HK1171261A1 - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents

Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Info

Publication number
HK1171261A1
HK1171261A1 HK12111985.0A HK12111985A HK1171261A1 HK 1171261 A1 HK1171261 A1 HK 1171261A1 HK 12111985 A HK12111985 A HK 12111985A HK 1171261 A1 HK1171261 A1 HK 1171261A1
Authority
HK
Hong Kong
Prior art keywords
renal
prognosis
diagnosis
compositions
methods
Prior art date
Application number
HK12111985.0A
Other languages
English (en)
Chinese (zh)
Inventor
.安德貝里
.格雷
.麥克弗森
.中村
.坎普夫
Original Assignee
阿斯圖特醫藥公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 阿斯圖特醫藥公司 filed Critical 阿斯圖特醫藥公司
Publication of HK1171261A1 publication Critical patent/HK1171261A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96402Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
    • G01N2333/96405Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
    • G01N2333/96408Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
    • G01N2333/96413Cysteine endopeptidases (3.4.22)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK12111985.0A 2009-11-07 2012-11-22 Methods and compositions for diagnosis and prognosis of renal injury and renal failure HK1171261A1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US25914109P 2009-11-07 2009-11-07
US25916309P 2009-11-07 2009-11-07
US25914309P 2009-11-07 2009-11-07
US25914209P 2009-11-07 2009-11-07
US25914009P 2009-11-07 2009-11-07
US25951109P 2009-11-09 2009-11-09
US25954009P 2009-11-09 2009-11-09
PCT/US2010/055730 WO2011057147A1 (en) 2009-11-07 2010-11-05 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Publications (1)

Publication Number Publication Date
HK1171261A1 true HK1171261A1 (en) 2013-03-22

Family

ID=43970379

Family Applications (2)

Application Number Title Priority Date Filing Date
HK12111985.0A HK1171261A1 (en) 2009-11-07 2012-11-22 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK15111802.8A HK1211084A1 (en) 2009-11-07 2015-12-01 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15111802.8A HK1211084A1 (en) 2009-11-07 2015-12-01 Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Country Status (11)

Country Link
US (1) US10324093B2 (de)
EP (1) EP2496942B1 (de)
JP (2) JP2013510322A (de)
CN (2) CN102725635B (de)
AU (1) AU2010315008B2 (de)
CA (1) CA2779902A1 (de)
EA (1) EA201290192A1 (de)
HK (2) HK1171261A1 (de)
MX (1) MX340078B (de)
NZ (2) NZ599773A (de)
WO (1) WO2011057147A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3761034A3 (de) * 2011-01-26 2021-02-17 University of Pittsburgh - Of the Commonwealth System of Higher Education Urinbiomarker zur vorhersage der erholung nach einer akuten nierenverletzung: proteomik
AU2012282917A1 (en) * 2011-07-09 2014-01-30 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2766734A1 (de) * 2011-10-14 2014-08-20 Pronota NV Procathepsin-l und cathepsin-l als biomarker für ischämie
AR094118A1 (es) * 2012-12-20 2015-07-08 Novartis Ag Lesion renal aguda
EP2990800A1 (de) 2014-08-29 2016-03-02 Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol Neprilysin als prognostischer Marker für Herzinsuffizienz
EP3968022A1 (de) * 2014-10-20 2022-03-16 Astute Medical, Inc. Verfahren und zusammensetzungen zur diagnose und prognose von nierenläsion und niereninsuffizienz
WO2016201349A1 (en) * 2015-06-11 2016-12-15 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP7122009B2 (ja) * 2017-06-14 2022-08-19 コデクシス, インコーポレイテッド 産業上の生体触媒作用のための操作されたトランスアミナーゼポリペプチド
CN109557309B (zh) * 2018-12-04 2021-09-10 九江学院附属医院 碳酸酐酶-2作为检测标记物在肾结石诊断方面的应用

