HK1183867A1 - Benzazole derivatives as histamine h4 receptor ligands h4 - Google Patents

Benzazole derivatives as histamine h4 receptor ligands h4

Info

Publication number
HK1183867A1
HK1183867A1 HK13111288.3A HK13111288A HK1183867A1 HK 1183867 A1 HK1183867 A1 HK 1183867A1 HK 13111288 A HK13111288 A HK 13111288A HK 1183867 A1 HK1183867 A1 HK 1183867A1
Authority
HK
Hong Kong
Prior art keywords
histamine
receptor ligands
benzazole derivatives
benzazole
derivatives
Prior art date
Application number
HK13111288.3A
Other languages
English (en)
Chinese (zh)
Inventor
Isabelle Berrebi-Bertrand
Xavier Billot
Thierry Calmels
Marc Capet
Denis Danvy
Stphane Krief
Olivier Labeeuw
Jeanne-Marie Lecomte
Nicolas Levoin
Xavier Ligneau
Philippe Robert
Jean-Charles Schwartz
Original Assignee
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet Soc Civ filed Critical Bioprojet Soc Civ
Publication of HK1183867A1 publication Critical patent/HK1183867A1/xx

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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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HK13111288.3A 2010-09-27 2013-10-04 Benzazole derivatives as histamine h4 receptor ligands h4 HK1183867A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20100306038 EP2447263A1 (en) 2010-09-27 2010-09-27 Benzazole derivatives as histamine H4 receptor ligands
PCT/EP2011/066782 WO2012041860A1 (en) 2010-09-27 2011-09-27 Benzazole derivatives as histamine h4 receptor ligands

Publications (1)

Publication Number Publication Date
HK1183867A1 true HK1183867A1 (en) 2014-01-10

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HK13111288.3A HK1183867A1 (en) 2010-09-27 2013-10-04 Benzazole derivatives as histamine h4 receptor ligands h4

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US (2) US8802664B2 (hr)
EP (2) EP2447263A1 (hr)
JP (1) JP5922128B2 (hr)
CN (1) CN103228643B (hr)
CA (1) CA2812686C (hr)
CY (1) CY1117416T1 (hr)
DK (1) DK2621916T3 (hr)
ES (1) ES2571335T3 (hr)
HK (1) HK1183867A1 (hr)
HR (1) HRP20160398T1 (hr)
HU (1) HUE027252T2 (hr)
MX (1) MX339460B (hr)
PL (1) PL2621916T3 (hr)
RS (1) RS54737B1 (hr)
SI (1) SI2621916T1 (hr)
SM (1) SMT201600262B (hr)
WO (1) WO2012041860A1 (hr)

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WO2012143131A1 (en) 2011-04-19 2012-10-26 Saudi Basic Industries Corporation Carbon supported cobalt and molybdenum catalyst
PT2855456T (pt) * 2012-05-04 2017-07-10 Novartis Ag Moduladores da via do complemento e usos dos mesmos
EP2671870A1 (en) * 2012-06-05 2013-12-11 Bioprojet Novel (aza)benzhydryl ether derivatives, their process of preparation and their use as H4-receptor ligands for therapeutical applications
HUE039713T2 (hu) 2012-06-08 2019-02-28 Sensorion H4 receptor inhibitorok tinnitus kezelésére
CN106800524A (zh) * 2015-02-13 2017-06-06 佛山市赛维斯医药科技有限公司 一类含双酰肼和萘基结构的化合物、制备方法及其用途
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