療急性腎損傷的方法

Info

Publication number
HK1202429A1
HK1202429A1 HK15102987.4A HK15102987A HK1202429A1 HK 1202429 A1 HK1202429 A1 HK 1202429A1 HK 15102987 A HK15102987 A HK 15102987A HK 1202429 A1 HK1202429 A1 HK 1202429A1
Authority
HK
Hong Kong
Prior art keywords
prevention
treatment
methods
acute renal
renal injury
Prior art date
Application number
HK15102987.4A
Other languages
English (en)
Inventor
Hazel H Szeto
Diane Felsen
Original Assignee
Univ Cornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cornell filed Critical Univ Cornell
Publication of HK1202429A1 publication Critical patent/HK1202429A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK15102987.4A 2008-02-26 2015-03-24 用於防止和治療急性腎損傷的方法 HK1202429A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3158508P 2008-02-26 2008-02-26

Publications (1)

Publication Number Publication Date
HK1202429A1 true HK1202429A1 (zh) 2015-10-02

Family

ID=41013650

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15102987.4A HK1202429A1 (zh) 2008-02-26 2015-03-24 用於防止和治療急性腎損傷的方法
HK18106280.6A HK1246673A1 (zh) 2008-02-26 2018-05-15 用於預防和治療急性腎損傷的肽

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18106280.6A HK1246673A1 (zh) 2008-02-26 2018-05-15 用於預防和治療急性腎損傷的肽

Country Status (7)

