HK1187554A1 - 阿瑞匹坦 -脯氨酸組合物和共晶 - Google Patents
阿瑞匹坦 -脯氨酸組合物和共晶Info
- Publication number
- HK1187554A1 HK1187554A1 HK14100748.9A HK14100748A HK1187554A1 HK 1187554 A1 HK1187554 A1 HK 1187554A1 HK 14100748 A HK14100748 A HK 14100748A HK 1187554 A1 HK1187554 A1 HK 1187554A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cocrystal
- aprepitant
- proline composition
- proline
- composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38574410P | 2010-09-23 | 2010-09-23 | |
| US201161439654P | 2011-02-04 | 2011-02-04 | |
| US201161498214P | 2011-06-17 | 2011-06-17 | |
| PCT/IB2011/054210 WO2012038937A1 (en) | 2010-09-23 | 2011-09-23 | Aprepitant l-proline composition and cocrystal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1187554A1 true HK1187554A1 (zh) | 2014-04-11 |
Family
ID=44907915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14100748.9A HK1187554A1 (zh) | 2010-09-23 | 2014-01-23 | 阿瑞匹坦 -脯氨酸組合物和共晶 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9029369B2 (zh) |
| EP (1) | EP2618828B1 (zh) |
| JP (1) | JP5997162B2 (zh) |
| KR (1) | KR101833578B1 (zh) |
| CN (1) | CN103221049B (zh) |
| AR (1) | AR083095A1 (zh) |
| AU (1) | AU2011306391B2 (zh) |
| BR (1) | BR112013006651A2 (zh) |
| CA (1) | CA2846460C (zh) |
| ES (1) | ES2616752T3 (zh) |
| HK (1) | HK1187554A1 (zh) |
| IL (1) | IL225443A0 (zh) |
| TW (1) | TWI540131B (zh) |
| WO (1) | WO2012038937A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013006651A2 (pt) | 2010-09-23 | 2017-07-18 | Nuformix Ltd | composição e cocristal de aprepitante l-prolina |
| JP6178799B2 (ja) * | 2011-11-25 | 2017-08-09 | ナフォーミックス リミテッド | アプレピタントｌ−プロリン溶媒和化合物−組成物及び共結晶 |
| US10098859B2 (en) | 2012-09-05 | 2018-10-16 | Amri Ssci, Llc | Cocrystals of p-coumaric acid |
| US20160324881A1 (en) * | 2013-12-30 | 2016-11-10 | Oncoprevent Gmbh | Neurokinin-1 Receptor Antagonists For Use In A Method Of Prevention Of Cancer |
| BR112020016205A2 (pt) | 2018-02-07 | 2020-12-15 | Reata Pharmaceuticals, Inc. | Formas cocristalinas de prolina e de análogo de novobiocina |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US5719147A (en) | 1992-06-29 | 1998-02-17 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
| US6048859A (en) | 1992-06-29 | 2000-04-11 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
| IL111960A (en) | 1993-12-17 | 1999-12-22 | Merck & Co Inc | Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them |
| ZA985765B (en) | 1997-07-02 | 1999-08-04 | Merck & Co Inc | Polymorphic form of a tachykinin receptor antagonist. |
| US20050025791A1 (en) | 2002-06-21 | 2005-02-03 | Julius Remenar | Pharmaceutical compositions with improved dissolution |
| EP1608339B8 (en) * | 2003-02-28 | 2012-04-25 | McNeill-PPC, Inc. | Pharmaceutical co-crystal of celecoxib-nicotinamide |
| EP2034952A4 (en) * | 2006-06-16 | 2011-08-17 | Reddys Lab Ltd Dr | APREPITANT COMPOSITIONS |
| WO2009108828A2 (en) * | 2008-02-27 | 2009-09-03 | Dr. Reddy's Laboratories Ltd. | Solubility-enhanced forms of aprepitant and pharmaceutical compositions thereof |
