HK1202125A1 - Process for the synthesis of therapeutic peptides - Google Patents
Process for the synthesis of therapeutic peptidesInfo
- Publication number
- HK1202125A1 HK1202125A1 HK15102654.6A HK15102654A HK1202125A1 HK 1202125 A1 HK1202125 A1 HK 1202125A1 HK 15102654 A HK15102654 A HK 15102654A HK 1202125 A1 HK1202125 A1 HK 1202125A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- synthesis
- therapeutic peptides
- peptides
- therapeutic
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161580089P | 2011-12-23 | 2011-12-23 | |
| PCT/IB2012/003056 WO2013093639A1 (en) | 2011-12-23 | 2012-12-21 | Process for the synthesis of therapeutic peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1202125A1 true HK1202125A1 (en) | 2015-09-18 |
Family
ID=48095921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15102654.6A HK1202125A1 (en) | 2011-12-23 | 2015-03-16 | Process for the synthesis of therapeutic peptides |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US9475837B2 (xx) |
| EP (1) | EP2794634B1 (xx) |
| JP (1) | JP6192657B2 (xx) |
| KR (1) | KR101996700B1 (xx) |
| CN (1) | CN104080795A (xx) |
| AU (1) | AU2012356321B2 (xx) |
| BR (1) | BR112014015275A8 (xx) |
| CA (1) | CA2856257A1 (xx) |
| ES (1) | ES2663869T3 (xx) |
| HK (1) | HK1202125A1 (xx) |
| MX (1) | MX350536B (xx) |
| RU (1) | RU2625793C2 (xx) |
| UA (1) | UA115542C2 (xx) |
| WO (1) | WO2013093639A1 (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251933A (zh) | 2005-09-29 | 2013-08-21 | 益普生制药股份有限公司 | 用于刺激胃肠运动性的组合物和方法 |
| WO2014147124A1 (en) | 2013-03-21 | 2014-09-25 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
| US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
| CN106459149A (zh) * | 2014-03-04 | 2017-02-22 | 莫图斯治疗公司 | H‑inp‑(d)bal‑(d)trp‑phe‑apc‑nh2及其可药用盐的液相合成的方法 |
| CN110294789A (zh) * | 2018-03-21 | 2019-10-01 | 海南大学 | 含多巴寡肽的合成方法及其在抗帕金森病前药方面的应用 |
| CN110317188B (zh) * | 2018-03-29 | 2023-01-17 | 深圳翰宇药业股份有限公司 | 化合物及其制备方法和应用 |
| WO2020017919A1 (ko) * | 2018-07-19 | 2020-01-23 | 한미정밀화학주식회사 | 생리활성 폴리펩타이드에 사용되는 신규한 중간체 및 이의 제조방법 |
| EP3914605B1 (en) | 2019-01-24 | 2022-12-07 | DSM IP Assets B.V. | Peptide precipitation method |
| EP3939990A4 (en) * | 2019-02-15 | 2023-05-24 | Hanmi Fine Chemical Co., Ltd. | NEW INTERMEDIATE USED FOR A BIOLOGICALLY ACTIVE POLYPEPTIDE AND METHOD FOR PREPARING IT |
| GB2590341A (en) * | 2019-10-04 | 2021-06-23 | Tiburio Therapeutics Inc | Storage stable somatostatin-dopamine chimeric compounds and salt forms thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5117009A (en) * | 1990-08-31 | 1992-05-26 | University Of Minnesota | Xanthenylamide handle for use in peptide synthesis |
| US7244721B2 (en) * | 2000-07-21 | 2007-07-17 | Schering Corporation | Peptides as NS3-serine protease inhibitors of hepatitis C virus |
| WO2002100888A1 (en) | 2001-06-08 | 2002-12-19 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Somatostatin-dopamine chimeric analogs |
| JP4276462B2 (ja) * | 2002-04-11 | 2009-06-10 | アスビオファーマ株式会社 | 修飾ペプチドの製造方法 |
| TWI331922B (en) * | 2002-08-09 | 2010-10-21 | Ipsen Pharma Sas | Growth hormone releasing peptides |
| JP4579235B2 (ja) | 2003-04-11 | 2010-11-10 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | ソマトスタチン−ドーパミンキメラ類似体 |
| JP4879265B2 (ja) * | 2005-07-22 | 2012-02-22 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | 成長ホルモン分泌促進薬 |
| WO2007106385A2 (en) * | 2006-03-10 | 2007-09-20 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment |
| WO2007139589A1 (en) * | 2006-05-26 | 2007-12-06 | Bristol-Myers Squibb Company | Sustained release glp-1 receptor modulators |
| CN101538316B (zh) * | 2009-01-13 | 2012-09-05 | 深圳翰宇药业股份有限公司 | 一种固相法制备Eptifibatide的方法 |
| WO2010141276A1 (en) * | 2009-06-03 | 2010-12-09 | Mallinckrodt Inc. | Solid phase peptide synthesis process for the production of goserelin |
-
2012
- 2012-12-21 RU RU2014130277A patent/RU2625793C2/ru active
- 2012-12-21 BR BR112014015275A patent/BR112014015275A8/pt active Search and Examination
- 2012-12-21 EP EP12840868.9A patent/EP2794634B1/en not_active Not-in-force
- 2012-12-21 CN CN201280062490.7A patent/CN104080795A/zh active Pending
- 2012-12-21 ES ES12840868.9T patent/ES2663869T3/es active Active
- 2012-12-21 WO PCT/IB2012/003056 patent/WO2013093639A1/en active Application Filing
- 2012-12-21 US US14/368,154 patent/US9475837B2/en active Active
- 2012-12-21 AU AU2012356321A patent/AU2012356321B2/en not_active Ceased
- 2012-12-21 MX MX2014007263A patent/MX350536B/es active IP Right Grant
- 2012-12-21 JP JP2014548246A patent/JP6192657B2/ja not_active Expired - Fee Related
- 2012-12-21 KR KR1020147020136A patent/KR101996700B1/ko active IP Right Grant
- 2012-12-21 CA CA2856257A patent/CA2856257A1/en not_active Abandoned
- 2012-12-21 UA UAA201408394A patent/UA115542C2/uk unknown
-
2015
- 2015-03-16 HK HK15102654.6A patent/HK1202125A1/xx unknown
-
2016
- 2016-10-24 US US15/332,208 patent/US20170137489A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2663869T3 (es) | 2018-04-17 |
| BR112014015275A2 (pt) | 2017-06-13 |
| CN104080795A (zh) | 2014-10-01 |
| AU2012356321B2 (en) | 2015-09-17 |
| EP2794634B1 (en) | 2018-01-24 |
| MX2014007263A (es) | 2014-08-01 |
| US20170137489A1 (en) | 2017-05-18 |
| BR112014015275A8 (pt) | 2017-06-13 |
| WO2013093639A1 (en) | 2013-06-27 |
| KR101996700B1 (ko) | 2019-07-04 |
| MX350536B (es) | 2017-09-08 |
| CA2856257A1 (en) | 2013-06-27 |
| RU2014130277A (ru) | 2016-02-20 |
| AU2012356321A1 (en) | 2014-07-17 |
| RU2625793C2 (ru) | 2017-07-19 |
| US9475837B2 (en) | 2016-10-25 |
| EP2794634A1 (en) | 2014-10-29 |
| US20150045534A1 (en) | 2015-02-12 |
| UA115542C2 (uk) | 2017-11-27 |
| JP2015504045A (ja) | 2015-02-05 |
| KR20140113696A (ko) | 2014-09-24 |
| JP6192657B2 (ja) | 2017-09-06 |
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