Family Cites Families (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1429031A1 (ru) 1986-06-20 1988-10-07 Калининский Государственный Медицинский Институт Способ дифференциальной диагностики гломерулонефрита и пиелонефрита
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5939272A (en) 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
JPH05504841A (ja) 1990-09-14 1993-07-22 バイオサイト・ダイアグノスティックス・インコーポレイテッド リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途
US5955377A (en) 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
EP0585310B1 (de) 1991-04-10 1999-03-17 Biosite Diagnostics Inc. "crosstalk"- oder übersprech-inhibitoren und ihre verwendung
JP3290988B2 (ja) 1991-04-11 2002-06-10 バイオサイト・ダイアグノスティックス・インコーポレイテッド 多重リガンドを同時検出する新規接合体及び検定法
US5885527A (en) 1992-05-21 1999-03-23 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membrances
US6143576A (en) 1992-05-21 2000-11-07 Biosite Diagnostics, Inc. Non-porous diagnostic devices for the controlled movement of reagents
US5494829A (en) 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5824799A (en) 1993-09-24 1998-10-20 Biosite Diagnostics Incorporated Hybrid phthalocyanine derivatives and their uses
US6498142B1 (en) 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
CA2257851C (en) 1996-05-24 2011-11-15 Biogen, Inc. Modulators of tissue regeneration
US5753455A (en) 1996-09-03 1998-05-19 Bayer Corporation Method for the detection of lysozyme using a protein error indicator dye in conjunction with an alkane sulfonic acid
US6113855A (en) 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US5947124A (en) 1997-03-11 1999-09-07 Biosite Diagnostics Incorporated Diagnostic for determining the time of a heart attack
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
EP0984984A2 (de) 1997-06-03 2000-03-15 Sagami Chemical Research Center Menschliche proteine mit transmembrandomänen und dns, die für diese kodieren
US20060223077A1 (en) 1997-06-06 2006-10-05 Human Genome Sciences, Inc. 207 human secreted proteins
US6218122B1 (en) 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
US6958147B1 (en) 1998-10-26 2005-10-25 Licentia Ltd Use of VEGF-C to prevent restenosis
ATE376187T1 (de) 1998-12-21 2007-11-15 Univ Monash Nachweis von erkrankungen der nieren und behandlung
RU2180965C1 (ru) 2000-07-03 2002-03-27 Габбасова Наталья Вадимовна Способ дифференциальной диагностики заболеваний почек
EP1405072A2 (de) 2000-12-29 2004-04-07 Oxford GlycoSciences (UK) Limited Proteine, gene und ihre verwendungen zur diagnose und behandlung von nierenkrankheiten
US20060088823A1 (en) 2001-03-29 2006-04-27 Brian Haab Microarray gene expression profiling in clear cell renal cell carcinoma : prognosis and drug target identification
US20070015146A1 (en) 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
US7235358B2 (en) 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20030003588A1 (en) 2001-06-28 2003-01-02 Comper Wayne D. Method for kidney disease detection by protein profiling
JP2006508014A (ja) 2001-07-24 2006-03-09 イエール・ユニバーシテイ キチナーゼおよびキチナーゼ様分子、ならびに炎症性疾患に関する方法、組成物およびキット
US6784154B2 (en) 2001-11-01 2004-08-31 University Of Utah Research Foundation Method of use of erythropoietin to treat ischemic acute renal failure
US8404229B2 (en) 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
GB0130557D0 (en) 2001-12-20 2002-02-06 Serono Internat S A Proteins
AU2003219275B2 (en) 2002-03-07 2008-01-24 Cambridge Enterprise Ltd SCD fingerprints
EP1532268A4 (de) 2002-03-21 2006-07-05 Yissum Res Dev Co Zur diagnose von multipler sklerose geeignete periphere blutzellenmarker sowie diese nutzende verfahren und kits