Country Link
US (9) US8143219B2 (zh)
EP (3) EP3243521B1 (zh)
JP (5) JP5677096B2 (zh)
CN (4) CN104056248A (zh)
DK (1) DK2262520T3 (zh)
HK (2) HK1202429A1 (zh)
WO (1) WO2009108695A2 (zh)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2604621B1 (en) 2003-05-01 2015-10-21 Cornell Research Foundation, Inc. Method and carrier complexes for delivering molecules to cells
CN102552874B (zh) 2005-09-16 2015-04-22 科内尔研究基金会 用于减少cd36表达的方法
JP5677096B2 (ja) 2008-02-26 2015-02-25 コーネル ユニヴァーシティー 急性腎障害を予防および治療するための方法
US20100331265A1 (en) 2009-03-20 2010-12-30 Tompkins Ronald G Methods for the prevention and treatment of burn injuries and secondary complications
US20110039766A1 (en) * 2009-08-12 2011-02-17 Szeto Hazel H Methods for preventing or treating metabolic syndrome
EP3318264A1 (en) * 2009-08-24 2018-05-09 Stealth Peptides International, Inc. Methods ans compositions for preventing or treating opthalmic conditions
EP2764871A1 (en) * 2009-10-05 2014-08-13 Cornell University Methods for the prevention or treatment of heart failure
CN103751763A (zh) * 2009-12-31 2014-04-30 康肽德生物医药技术有限公司 用于预防或治疗血管阻塞损伤的方法
US20130190244A1 (en) * 2009-12-31 2013-07-25 Stealth Peptides International, Inc. Methods for performing a coronary artery bypass graft procedure
EP2528934A4 (en) * 2010-01-25 2013-08-21 Univ Cornell AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
US8585597B2 (en) * 2010-03-12 2013-11-19 Sonogenix, Inc. Renal injury inhibiting devices, systems, and methods employing low-frequency ultrasound or other cyclical pressure energies
US8697657B2 (en) 2010-03-15 2014-04-15 Stealth Peptides International, Inc. Combination therapies using cyclosporine and aromatic cationic peptides
EP2566880A4 (en) * 2010-05-03 2014-10-08 Stealth Peptides Int Inc AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
WO2012092238A1 (en) * 2010-12-31 2012-07-05 Zeus Scientific, Inc. Improved methods for determining cell viability using molecular nucleic acid-based techniques
CN109705192A (zh) * 2011-03-24 2019-05-03 康奈尔大学 芳香族阳离子肽及其用途
WO2012158518A1 (en) * 2011-05-13 2012-11-22 The Penn State Research Foundation Treatment of renal injury
JP2014522879A (ja) * 2011-08-10 2014-09-08 ディグナ ビオテク、エセ エレ 腎疾患の治療のためのカルジオトロフィン−1の使用
CA3123992A1 (en) 2011-09-29 2013-04-04 Mayo Foundation For Medical Education And Research Aromatic-cationic peptides and methods for using same
EP2768516A4 (en) * 2011-10-17 2015-08-19 Univ Cornell AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
US9353171B2 (en) 2011-11-17 2016-05-31 The Administrators Of The Tulane Educational Fund Use of pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP analogs for treating contrast-induced nephropathy
CN104105499A (zh) * 2011-12-09 2014-10-15 康肽德生物医药技术有限公司 芳香族阳离子肽及其用途
EP2817018A4 (en) * 2012-02-22 2015-09-23 Stealth Peptides Int Inc METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
EP2817021B1 (en) * 2012-02-23 2019-01-02 Cornell University Aromatic-cationic peptides and uses of same
CN107320712A (zh) * 2012-03-30 2017-11-07 康德生物医疗技术公司 用于预防和治疗神经病的方法和组合物
CN110193077A (zh) * 2012-10-22 2019-09-03 康德生物医疗技术公司 降低与心脏衰竭相关的风险和与其相关的因素的方法
HUE046924T2 (hu) * 2013-03-01 2020-03-30 Stealth Biotherapeutics Corp Módszerek és készítmények Barth szindróma megelõzésében vagy kezelésében történõ alkalmazásra
EP3673913A1 (en) * 2013-03-01 2020-07-01 Stealth Biotherapeutics Corp Methods for the treatment of mitochondrial disease
CA2916977A1 (en) 2013-06-26 2014-12-31 Stealth Biotherapeutics Corp Methods and compositions for detecting and diagnosing diseases and conditions
WO2015089316A1 (en) * 2013-12-12 2015-06-18 Cornell University Methods for preventing and treating oral cancers
JP6728536B2 (ja) * 2014-03-31 2020-07-22 ゾール メディカル コーポレイションZOLL Medical Corporation 蘇生後症候群を治療するための炎症性バイオマーカーの血液濾過
ES2869430T3 (es) 2014-06-25 2021-10-25 Flamma Spa Procedimiento para preparar D-arginil-2,6-dimetil-L-tirosil-L-lisil-L-fenilalaninamida
HUE055687T2 (hu) 2014-06-30 2021-12-28 Flamma Spa Eljárás D-arginil-2,6-dimetil-L-tirozil-L-lizil-L-fenilalaninamid elõállítására
WO2016029027A2 (en) * 2014-08-21 2016-02-25 Stealth Biotherapeutics Corp Methods and compositions for the prevention and treatment of disease
EP3442990A4 (en) 2016-04-11 2019-12-18 Carnot, LLC CHIRAL PEPTIDES
CN107644976B (zh) * 2016-07-22 2020-09-29 清华大学 锂离子电池电极
US11123345B2 (en) 2016-11-21 2021-09-21 Saghmos Therapeutics, Inc. Prevention and/or treatment of contrast-induced acute kidney injury
SG11202002882VA (en) 2017-10-03 2020-04-29 The United States Of America As Represented By The Secretary Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents
WO2020018381A1 (en) 2018-07-18 2020-01-23 The Regents Of The University Of California Kidney injury treatment
CN109946139A (zh) * 2019-02-28 2019-06-28 东南大学 一种石蜡切片免疫组化套染pas试剂盒及其染色方法和应用
CN111686239B (zh) * 2019-03-11 2021-12-24 中国科学院微生物研究所 抗真菌化合物的应用
WO2020214518A1 (en) * 2019-04-18 2020-10-22 Arcuate Therapeutics, Inc. Methods of treating renal conditions using peptides that improve mitochondrial function
CN110250110A (zh) * 2019-07-11 2019-09-20 南京医科大学附属逸夫医院 一种顺铂所致急性肾损伤的小鼠模型的构建方法
EP3771467A1 (en) 2019-07-30 2021-02-03 Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau Ss-31 for the prevention and/or treatment of aneurysm
CN113209294B (zh) * 2020-02-05 2023-06-13 复旦大学 Dor激动剂在制备对抗肾脏纤维化药物中的应用
CN111419860A (zh) * 2020-03-19 2020-07-17 长春市儿童医院 一种肾小球分叶状肾病造模方法
KR102308991B1 (ko) 2020-04-08 2021-10-06 압타바이오 주식회사 조영제 유발 급성 신부전 치료제
WO2021206316A1 (ko) 2020-04-08 2021-10-14 압타바이오 주식회사 조영제 유발 급성 신부전 치료제
CN111933006B (zh) * 2020-07-30 2022-06-03 四川大学华西医院 一种模拟巨噬细胞改善小鼠急性肾损伤实验的方法及系统
IL301158A (en) 2020-09-09 2023-05-01 Social Profit Network Methods and preparations for delivering biotin to mitochondria
KR20230112608A (ko) * 2020-09-11 2023-07-27 레니버스 테라퓨틱스, 인크. 신장 보호와 함께 암을 치료하는 방법

