HK1174044A1 - Chromatographic method for purifying fc-containing proteins fc - Google Patents

Chromatographic method for purifying fc-containing proteins fc

Info

Publication number
HK1174044A1
HK1174044A1 HK13101026.1A HK13101026A HK1174044A1 HK 1174044 A1 HK1174044 A1 HK 1174044A1 HK 13101026 A HK13101026 A HK 13101026A HK 1174044 A1 HK1174044 A1 HK 1174044A1
Authority
HK
Hong Kong
Prior art keywords
purifying
containing proteins
chromatographic method
chromatographic
proteins
Prior art date
Application number
HK13101026.1A
Other languages
English (en)
Chinese (zh)
Inventor
Christian Eckermann
Dorothee Ambrosius
Franz Nothelfer
Thomas Rathjen
Original Assignee
貝林格爾‧英格海姆國際有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 貝林格爾‧英格海姆國際有限公司 filed Critical 貝林格爾‧英格海姆國際有限公司
Publication of HK1174044A1 publication Critical patent/HK1174044A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
HK13101026.1A 2010-01-22 2013-01-23 Chromatographic method for purifying fc-containing proteins fc HK1174044A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10151416 2010-01-22
EP10171975 2010-08-05
PCT/EP2011/050817 WO2011089212A1 (de) 2010-01-22 2011-01-21 Chromatographisches verfahren zur aufreinigung von fc enthaltenden proteinen

Publications (1)

Publication Number Publication Date
HK1174044A1 true HK1174044A1 (en) 2013-05-31

Family

ID=43598239

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13101026.1A HK1174044A1 (en) 2010-01-22 2013-01-23 Chromatographic method for purifying fc-containing proteins fc

Country Status (12)

Country Link
US (1) US9284347B2 (es)
EP (1) EP2526114B1 (es)
JP (1) JP5567691B2 (es)
KR (1) KR101753569B1 (es)
CN (1) CN102712673B (es)
AU (1) AU2011208659B2 (es)
CA (1) CA2784959C (es)
DK (1) DK2526114T3 (es)
ES (1) ES2492681T3 (es)
HK (1) HK1174044A1 (es)
SG (1) SG182553A1 (es)
WO (1) WO2011089212A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ602971A (en) * 2010-04-23 2014-11-28 Serum Inst India Ltd Simple method for simultaneous removal of multiple impurities from culture supernatants to ultralow levels
CA2834300C (en) * 2011-06-01 2022-01-11 Novartis Ag Wash solution and method for affinity chromatography
RU2646098C2 (ru) 2013-04-30 2018-03-01 Интас Фармасьютикалс Лтд Новый способ клонирования, экспрессии и очистки для получения ранибизумаба
AR096713A1 (es) 2013-06-25 2016-01-27 Cadila Healthcare Ltd Proceso de purificación para anticuerpos monoclonales
BR112016029157A8 (pt) * 2014-06-13 2021-07-06 Lupin Ltd processo para purificar a proteína de fusão tnfr:fc
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
AU2015372801B2 (en) 2014-12-31 2018-12-20 Lg Chem, Ltd. Method for preparing tnfr-fc fusion protein containing target content of impurities
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US11753438B2 (en) 2016-05-11 2023-09-12 Cytiva Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
WO2017194592A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of storing a separation matrix
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
WO2019096777A1 (en) * 2017-11-14 2019-05-23 Bio-Sourcing S.A. Antibody purification
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
CN113166200B (zh) * 2018-12-21 2024-03-01 上海药明生物技术有限公司 一种提高蛋白a层析法去除聚集体的方法
CN111333776B (zh) * 2020-03-20 2021-11-09 暨南大学 一种氮杂环类有机聚合物整体材料及制备与应用
WO2024017826A2 (en) * 2022-07-19 2024-01-25 Glaxosmithkline Intellectual Property Development Limited Methods for purifying recombinant polypeptides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874218A (en) * 1990-06-11 1999-02-23 Nexstar Pharmaceuticals, Inc. Method for detecting a target compound in a substance using a nucleic acid ligand
US5585246A (en) * 1993-02-17 1996-12-17 Biometric Imaging, Inc. Method for preparing a sample in a scan capillary for immunofluorescent interrogation
ATE417858T1 (de) 2002-02-05 2009-01-15 Genentech Inc Proteinaufreinigung
US8084032B2 (en) * 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
WO2007059473A2 (en) * 2005-11-12 2007-05-24 Introgen Therapeutics, Inc. Methods for the production and purification of adenoviral vectors
AU2007204987B2 (en) 2006-01-06 2011-11-24 Amgen Inc. Methods and systems for isolating target molecules from complex solutions by column-chromatography using eluants containing organic solvents
US8263750B2 (en) 2006-03-16 2012-09-11 Amgen Inc. Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step
TW200821026A (en) * 2006-09-08 2008-05-16 Wyeth Corp Arginine wash in protein purification using affinity chromatography
CA2751000A1 (en) * 2009-03-11 2010-12-23 Wyeth Llc Methods of purifying small modular immunopharmaceutical proteins
WO2011073389A1 (en) 2009-12-18 2011-06-23 Novartis Ag Wash solution and method for affinity chromatography

Also Published As

Publication number Publication date
JP5567691B2 (ja) 2014-08-06
KR20120118013A (ko) 2012-10-25
DK2526114T3 (da) 2014-09-29
EP2526114A1 (de) 2012-11-28
ES2492681T3 (es) 2014-09-10
CN102712673B (zh) 2014-04-30
CA2784959C (en) 2018-06-26
JP2013517318A (ja) 2013-05-16
US20130197197A1 (en) 2013-08-01
AU2011208659B2 (en) 2015-05-28
WO2011089212A1 (de) 2011-07-28
SG182553A1 (en) 2012-08-30
CA2784959A1 (en) 2011-07-28
AU2011208659A1 (en) 2012-07-19
KR101753569B1 (ko) 2017-07-04
CN102712673A (zh) 2012-10-03
US9284347B2 (en) 2016-03-15
EP2526114B1 (de) 2014-06-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190124