HK1192231A1 - Crystal form i of salt of a dipeptidyl peptidase-iv inhibitor and preparation method and use thereof -iv i - Google Patents

Crystal form i of salt of a dipeptidyl peptidase-iv inhibitor and preparation method and use thereof -iv i

Info

Publication number
HK1192231A1
HK1192231A1 HK14105514.0A HK14105514A HK1192231A1 HK 1192231 A1 HK1192231 A1 HK 1192231A1 HK 14105514 A HK14105514 A HK 14105514A HK 1192231 A1 HK1192231 A1 HK 1192231A1
Authority
HK
Hong Kong
Prior art keywords
inhibitor
salt
preparation
crystal form
dipeptidyl peptidase
Prior art date
Application number
HK14105514.0A
Other languages
English (en)
Chinese (zh)
Inventor
舒楚天
Original Assignee
山東軒竹醫藥科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 山東軒竹醫藥科技有限公司 filed Critical 山東軒竹醫藥科技有限公司
Publication of HK1192231A1 publication Critical patent/HK1192231A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK14105514.0A 2011-07-09 2014-06-11 Crystal form i of salt of a dipeptidyl peptidase-iv inhibitor and preparation method and use thereof -iv i HK1192231A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110202157 2011-07-09
PCT/CN2012/078294 WO2013007167A1 (zh) 2011-07-09 2012-07-06 二肽基肽酶-iv抑制剂的盐的晶型i及其制备方法和应用

Publications (1)

Publication Number Publication Date
HK1192231A1 true HK1192231A1 (en) 2014-08-15

Family

ID=47442601

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14105514.0A HK1192231A1 (en) 2011-07-09 2014-06-11 Crystal form i of salt of a dipeptidyl peptidase-iv inhibitor and preparation method and use thereof -iv i

Country Status (7)

Country Link
US (1) US8927572B2 (xx)
EP (1) EP2730575B1 (xx)
JP (1) JP5695800B2 (xx)
CN (1) CN102863440B (xx)
ES (1) ES2547687T3 (xx)
HK (1) HK1192231A1 (xx)
WO (1) WO2013007167A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017107945A1 (zh) * 2015-12-24 2017-06-29 山东轩竹医药科技有限公司 二肽基肽酶-iv抑制剂的苯甲酸盐的晶型
WO2017211293A1 (zh) * 2016-06-08 2017-12-14 山东轩竹医药科技有限公司 二肽基肽酶-iv抑制剂的丁二酸盐的晶型

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28103A1 (es) * 2002-12-03 2004-06-30 Boehringer Ingelheim Pharma Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
EP1568699A4 (en) * 2002-12-04 2007-08-15 Eisai R&D Man Co Ltd 1,3-DIHYDROIMIDAZOLE CONNECTION WITH CONDENSED RING
CN101228164A (zh) * 2005-05-20 2008-07-23 布里斯托尔-迈尔斯·斯奎布公司 二肽基肽酶iv的吡咯并吡啶类抑制剂及方法
US7521557B2 (en) * 2005-05-20 2009-04-21 Bristol-Myers Squibb Company Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
US7989469B2 (en) * 2008-02-04 2011-08-02 Cytokinetics, Incorporated Certain chemical entities, compositions, and methods
AR074072A1 (es) * 2008-11-11 2010-12-22 Lilly Co Eli Compuesto de imidazol -piperidin -pirrol-pirimidin-6-ona, composicion farmaceutica que lo comprende y su uso para preparar un medicamento util para tratar el glioblastoma multiforme
CN102127070A (zh) * 2010-01-15 2011-07-20 山东轩竹医药科技有限公司 吡啶并环衍生物

Also Published As

Publication number Publication date
EP2730575B1 (en) 2015-09-16
CN102863440B (zh) 2015-05-27
US8927572B2 (en) 2015-01-06
US20140206874A1 (en) 2014-07-24
JP5695800B2 (ja) 2015-04-08
ES2547687T3 (es) 2015-10-08
EP2730575A1 (en) 2014-05-14
CN102863440A (zh) 2013-01-09
WO2013007167A1 (zh) 2013-01-17
JP2014520763A (ja) 2014-08-25
EP2730575A4 (en) 2014-11-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190704