HK1200456A1 - 用作香草素受體配體的芳基或 -雜芳基取代的甲磺酰胺衍生物 - Google Patents

用作香草素受體配體的芳基或 -雜芳基取代的甲磺酰胺衍生物

Info

Publication number
HK1200456A1
HK1200456A1 HK15101022.3A HK15101022A HK1200456A1 HK 1200456 A1 HK1200456 A1 HK 1200456A1 HK 15101022 A HK15101022 A HK 15101022A HK 1200456 A1 HK1200456 A1 HK 1200456A1
Authority
HK
Hong Kong
Prior art keywords
aryl
receptor ligands
heteroaryl substituted
vanilloid receptor
methanesulfonamide derivatives
Prior art date
Application number
HK15101022.3A
Other languages
English (en)
Inventor
Robert Frank-Foltyn
Gregor Bahrenberg
Thomas Christoph
Bernhard Lesch
Jeewoo Lee
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of HK1200456A1 publication Critical patent/HK1200456A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/06—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by carboxyl groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
HK15101022.3A 2011-09-26 2015-01-29 用作香草素受體配體的芳基或 -雜芳基取代的甲磺酰胺衍生物 HK1200456A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11007807 2011-09-26
PCT/EP2012/068877 WO2013045447A1 (en) 2011-09-26 2012-09-25 Aryl or n-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
HK1200456A1 true HK1200456A1 (zh) 2015-08-07

Family

ID=46888474

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15101022.3A HK1200456A1 (zh) 2011-09-26 2015-01-29 用作香草素受體配體的芳基或 -雜芳基取代的甲磺酰胺衍生物

Country Status (13)

Country Link
US (1) US8937092B2 (zh)
EP (1) EP2760835A1 (zh)
JP (1) JP2014531451A (zh)
KR (1) KR20140074363A (zh)
CN (1) CN103958472A (zh)
AR (1) AR088002A1 (zh)
AU (1) AU2012314587A1 (zh)
BR (1) BR112014006788A2 (zh)
CA (1) CA2849960A1 (zh)
HK (1) HK1200456A1 (zh)
MX (1) MX2014003455A (zh)
TW (1) TW201317214A (zh)
WO (1) WO2013045447A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015004035A1 (en) * 2013-07-09 2015-01-15 Lonza Ltd Method for preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2-ones from trifluoroacetylacetic acid
BR112016030358A2 (pt) 2014-06-26 2018-07-17 Lonza Ltd Método para a preparação de 4-alcóxi-1, 1, 1, trifluorobut-3-en-2-onas a partir de 1,1,1- trifluoroacetona
TW201625568A (zh) 2014-11-24 2016-07-16 歌林達有限公司 作爲類香草素受體之配位體ｉｉ之經取代以噁唑及噻唑爲主之甲醯胺及脲衍生物
EP3130589A1 (en) * 2015-08-13 2017-02-15 Grünenthal GmbH Heterocyclic aza compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135575B2 (en) 2003-03-03 2006-11-14 Array Biopharma, Inc. P38 inhibitors and methods of use thereof
JP2005314407A (ja) 2004-03-31 2005-11-10 Nippon Nohyaku Co Ltd 新規なハロアルキルスルホンアニリド誘導体、除草剤及びその使用方法並びにその中間体
EP2388258A1 (de) * 2005-10-19 2011-11-23 Grünenthal GmbH Neue Vanilloidrezeptor-Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
KR20130044382A (ko) * 2010-03-01 2013-05-02 마이렉시스 인코포레이티드 화합물 및 그의 치료 용도

Also Published As

Publication number Publication date
JP2014531451A (ja) 2014-11-27
EP2760835A1 (en) 2014-08-06
WO2013045447A1 (en) 2013-04-04
AU2012314587A1 (en) 2014-03-06
US20130079377A1 (en) 2013-03-28
BR112014006788A2 (pt) 2017-06-13
TW201317214A (zh) 2013-05-01
CA2849960A1 (en) 2013-04-04
US8937092B2 (en) 2015-01-20
AR088002A1 (es) 2014-04-30
CN103958472A (zh) 2014-07-30
KR20140074363A (ko) 2014-06-17
MX2014003455A (es) 2014-06-04

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