HK1198445A1 - On-column enzymatic cleavage - Google Patents

On-column enzymatic cleavage

Info

Publication number
HK1198445A1
HK1198445A1 HK14111935A HK14111935A HK1198445A1 HK 1198445 A1 HK1198445 A1 HK 1198445A1 HK 14111935 A HK14111935 A HK 14111935A HK 14111935 A HK14111935 A HK 14111935A HK 1198445 A1 HK1198445 A1 HK 1198445A1
Authority
HK
Hong Kong
Prior art keywords
enzymatic cleavage
column
column enzymatic
cleavage
enzymatic
Prior art date
Application number
HK14111935A
Other languages
English (en)
Chinese (zh)
Inventor
羅伯托．法爾肯施泰因
阿德爾伯特．格羅斯曼
弗里德里克．黑塞
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of HK1198445A1 publication Critical patent/HK1198445A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
HK14111935A 2012-02-29 2014-11-26 On-column enzymatic cleavage HK1198445A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12157510 2012-02-29
PCT/EP2013/053872 WO2013127816A1 (en) 2012-02-29 2013-02-27 On-column enzymatic cleavage

Publications (1)

Publication Number Publication Date
HK1198445A1 true HK1198445A1 (en) 2015-04-24

Family

ID=47750700

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14111935A HK1198445A1 (en) 2012-02-29 2014-11-26 On-column enzymatic cleavage

Country Status (10)

Country Link
US (1) US20150044718A1 (xx)
EP (1) EP2820031A1 (xx)
JP (1) JP2015508664A (xx)
KR (1) KR20140135959A (xx)
CN (1) CN104144939A (xx)
CA (1) CA2862820A1 (xx)
HK (1) HK1198445A1 (xx)
MX (1) MX2014010092A (xx)
RU (1) RU2014137623A (xx)
WO (1) WO2013127816A1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2014108240A (ru) 2011-08-25 2015-09-27 Ф. Хоффманн-Ля Рош Аг Укороченный тетранектин-аполипопротеин а-i гибридный белок, содержащая его липидная частица и их применения
CA2929149A1 (en) * 2013-12-20 2015-06-25 F. Hoffmann-La Roche Ag Improved recombinant polypeptide production methods
HRP20220304T1 (hr) 2015-06-24 2022-05-13 F. Hoffmann - La Roche Ag Anti-transferinska receptorska protutijela s prilagođenim afinitetom
PE20181004A1 (es) 2015-10-02 2018-06-26 Hoffmann La Roche Anticuerpos biespecificos contra el cd20 humano y el receptor de transferrina humano y metodos de uso
AR106189A1 (es) 2015-10-02 2017-12-20 Hoffmann La Roche ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
ES2824554T3 (es) * 2015-12-16 2021-05-12 Tcer Ab Plataforma de reactividad de células T
EP3573734A1 (en) * 2017-01-30 2019-12-04 Regeneron Pharmaceuticals, Inc. Method for reducing bioburden in chromatography
CN114790473A (zh) * 2021-11-08 2022-07-26 汉肽生物医药集团有限公司 一种利拉鲁肽融合蛋白在位酶切和纯化的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0422237A4 (en) 1989-03-16 1992-01-02 Nippon Kayaku Kabushiki Kaisha Liquid composition and method of dyeing therewith
SE500941C2 (sv) 1989-08-16 1994-10-03 Algy Persson Förfarande och apparat för snittning av ett preparat
BR9709569B1 (pt) * 1996-06-11 2010-05-18 processo para ativação de proteìna desnaturada.
US6291245B1 (en) 1998-07-15 2001-09-18 Roche Diagnostics Gmbh Host-vector system
EP0972838B1 (en) 1998-07-15 2004-09-15 Roche Diagnostics GmbH Escherichia coli host/vector system based on antibiotic-free selection by complementation of an auxotrophy
US6514741B1 (en) * 1999-08-18 2003-02-04 Zymogenetics, Inc. Tryptase-like polypeptide ztryp1
US6969757B2 (en) * 2001-01-26 2005-11-29 Syngenta Participations Ag Differential labeling for quantitative analysis of complex protein mixtures
WO2006009901A2 (en) * 2004-06-18 2006-01-26 Ambrx, Inc. Novel antigen-binding polypeptides and their uses
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
AU2007291501B2 (en) 2006-08-31 2012-07-12 F. Hoffmann-La Roche Ag Method for the production of insulin-like growth factor-I
WO2009034190A2 (en) * 2007-09-14 2009-03-19 Genimmune N.V. Affinity tag
US20100297734A1 (en) * 2007-10-12 2010-11-25 University Health Network Fusion Tag Comprising an Affinity Tag and an EF-Hand Motif Containing Polypeptide and Methods of Use Thereof
TW200951219A (en) * 2008-05-06 2009-12-16 Academia Sinica An improved SUMO fusion protein system for effective production of native proteins
AR082644A1 (es) 2010-08-30 2012-12-19 Hoffmann La Roche Tetranectina-apolipoproteina a-i, particulas lipidicas que la contiene y utilizacion de la misma relacionado con el metabolismo de los lipidos y las enfermedades cardiovasculares
CN103068368A (zh) 2010-08-30 2013-04-24 霍夫曼-拉罗奇有限公司 产生四连蛋白-载脂蛋白a-i脂质颗粒的方法，脂质颗粒本身及其应用

Also Published As

Publication number Publication date
US20150044718A1 (en) 2015-02-12
JP2015508664A (ja) 2015-03-23
WO2013127816A1 (en) 2013-09-06
KR20140135959A (ko) 2014-11-27
EP2820031A1 (en) 2015-01-07
CN104144939A (zh) 2014-11-12
MX2014010092A (es) 2014-09-16
RU2014137623A (ru) 2016-04-20
CA2862820A1 (en) 2013-09-06

Similar Documents

Publication Publication Date Title
HK1250690A1 (zh) 方法
HK1208363A1 (en) New methods
DK3327110T3 (en) Kassette til sterilitetstest
DK2737264T3 (en) Startlogik til kølesystem
HK1207881A1 (en) Improved enzyme variants
EP2826888B8 (en) Diaphragmless electrolyzer
ZA201500911B (en) Enzymes
HK1198445A1 (en) On-column enzymatic cleavage
GB2499683B (en) Macrospheres
GB201214938D0 (en) Alternative oxidase
GB2507760B (en) Methods
GB201320137D0 (en) Subsea Umbillical
GB201208874D0 (en) Methods
GB201207018D0 (en) Enzymes
GB201306626D0 (en) Antibacterials
EP2995681A4 (en) NOVEL DNA COLUMN ENZYME
GB201204280D0 (en) Methods
ZA201400850B (en) Enzyme system
GB201317698D0 (en) System interface
GB201208756D0 (en) Methods
GB201211978D0 (en) Enzyme
DK2700058T3 (en) Drev til internt transportsystem
GB201223308D0 (en) Enzyme inhibitors
GB201317570D0 (en) System interface
GB201207213D0 (en) Alternative oxidase