HK1171689A1 - 核酸轉運用載體組合物 - Google Patents

核酸轉運用載體組合物

Info

Publication number
HK1171689A1
HK1171689A1 HK12112608.5A HK12112608A HK1171689A1 HK 1171689 A1 HK1171689 A1 HK 1171689A1 HK 12112608 A HK12112608 A HK 12112608A HK 1171689 A1 HK1171689 A1 HK 1171689A1
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
carrier composition
acid transport
transport
carrier
Prior art date
Application number
HK12112608.5A
Other languages
English (en)
Inventor
豐福秀
宮尾英男
佐藤正子
關口和生
Original Assignee
大塚製藥株式會社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 大塚製藥株式會社 filed Critical 大塚製藥株式會社
Publication of HK1171689A1 publication Critical patent/HK1171689A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
HK12112608.5A 2005-10-18 2012-12-06 核酸轉運用載體組合物 HK1171689A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005303497 2005-10-18

Publications (1)

Publication Number Publication Date
HK1171689A1 true HK1171689A1 (zh) 2013-04-05

Family

ID=37962449

Family Applications (2)

Application Number Title Priority Date Filing Date
HK08114132.2A HK1119956A1 (en) 2005-10-18 2008-12-31 Carrier composition for nucleic acid transport
HK12112608.5A HK1171689A1 (zh) 2005-10-18 2012-12-06 核酸轉運用載體組合物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK08114132.2A HK1119956A1 (en) 2005-10-18 2008-12-31 Carrier composition for nucleic acid transport

Country Status (20)

Country Link
US (1) US8030075B2 (zh)
EP (1) EP1946761B8 (zh)
JP (1) JP5046952B2 (zh)
KR (1) KR101324065B1 (zh)
CN (2) CN102512689B (zh)
AR (1) AR057553A1 (zh)
AU (1) AU2006305318B2 (zh)
BR (1) BRPI0617449A2 (zh)
CA (1) CA2624840A1 (zh)
CY (1) CY1114586T1 (zh)
DK (1) DK1946761T3 (zh)
ES (1) ES2412029T3 (zh)
HK (2) HK1119956A1 (zh)
MY (1) MY149502A (zh)
PL (1) PL1946761T3 (zh)
PT (1) PT1946761E (zh)
RU (1) RU2421227C2 (zh)
SI (1) SI1946761T1 (zh)
TW (1) TW200800235A (zh)
WO (1) WO2007046356A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200800235A (en) * 2005-10-18 2008-01-01 Otsuka Pharma Co Ltd Carrier composition for nucleic acid transport
US20110200582A1 (en) 2009-12-23 2011-08-18 Novartis Ag Lipids, lipid compositions, and methods of using them
WO2011114678A1 (ja) * 2010-03-15 2011-09-22 国立大学法人山口大学 哺乳動物細胞への遺伝子導入効率の向上剤
EP2852380A4 (en) * 2012-05-23 2016-01-20 Univ Ohio State LIPID-COATED ALBUMIN NANOPARTICLE COMPOSITIONS AND METHOD FOR THE PREPARATION AND METHOD OF USE THEREOF
US9833416B2 (en) * 2014-04-04 2017-12-05 Ohio State Innovation Foundation Oligonucleotide lipid nanoparticle compositions, methods of making and methods of using the same
US20180355345A1 (en) * 2015-07-30 2018-12-13 Arcis Biotechnology Holdings Limited Method and composition

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030092180A1 (en) 2001-08-27 2003-05-15 David Lewis Inhibition of gene expression by delivery of small interfering RNA to post-embryonic animal cells in vivo
US5965542A (en) * 1997-03-18 1999-10-12 Inex Pharmaceuticals Corp. Use of temperature to control the size of cationic liposome/plasmid DNA complexes
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
EP1829856A3 (en) * 1998-11-12 2009-02-25 Invitrogen Corporation Transfection reagents
ATE354350T1 (de) * 2000-10-25 2007-03-15 Univ British Columbia Lipidformulierungen zur zielgerichteten abgabe
EP1355628A2 (en) * 2001-02-01 2003-10-29 Board of Regents, The University of Texas System Stabilised polymeric aerosols for pulmonary gene delivery
US20030096414A1 (en) * 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection
US7713942B2 (en) * 2001-04-04 2010-05-11 Nordic Vaccine Technology A/S Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
EP1575976A4 (en) * 2001-11-02 2006-08-23 Insert Therapeutics Inc METHODS AND COMPOSITIONS FOR THE THERAPEUTIC USE OF RNA INTERFERENCE
RU2311911C2 (ru) * 2002-07-05 2007-12-10 Липоксен Текнолоджиз Лимитед Способ усиления иммунного ответа при вакцинации нуклеиновой кислотой
ES2559828T3 (es) * 2003-07-16 2016-02-16 Protiva Biotherapeutics Inc. ARN de interferencia encapsulado en lípidos
EP1812016A4 (en) 2004-11-17 2010-07-14 Univ Maryland HIGHLY BRANCHED HK PEPTIDES AS EFFECTIVE CARRIERS OF SMALL INTERFERING RNA
US20070087045A1 (en) * 2005-10-14 2007-04-19 Industrial Technology Research Institute Lipid carrier and method of preparing the same
TW200800235A (en) * 2005-10-18 2008-01-01 Otsuka Pharma Co Ltd Carrier composition for nucleic acid transport

Also Published As

Publication number Publication date
US20090258923A1 (en) 2009-10-15
CN102512689A (zh) 2012-06-27
AU2006305318A1 (en) 2007-04-26
JP5046952B2 (ja) 2012-10-10
CN101291678B (zh) 2012-03-28
EP1946761A4 (en) 2012-01-25
RU2421227C2 (ru) 2011-06-20
KR101324065B1 (ko) 2013-10-31
WO2007046356A1 (ja) 2007-04-26
CA2624840A1 (en) 2007-04-26
TW200800235A (en) 2008-01-01
US8030075B2 (en) 2011-10-04
PL1946761T3 (pl) 2013-08-30
CN102512689B (zh) 2014-08-20
TWI376225B (zh) 2012-11-11
MY149502A (en) 2013-09-13
CY1114586T1 (el) 2016-10-05
DK1946761T3 (da) 2013-04-15
RU2008119498A (ru) 2009-11-27
ES2412029T3 (es) 2013-07-09
PT1946761E (pt) 2013-05-27
AR057553A1 (es) 2007-12-05
EP1946761B8 (en) 2013-05-22
AU2006305318B2 (en) 2011-08-25
KR20080059648A (ko) 2008-06-30
EP1946761B1 (en) 2013-04-03
EP1946761A1 (en) 2008-07-23
SI1946761T1 (sl) 2013-06-28
BRPI0617449A2 (pt) 2011-07-26
CN101291678A (zh) 2008-10-22
JPWO2007046356A1 (ja) 2009-04-23
HK1119956A1 (en) 2009-03-20

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181017