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
SG64368A1 (en) 1988-06-30 1999-04-27 Astra Ab Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same
US5602100A (en) 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
US5670617A (en) 1989-12-21 1997-09-23 Biogen Inc Nucleic acid conjugates of tat-derived transport polypeptides
US5858784A (en) 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
US5716644A (en) 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5674534A (en) 1992-06-11 1997-10-07 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
WO1994028012A1 (en) * 1993-05-28 1994-12-08 Warner-Lambert Company Hydroxamate inhibitors of endothelin converting enzyme
IS4261A (is) 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
EP0747092B1 (en) 1995-06-09 2003-12-03 Hisamitsu Pharmaceutical Co., Inc. Matrix for iontophoresis
US5849761A (en) 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US5885958A (en) 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
US6221355B1 (en) 1997-12-10 2001-04-24 Washington University Anti-pathogen system and methods of use thereof
CA2329709A1 (en) 1998-04-24 1999-11-04 Mitokor Compounds and methods for treating mitochondria-associated diseases
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
SE9900961D0 (sv) 1999-03-16 1999-03-16 Astra Ab Novel compounds
CA2386540A1 (en) 1999-10-04 2001-04-12 University Of Medicine And Dentistry Of New Jersey Novel carbamates and ureas
US6759520B1 (en) 1999-10-28 2004-07-06 The New England Medical Center Hospitals, Inc. Chimeric analgesic peptides
US20050192215A1 (en) 2000-01-21 2005-09-01 Malabika Ghosh Methods and materials relating to novel polypeptides and polynucleotides
CA2400628A1 (en) 2000-03-09 2001-09-13 Genzyme Corporation Use of tgf-beta antagonists to treat or to prevent loss of renal function
AU2001277908A1 (en) 2000-07-18 2002-01-30 Cornell Research Foundation Inc. Medicinal uses of mu-opioid receptor agonists
US6900178B2 (en) 2000-09-12 2005-05-31 University Of Kentucky Research Foundation Protection against ischemia and reperfusion injury
CA2447008A1 (en) 2001-04-05 2002-10-24 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US20070015146A1 (en) 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
CN104225574B (zh) 2003-02-04 2017-01-11 科内尔研究基金会 用于防止线粒体通透性改变的方法
EP2604621B1 (en) 2003-05-01 2015-10-21 Cornell Research Foundation, Inc. Method and carrier complexes for delivering molecules to cells
WO2005032481A2 (en) 2003-09-30 2005-04-14 Scios Inc. Quinazoline derivatives as medicaments
JP4931604B2 (ja) * 2004-01-23 2012-05-16 コーネル リサーチ ファウンデイション インコーポレイテッド 酸化的損傷を低減する方法
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
CN102552874B (zh) * 2005-09-16 2015-04-22 科内尔研究基金会 用于减少cd36表达的方法
US20080027082A1 (en) * 2006-06-19 2008-01-31 Berthold Hocher Use of adenosine a1 antagonists in radiocontrast media induced nephropathy
JP5677096B2 (ja) 2008-02-26 2015-02-25 コーネル ユニヴァーシティー 急性腎障害を予防および治療するための方法

