HK1191653A1 - -糖苷衍生物 - Google Patents
-糖苷衍生物Info
- Publication number
- HK1191653A1 HK1191653A1 HK14104952.2A HK14104952A HK1191653A1 HK 1191653 A1 HK1191653 A1 HK 1191653A1 HK 14104952 A HK14104952 A HK 14104952A HK 1191653 A1 HK1191653 A1 HK 1191653A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- glycoside derivatives
- glycoside
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/29—Saturated compounds containing keto groups bound to rings
- C07C49/327—Saturated compounds containing keto groups bound to rings containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/29—Saturated compounds containing keto groups bound to rings
- C07C49/35—Saturated compounds containing keto groups bound to rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/50—Spiro compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110188186 | 2011-06-25 | ||
| CN201110435397 | 2011-12-22 | ||
| PCT/CN2012/000868 WO2013000275A1 (zh) | 2011-06-25 | 2012-06-25 | C-糖苷衍生物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1191653A1 true HK1191653A1 (zh) | 2014-08-01 |
Family
ID=47423418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14104952.2A HK1191653A1 (zh) | 2011-06-25 | 2014-05-27 | -糖苷衍生物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9562029B2 (zh) |
| EP (1) | EP2725031B1 (zh) |
| JP (1) | JP5875678B2 (zh) |
| KR (1) | KR101719758B1 (zh) |
| CN (1) | CN102875503B (zh) |
| HK (1) | HK1191653A1 (zh) |
| WO (1) | WO2013000275A1 (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9562029B2 (en) | 2011-06-25 | 2017-02-07 | Xuanzhu Pharma Co., Ltd. | C-glycoside derivatives |
| EP2895490B1 (en) | 2013-09-27 | 2016-10-19 | Sunshine Lake Pharma Co., Ltd. | Glucopyranosyl derivatives and their uses in medicine |
| CN106349201B (zh) * | 2014-01-03 | 2018-09-18 | 山东轩竹医药科技有限公司 | 光学纯的苄基-4-氯苯基的c-糖苷衍生物 |
| ES2593050T3 (es) | 2014-01-03 | 2016-12-05 | Xuanzhu Pharma Co., Ltd. | Derivados bencil-4-clorofenil-C-glucósidos ópticamente puros como inhibidores del SGLT (diabetes mellitus) |
| US9315438B2 (en) | 2014-01-03 | 2016-04-19 | Xuanzhu Pharma Co., Ltd | Optically pure benzyl-4-chlorophenyl-C-glucoside derivative |
| CN105017236A (zh) * | 2014-04-14 | 2015-11-04 | 上海迪诺医药科技有限公司 | C-芳基糖苷衍生物、其药物组合物、制备方法及应用 |
| CN105001213B (zh) * | 2014-04-14 | 2020-08-28 | 上海迪诺医药科技有限公司 | C-芳基糖苷衍生物、其药物组合物、制备方法及应用 |
| KR101721914B1 (ko) | 2015-07-13 | 2017-04-03 | 한국항공우주연구원 | 접이식이동카트를 설치한 운송컨테이너 |
| US11081647B2 (en) * | 2016-04-22 | 2021-08-03 | Universal Display Corporation | Organic electroluminescent materials and devices |
| EP3466940B1 (en) | 2016-05-28 | 2021-11-17 | Ji Lin Hui Sheng Bio-Pharmaceutical Co., Ltd. | Crystal form of sodium-glucose cotransporter 2 inhibitor |
| WO2019185026A1 (zh) * | 2018-03-30 | 2019-10-03 | 南京明德新药研发有限公司 | 作为SGLTs抑制剂的葡糖苷类衍生物及其应用 |
| CN110551088B (zh) * | 2018-06-01 | 2022-10-21 | 北京惠之衡生物科技有限公司 | 氘修饰的苄基-4-氯苯基的c-糖苷衍生物 |
| CN113248554A (zh) * | 2021-06-25 | 2021-08-13 | 北京惠之衡生物科技有限公司 | 一种c-糖苷类衍生物的杂质的合成方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5558287A (en) | 1995-02-02 | 1996-09-24 | Lucent Technologies Inc. | Apparatus and method to prevent flailing damage to a strand wound on a spool |
| JP3820037B2 (ja) | 1998-11-05 | 2006-09-13 | 三井化学株式会社 | 光記録媒体 |
| US7375125B2 (en) * | 1999-08-04 | 2008-05-20 | Ore Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
| US6515117B2 (en) | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
| PH12000002657B1 (en) * | 1999-10-12 | 2006-02-21 | Bristol Myers Squibb Co | C-aryl glucoside SGLT2 inhibitors |
