HK1201919A1 - Vibrio cholerae lipoprotein 15 (lp15) variants as anti-interference additive in tpn17-based immunoassays for detection of anti-treponema antibodies vclp15 tpn17 - Google Patents

Vibrio cholerae lipoprotein 15 (lp15) variants as anti-interference additive in tpn17-based immunoassays for detection of anti-treponema antibodies vclp15 tpn17

Info

Publication number
HK1201919A1
HK1201919A1 HK15102351.2A HK15102351A HK1201919A1 HK 1201919 A1 HK1201919 A1 HK 1201919A1 HK 15102351 A HK15102351 A HK 15102351A HK 1201919 A1 HK1201919 A1 HK 1201919A1
Authority
HK
Hong Kong
Prior art keywords
tpn17
vclp15
variants
detection
vibrio cholerae
Prior art date
Application number
HK15102351.2A
Other languages
English (en)
Chinese (zh)
Inventor
Elke Faatz
Peter Schaarschmidt
Urban Schmitt
Christian Scholz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1201919A1 publication Critical patent/HK1201919A1/xx

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/35Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/20Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/28Assays involving biological materials from specific organisms or of a specific nature from bacteria from Vibrionaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/26Infectious diseases, e.g. generalised sepsis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
HK15102351.2A 2013-07-18 2015-03-09 Vibrio cholerae lipoprotein 15 (lp15) variants as anti-interference additive in tpn17-based immunoassays for detection of anti-treponema antibodies vclp15 tpn17 HK1201919A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20130003633 EP2827146A1 (en) 2013-07-18 2013-07-18 Vibrio cholerae lipoprotein 15 (Lp15) variants as anti-interference additive in TpN17-based immunoassays for detection of anti-Treponema antibodies

Publications (1)

Publication Number Publication Date
HK1201919A1 true HK1201919A1 (en) 2015-09-11

Family

ID=48874753

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102351.2A HK1201919A1 (en) 2013-07-18 2015-03-09 Vibrio cholerae lipoprotein 15 (lp15) variants as anti-interference additive in tpn17-based immunoassays for detection of anti-treponema antibodies vclp15 tpn17

Country Status (7)

Country Link
US (1) US9714949B2 (xx)
EP (2) EP2827146A1 (xx)
JP (1) JP6374720B2 (xx)
CN (1) CN104297477B (xx)
CA (1) CA2856627C (xx)
ES (1) ES2623891T3 (xx)
HK (1) HK1201919A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108780092A (zh) 2016-03-07 2018-11-09 豪夫迈·罗氏有限公司 抗p53抗体的检测
CN115112897A (zh) * 2021-12-10 2022-09-27 中山大学附属第八医院(深圳福田) 一种用于鉴别抗体检测生物学假阳性的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3827409B2 (ja) * 1997-07-07 2006-09-27 株式会社トクヤマ 免疫学的測定方法
EP2267452B8 (en) 2001-06-22 2012-11-14 Roche Diagnostics GmbH A soluble complex comprising a retroviral surface glycoprotein
DE10207135A1 (de) * 2002-02-20 2003-09-11 Euroimmun Gmbh Verfahren und Kit zum Nachweis von spezifischen Antikörpern mittels Immunfluoreszenz
CN101363860A (zh) * 2007-08-06 2009-02-11 北京科美东雅生物技术有限公司 梅毒螺旋体抗体化学发光免疫分析测定试剂盒及其制备方法
EP2127678A1 (en) * 2008-05-26 2009-12-02 Roche Diagnostics GmbH SlpA as a tool for recombinant protein and enzyme technology
CN101858915A (zh) * 2010-05-19 2010-10-13 厦门大学附属中山医院 梅毒特异性IgG抗体胶体金免疫层析检测试剂条及其制备方法

Also Published As

Publication number Publication date
CA2856627C (en) 2018-08-14
EP2827146A1 (en) 2015-01-21
EP2827147A1 (en) 2015-01-21
CA2856627A1 (en) 2015-01-18
JP2015028479A (ja) 2015-02-12
ES2623891T3 (es) 2017-07-12
CN104297477A (zh) 2015-01-21
US9714949B2 (en) 2017-07-25
EP2827147B1 (en) 2017-03-01
JP6374720B2 (ja) 2018-08-15
US20150132859A1 (en) 2015-05-14
CN104297477B (zh) 2018-07-06

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