Also Published As

Publication number Publication date
US20190388492A1 (en) 2019-12-26
US20170112893A1 (en) 2017-04-27
EP2262520A4 (en) 2012-02-29
WO2009108695A2 (en) 2009-09-03
CN106975070A (zh) 2017-07-25
JP2011513241A (ja) 2011-04-28
DK2262520T3 (en) 2017-08-07
CN107802821A (zh) 2018-03-16
WO2009108695A3 (en) 2009-12-30
US11628198B2 (en) 2023-04-18
JP5677096B2 (ja) 2015-02-25
US20230398172A1 (en) 2023-12-14
EP3741381A1 (en) 2020-11-25
US20210023161A1 (en) 2021-01-28
US8143219B2 (en) 2012-03-27
JP2016175924A (ja) 2016-10-06
US20140107033A1 (en) 2014-04-17
JP2015063561A (ja) 2015-04-09
CN104056248A (zh) 2014-09-24
EP2262520B1 (en) 2017-05-03
JP2017226697A (ja) 2017-12-28
US8592373B2 (en) 2013-11-26
CN101951936A (zh) 2011-01-19
EP3243521B1 (en) 2020-05-27
EP3243521A1 (en) 2017-11-15
HK1246673A1 (zh) 2018-09-14
US20150353602A1 (en) 2015-12-10
US8940696B2 (en) 2015-01-27
EP2262520A2 (en) 2010-12-22
JP2019059785A (ja) 2019-04-18
EP3741381B1 (en) 2024-04-24
US20180177840A1 (en) 2018-06-28
US20090221514A1 (en) 2009-09-03
US20130017150A1 (en) 2013-01-17

Similar Documents

Publication Publication Date Title
HK1202429A1 (zh) 用於防止和治療急性腎損傷的方法
IL209895A (en) Compounds for the prevention and / or treatment of β-amyloidoses
ZA201303605B (en) Compounds and methods for treating pain
IL208354A0 (en) Methods of treatment
IL202015A0 (en) Methods and compositions for treating skin conditions
HK1162366A1 (zh) 用於治療和/或預防疾病的裝置和方法
EP2170311A4 (en) COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES
EP2318406A4 (en) THIOSEMICARBAZONHERMAL COMPOUNDS AND CANCER TREATMENT PROCEDURES
EP2361089A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF ALTERED FUNCTION OF -SYNUCLEINE
IL209216A0 (en) Methods for preventing and treating neurodegenerative diseases
EP2334315A4 (en) MEANS AND METHOD OF TREATMENT TREATMENT
EP2497482A4 (en) COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF INFLUENZA AVIRUSED INDUCED DISEASES
IL210097A0 (en) Compositions and methods for treating unfluenza
IL204728A0 (en) Methods and compounds for treating retinol-related diseases
EP2341936A4 (en) METHOD FOR TREATING OR PREVENTING IL-1ß-CONTAINED ILLNESSES
EP2350641A4 (en) Methods of Treatment
PL3216457T3 (pl) Związki i sposoby zapobiegania lub leczenia restenozy
IL207127A0 (en) Aldh-2 inhibitors in the treatment of addiction
IL210840A0 (en) Methods and compositions for treating and preventing autoimmune diseases
HK1153465A1 (zh) 大環化合物和治療方法
EP2367544A4 (en) METHOD FOR TREATING AGGRESSION
EP2470020A4 (en) BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH
EP2164494A4 (en) Methods of Treatment
EP2512504A4 (en) COMPOSITION AND THERAPEUTIC METHOD
IL208231A0 (en) Agent for preventing and/or treating vascular diseases