| WO2003035650A1 (fr) * | 2001-09-25 | 2003-05-01 | Takeda Chemical Industries, Ltd. | Inhibiteur d'entree |
| JP4651934B2 (ja) * | 2002-12-04 | 2011-03-16 | キッセイ薬品工業株式会社 | ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途 |
| BR0317929A (pt) | 2003-01-03 | 2006-04-11 | Bristol Myers Squibb Co | métodos de produzir inibidores de sglt2 de glicosìdeo de c-arila |
| JP2004300102A (ja) | 2003-03-31 | 2004-10-28 | Kissei Pharmaceut Co Ltd | 縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途 |
| US7829204B2 (en) | 2003-12-15 | 2010-11-09 | Idemitsu Kosan Co., Ltd. | Material for organic electroluminescent device and organic electroluminescent device using same |
| NZ550464A (en) * | 2004-03-16 | 2010-10-29 | Boehringer Ingelheim Int | Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof |
| DE102004012676A1 (de) | 2004-03-16 | 2005-10-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Glucopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
| EA200801773A1 (ru) | 2006-02-15 | 2009-02-27 | Бёрингер Ингельхайм Интернациональ Гмбх | Глюкопиранозилзамещенные производные бензонитрила, фармацевтические композиции, содержащие такие соединения, их применение и способ их получения |
| WO2007136116A2 (en) | 2006-05-19 | 2007-11-29 | Taisho Pharmaceutical Co., Ltd. | C-phenyl glycitol compound for the treatment of diabetes |
| TW200846441A (en) * | 2007-05-17 | 2008-12-01 | Tetrahedron Technology Corp | Fluorescence main host material and organic electroluminescence device using the material |
| WO2009026537A1 (en) | 2007-08-23 | 2009-02-26 | Theracos, Inc. | Benzylbenzene derivatives and methods of use |
| US8420234B2 (en) * | 2009-01-06 | 2013-04-16 | Udc Ireland Limited | Organic electroluminescent device |
| WO2010147430A2 (en) * | 2009-06-19 | 2010-12-23 | Green Cross Corporation | Novel c-aryl glucoside sglt2 inhibitors and pharmaceutical composition comprising same |
| KR20110065978A (ko) * | 2009-12-10 | 2011-06-16 | 엘지디스플레이 주식회사 | 적색 인광 호스트 화합물 및 이를 사용한 유기전계발광소자 |
| CN102803226B (zh) | 2010-03-18 | 2016-05-04 | 第一三共株式会社 | 环烷基取代的咪唑衍生物 |
| WO2012025857A1 (en) | 2010-08-23 | 2012-03-01 | Hetero Research Foundation | Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors |
| US9562029B2 (en) | 2011-06-25 | 2017-02-07 | Xuanzhu Pharma Co., Ltd. | C-glycoside derivatives |
| US9315438B2 (en) | 2014-01-03 | 2016-04-19 | Xuanzhu Pharma Co., Ltd | Optically pure benzyl-4-chlorophenyl-C-glucoside derivative |
-
2012
- 2012-06-25 US US14/129,316 patent/US9562029B2/en active Active
- 2012-06-25 KR KR1020147002034A patent/KR101719758B1/ko active IP Right Grant
- 2012-06-25 EP EP12805011.9A patent/EP2725031B1/en active Active
- 2012-06-25 JP JP2014517397A patent/JP5875678B2/ja active Active
- 2012-06-25 CN CN201210212402.9A patent/CN102875503B/zh active Active
- 2012-06-25 WO PCT/CN2012/000868 patent/WO2013000275A1/zh active Application Filing
-
2014
- 2014-05-27 HK HK14104952.2A patent/HK1191653A1/zh unknown
-
2016
- 2016-12-19 US US15/383,885 patent/US10253010B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014520163A (ja) | 2014-08-21 |
| EP2725031B1 (en) | 2016-08-03 |
| KR20140057527A (ko) | 2014-05-13 |
| JP5875678B2 (ja) | 2016-03-02 |
| US10253010B2 (en) | 2019-04-09 |
| US20140128331A1 (en) | 2014-05-08 |
| EP2725031A1 (en) | 2014-04-30 |
| CN102875503A (zh) | 2013-01-16 |
| WO2013000275A1 (zh) | 2013-01-03 |
| US9562029B2 (en) | 2017-02-07 |
| US20170101388A1 (en) | 2017-04-13 |
| EP2725031A4 (en) | 2014-12-03 |
| KR101719758B1 (ko) | 2017-03-24 |
| CN102875503B (zh) | 2016-05-25 |
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