HK1176928A1 - 作為 抑制劑的取代 -吲唑- -基 咪唑並 吡啶- -羧酰胺化合物 - Google Patents

作為 抑制劑的取代 -吲唑- -基 咪唑並 吡啶- -羧酰胺化合物

Info

Publication number
HK1176928A1
HK1176928A1 HK13103717.1A HK13103717A HK1176928A1 HK 1176928 A1 HK1176928 A1 HK 1176928A1 HK 13103717 A HK13103717 A HK 13103717A HK 1176928 A1 HK1176928 A1 HK 1176928A1
Authority
HK
Hong Kong
Prior art keywords
cfms
indazol
imidazo
pyridine
substituted
Prior art date
Application number
HK13103717.1A
Other languages
English (en)
Inventor
Mark Laurence Boys
Michael F Bradley
Robert Kirk Delisle
D David Hennings
April L Kennedy
Fredrik P Marmsater
Matthew David Medina
Mark C Munson
Bryson Rast
James P Rizzi
Martha E Rodriguez
George T Topalov
Qian Zhao
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of HK1176928A1 publication Critical patent/HK1176928A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
HK13103717.1A 2009-12-21 2013-03-25 作為 抑制劑的取代 -吲唑- -基 咪唑並 吡啶- -羧酰胺化合物 HK1176928A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28872909P 2009-12-21 2009-12-21
PCT/US2010/061341 WO2011079076A1 (en) 2009-12-21 2010-12-20 Substituted n-(1h-indazol-4-yl)imidazo[1, 2-a]pyridine-3- carboxamide compounds as cfms inhibitors

Publications (1)

Publication Number Publication Date
HK1176928A1 true HK1176928A1 (zh) 2013-08-09

Family

ID=43568700

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13103717.1A HK1176928A1 (zh) 2009-12-21 2013-03-25 作為 抑制劑的取代 -吲唑- -基 咪唑並 吡啶- -羧酰胺化合物

Country Status (32)

Country Link
US (1) US8841455B2 (zh)
EP (1) EP2516433B1 (zh)
JP (2) JP5739448B2 (zh)
KR (1) KR101779630B1 (zh)
CN (1) CN102822170B (zh)
AR (1) AR079541A1 (zh)
AU (1) AU2010333752B2 (zh)
BR (1) BR112012017123B1 (zh)
CA (1) CA2785338C (zh)
CL (1) CL2012001699A1 (zh)
CO (1) CO6561821A2 (zh)
CR (1) CR20120389A (zh)
DK (1) DK2516433T3 (zh)
ES (1) ES2494590T3 (zh)
HK (1) HK1176928A1 (zh)
HR (1) HRP20140770T1 (zh)
IL (1) IL220544A (zh)
ME (1) ME01894B (zh)
MX (1) MX2012007329A (zh)
MY (1) MY163791A (zh)
NZ (1) NZ601376A (zh)
PL (1) PL2516433T3 (zh)
PT (1) PT2516433E (zh)
RS (1) RS53500B1 (zh)
RU (1) RU2562977C2 (zh)
SG (1) SG181861A1 (zh)
SI (1) SI2516433T1 (zh)
SM (1) SMT201400142B (zh)
TW (1) TWI471326B (zh)
UA (1) UA108222C2 (zh)
WO (1) WO2011079076A1 (zh)
ZA (1) ZA201205505B (zh)

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PL3001903T3 (pl) 2009-12-21 2018-03-30 Samumed, Llc 1H-pirazolo[3,4-b]pirydyny i ich zastosowania terapeutyczne
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WO2016040184A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040182A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
KR20170096187A (ko) 2014-12-22 2017-08-23 파이브 프라임 테라퓨틱스, 인크. Pvns를 치료하기 위한 항-csf1r 항체
CN204833440U (zh) 2015-07-29 2015-12-02 山东新北洋信息技术股份有限公司 识读组件及纸币清分机
US10350199B2 (en) 2015-08-03 2019-07-16 Samumed, Llc 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
US10206909B2 (en) 2015-08-03 2019-02-19 Samumed, Llc 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
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Also Published As

Publication number Publication date
RU2012131129A (ru) 2014-01-27
SG181861A1 (en) 2012-07-30
IL220544A0 (en) 2012-08-30
ES2494590T3 (es) 2014-09-15
CO6561821A2 (es) 2012-11-15
UA108222C2 (xx) 2015-04-10
BR112012017123B1 (pt) 2021-07-20
JP2015107999A (ja) 2015-06-11
EP2516433B1 (en) 2014-05-21
KR101779630B1 (ko) 2017-09-18
CN102822170B (zh) 2014-12-10
IL220544A (en) 2016-05-31
CL2012001699A1 (es) 2013-02-01
US8841455B2 (en) 2014-09-23
MX2012007329A (es) 2012-10-15
BR112012017123A2 (pt) 2017-10-31
PL2516433T3 (pl) 2014-10-31
CN102822170A (zh) 2012-12-12
MY163791A (en) 2017-10-31
AU2010333752B2 (en) 2014-12-04
AU2010333752A2 (en) 2012-09-06
PT2516433E (pt) 2014-09-03
SMT201400142B (it) 2014-11-10
ME01894B (me) 2014-12-20
JP5739448B2 (ja) 2015-06-24
WO2011079076A1 (en) 2011-06-30
AU2010333752A1 (en) 2012-08-09
SI2516433T1 (sl) 2014-09-30
AR079541A1 (es) 2012-02-01
EP2516433A1 (en) 2012-10-31
KR20120106853A (ko) 2012-09-26
CA2785338A1 (en) 2011-06-30
RS53500B1 (en) 2015-02-27
CR20120389A (es) 2012-08-16
CA2785338C (en) 2018-09-18
JP2013515070A (ja) 2013-05-02
US20120258952A1 (en) 2012-10-11
ZA201205505B (en) 2013-04-24
NZ601376A (en) 2014-03-28
DK2516433T3 (da) 2014-08-11
HRP20140770T1 (hr) 2014-11-07
TWI471326B (zh) 2015-02-01
TW201121973A (en) 2011-07-01
RU2562977C2 (ru) 2015-09-10

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