HK1199729A1 - Aldh-2 inhibitors in the treatment of addiction aldh-2 - Google Patents
Aldh-2 inhibitors in the treatment of addiction aldh-2Info
- Publication number
- HK1199729A1 HK1199729A1 HK15100156.3A HK15100156A HK1199729A1 HK 1199729 A1 HK1199729 A1 HK 1199729A1 HK 15100156 A HK15100156 A HK 15100156A HK 1199729 A1 HK1199729 A1 HK 1199729A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- aldh
- addiction
- inhibitors
- treatment
- addiction aldh
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Addiction (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161529164P | 2011-08-30 | 2011-08-30 | |
| PCT/US2012/053110 WO2013033377A1 (fr) | 2011-08-30 | 2012-08-30 | Inhibiteurs d'aldh-2 dans le traitement de la dépendance à des produits |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1199729A1 true HK1199729A1 (en) | 2015-07-17 |
Family
ID=46982916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15100156.3A HK1199729A1 (en) | 2011-08-30 | 2015-01-07 | Aldh-2 inhibitors in the treatment of addiction aldh-2 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8673966B2 (fr) |
| EP (1) | EP2751090A1 (fr) |
| JP (1) | JP2014525457A (fr) |
| KR (1) | KR20140057634A (fr) |
| CN (1) | CN103764640A (fr) |
| AR (1) | AR087700A1 (fr) |
| AU (1) | AU2012300209B2 (fr) |
| BR (1) | BR112014004943A2 (fr) |
| CA (1) | CA2845796A1 (fr) |
| EA (1) | EA201490270A1 (fr) |
| HK (1) | HK1199729A1 (fr) |
| IL (1) | IL230746A0 (fr) |
| MX (1) | MX2014002270A (fr) |
| TW (1) | TWI468403B (fr) |
| WO (1) | WO2013033377A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE053429T2 (hu) * | 2015-10-09 | 2021-07-28 | Univ Northwestern | (S)-3-amino-4-(difluor-metilenil)-ciklopent-l-én-l-karbonsav és rokon vegyületek, mint gaba-aminotranszferáz-inaktivátorok epilepszia, függõség és hepatocelluláris karcinóma kezelésében |
| US20230399299A1 (en) | 2022-06-14 | 2023-12-14 | Amygdala Neurosciences, Inc. | Aldh-2 inhibitor compounds and methods of use |
| WO2023244574A1 (fr) | 2022-06-14 | 2023-12-21 | Amygdala Neurosciences, Inc. | Composés inhibiteurs d'aldh-2 et procédés d'utilisation |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US4326525A (en) | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| US5364620A (en) | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US5001139A (en) | 1987-06-12 | 1991-03-19 | American Cyanamid Company | Enchancers for the transdermal flux of nivadipine |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
| US5204369A (en) | 1991-07-01 | 1993-04-20 | The Endowment For Research In Human Biology | Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse |
| US6121010A (en) | 1998-05-12 | 2000-09-19 | The Endowment For Research In Human Biology | Methods and assays useful in the treatment of alcohol dependence or alcohol abuse |
| EP1645272A3 (fr) * | 1998-05-12 | 2008-11-05 | The Endowment For Research In Human Biology, Inc. | Dérivés de daidzin pour le traitement de l'alcoolisme |
| KR20060011785A (ko) * | 2002-06-27 | 2006-02-03 | 디 인다우먼트 포 리써치 인 휴먼 바이올로지, 인크. | Ａｌｄｈ 억제에 유용한 화합물 |
| JP2007297283A (ja) | 2004-07-28 | 2007-11-15 | Santen Pharmaceut Co Ltd | 新規桂皮酸関連化合物 |
| BRPI0822129A2 (pt) * | 2008-01-24 | 2015-06-23 | Gilead Palo Alto Inc | Inibidores de aldh-2c no tratamento de vício. |
-
2012
- 2012-08-28 TW TW101131184A patent/TWI468403B/zh not_active IP Right Cessation
- 2012-08-28 AR ARP120103172A patent/AR087700A1/es unknown
- 2012-08-30 CN CN201280041692.3A patent/CN103764640A/zh active Pending
- 2012-08-30 EA EA201490270A patent/EA201490270A1/ru unknown
- 2012-08-30 BR BR112014004943A patent/BR112014004943A2/pt not_active Application Discontinuation
- 2012-08-30 JP JP2014528596A patent/JP2014525457A/ja active Pending
- 2012-08-30 WO PCT/US2012/053110 patent/WO2013033377A1/fr active Application Filing
- 2012-08-30 US US13/599,368 patent/US8673966B2/en active Active
- 2012-08-30 MX MX2014002270A patent/MX2014002270A/es not_active Application Discontinuation
- 2012-08-30 CA CA2845796A patent/CA2845796A1/fr not_active Abandoned
- 2012-08-30 EP EP12769522.9A patent/EP2751090A1/fr not_active Withdrawn
- 2012-08-30 KR KR1020147008253A patent/KR20140057634A/ko not_active Application Discontinuation
- 2012-08-30 AU AU2012300209A patent/AU2012300209B2/en not_active Ceased
-
2014
- 2014-01-30 IL IL230746A patent/IL230746A0/en unknown
-
2015
- 2015-01-07 HK HK15100156.3A patent/HK1199729A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140057634A (ko) | 2014-05-13 |
| TWI468403B (zh) | 2015-01-11 |
| CA2845796A1 (fr) | 2013-03-07 |
| TW201331197A (zh) | 2013-08-01 |
| JP2014525457A (ja) | 2014-09-29 |
| AU2012300209A1 (en) | 2013-04-04 |
| CN103764640A (zh) | 2014-04-30 |
| IL230746A0 (en) | 2014-03-31 |
| EP2751090A1 (fr) | 2014-07-09 |
| WO2013033377A1 (fr) | 2013-03-07 |
| US8673966B2 (en) | 2014-03-18 |
| AR087700A1 (es) | 2014-04-09 |
| MX2014002270A (es) | 2015-01-16 |
| EA201490270A1 (ru) | 2014-10-30 |
| US20130231325A1 (en) | 2013-09-05 |
| BR112014004943A2 (pt) | 2017-03-21 |
| AU2012300209B2 (en) | 2015-01-22 |
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