| BR112013006651A2 (pt) | 2010-09-23 | 2017-07-18 | Nuformix Ltd | composição e cocristal de aprepitante l-prolina |
-
2011
- 2011-09-23 BR BR112013006651A patent/BR112013006651A2/pt not_active Application Discontinuation
- 2011-09-23 JP JP2013529758A patent/JP5997162B2/ja active Active
- 2011-09-23 WO PCT/IB2011/054210 patent/WO2012038937A1/en active Application Filing
- 2011-09-23 CN CN201180055997.5A patent/CN103221049B/zh active Active
- 2011-09-23 EP EP11779217.6A patent/EP2618828B1/en active Active
- 2011-09-23 KR KR1020137010228A patent/KR101833578B1/ko active IP Right Grant
- 2011-09-23 US US13/825,380 patent/US9029369B2/en active Active
- 2011-09-23 TW TW100134362A patent/TWI540131B/zh active
- 2011-09-23 AR ARP110103486 patent/AR083095A1/es unknown
- 2011-09-23 CA CA2846460A patent/CA2846460C/en active Active
- 2011-09-23 ES ES11779217.6T patent/ES2616752T3/es active Active
- 2011-09-23 AU AU2011306391A patent/AU2011306391B2/en active Active
-
2013
- 2013-03-21 IL IL225443A patent/IL225443A0/en active IP Right Grant
-
2014
- 2014-01-23 HK HK14100748.9A patent/HK1187554A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TWI540131B (zh) | 2016-07-01 |
| KR20140040671A (ko) | 2014-04-03 |
| US20130252949A1 (en) | 2013-09-26 |
| JP2013537901A (ja) | 2013-10-07 |
| CN103221049B (zh) | 2015-11-25 |
| EP2618828A1 (en) | 2013-07-31 |
| BR112013006651A2 (pt) | 2017-07-18 |
| WO2012038937A1 (en) | 2012-03-29 |
| CN103221049A (zh) | 2013-07-24 |
| IL225443A0 (en) | 2013-06-27 |
| JP5997162B2 (ja) | 2016-09-28 |
| AR083095A1 (es) | 2013-01-30 |
| ES2616752T3 (es) | 2017-06-14 |
| US9029369B2 (en) | 2015-05-12 |
| KR101833578B1 (ko) | 2018-02-28 |
| EP2618828B1 (en) | 2016-11-23 |
| CA2846460A1 (en) | 2012-03-29 |
| AU2011306391B2 (en) | 2016-12-15 |
| AU2011306391A1 (en) | 2013-04-11 |
| CA2846460C (en) | 2019-01-08 |
| TW201217366A (en) | 2012-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB201002983D0 (en) | Nutritinal composition | |
| GB201006699D0 (en) | Composition | |
| GB201021186D0 (en) | Composition | |
| EP2568007A4 (en) | FLUOR RUBBER COMPOSITION | |
| HK1184077A1 (zh) | 牙科組合物 | |
| ZA201302113B (en) | Caspofungin composition | |
| GB201006178D0 (en) | Composition | |
| HK1185815A1 (zh) | 牙科組合物 | |
| GB201021269D0 (en) | Composition | |
| HK1187554A1 (zh) | 阿瑞匹坦 -脯氨酸組合物和共晶 | |
| GB201017048D0 (en) | Composition | |
| PL2625258T3 (pl) | Kompozycja do czyszczenia z polimerów | |
| GB201019988D0 (en) | Composition | |
| GB201016970D0 (en) | Composition | |
| GB201005927D0 (en) | Improved composition | |
| GB201007531D0 (en) | Composition | |
| GB201006214D0 (en) | Composition | |
| ZA201303199B (en) | Herbicicdal composition | |
| GB201006204D0 (en) | Composition | |
| GB201004717D0 (en) | Composition | |
| ZA201104385B (en) | Improved combustible composition | |
| GB201010657D0 (en) | Composition | |
| GB201006175D0 (en) | Composition | |
| PL2534235T3 (pl) | Kompozycja | |
| GB201018130D0 (en) | Composition |