US7138230B2 (en) 2002-12-06 2006-11-21 Renovar, Inc. Systems and methods for characterizing kidney diseases
US7138229B2 (en) 2002-12-06 2006-11-21 Renovar, Inc. Systems and methods for characterizing kidney diseases
WO2004005934A2 (en) 2002-07-04 2004-01-15 Oxford Glycosciences (Uk) Ltd Toxicity markers
US6941172B2 (en) 2002-11-18 2005-09-06 Zvi Nachum Method and device for restoring kidney function using electromagnetic stimulation
US20060063156A1 (en) 2002-12-06 2006-03-23 Willman Cheryl L Outcome prediction and risk classification in childhood leukemia
CN1791797A (zh) 2003-03-27 2006-06-21 儿童医院医疗中心 用于检测肾小管细胞损伤的早发的方法和试剂盒
AU2004229501B2 (en) 2003-04-11 2011-08-18 Medimmune, Llc Recombinant IL-9 antibodies and uses thereof
WO2005002416A2 (en) 2003-06-04 2005-01-13 Joslin Diabetes Center, Inc. Predictors of renal disease
US20050148029A1 (en) 2003-09-29 2005-07-07 Biosite, Inc. Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes
GB0329288D0 (en) 2003-12-18 2004-01-21 Inverness Medical Switzerland Monitoring method and apparatus
US20070280930A1 (en) 2004-03-17 2007-12-06 Kasper Mathias Antoon Rouschop Cd44-Targeting for Reducing/Preventing Ischemia-Reperfusion-Injury
BRPI0510266A (pt) 2004-04-26 2007-10-30 Childrens Medical Center métodos para a detecção de uma doença ou distúrbio angiogênico em um indivìduo, para a detecção de cáncer em um indivìduo, para o tratamento de um indivìduo afetado com uma doença ou distúrbio angiogênico, para a determinação da probabilidade de eficácia de uma terapia anti-angiogênica, para a determinação da eficácia de uma terapia de teste na modulação dos nìveis de reguladores angiogênicos de plaqueta, para a criação de um registro ou perfil de plaqueta para uma doença ou distúrbio angiogênico e para a monitoração da eficácia de uma terapia em um indivìduo com uma doença ou distúrbio angiogênico
US20050272101A1 (en) 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
US7588892B2 (en) 2004-07-19 2009-09-15 Entelos, Inc. Reagent sets and gene signatures for renal tubule injury
US20080038192A1 (en) 2004-07-19 2008-02-14 Neurochem Inc. Diagnostic Methods Of Multiple Organ Amyloidosis
US7141382B1 (en) 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
AU2006210837B2 (en) 2005-01-31 2012-07-12 Genentech, Inc. Anti-EphB2 antibodies and methods using same
WO2006083986A2 (en) * 2005-02-01 2006-08-10 Government Of The U.S.A, As Represented By The Secretary Department Of Health & Human Services Biomarkers for tissue status
US20060205625A1 (en) 2005-02-18 2006-09-14 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and diuretics
JP2008537875A (ja) 2005-03-14 2008-10-02 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 固形臓器移植レシピエントにおいて移植片生着を評価するための方法および組成物
US7608413B1 (en) 2005-03-25 2009-10-27 Celera Corporation Kidney disease targets and uses thereof
US20070037232A1 (en) 2005-03-31 2007-02-15 Barasch Jonathan M Detection of NGAL in chronic renal disease
EP1877559B1 (de) 2005-04-18 2010-10-13 Mitomics Inc. Mitochondriale mutationen und umlagerungen als diagnostisches werkzeug zum nachweis von sonneneinstrahlung, prostatakrebs und anderen krebserkrankungen
US20070087387A1 (en) 2005-04-21 2007-04-19 Prasad Devarajan Method for the Early Detection of Renal Disease Using Proteomics
WO2007013919A2 (en) 2005-07-21 2007-02-01 The Johns Hopkins University Methods of detecting and treating acute kidney injury
US7759077B2 (en) 2005-08-02 2010-07-20 Shariat Shahrokh F Soluble fas urinary marker for the detection of bladder transitional cell carcinoma
EP1757940A1 (de) 2005-08-26 2007-02-28 Cézanne S.A.S. In vitro Methode zur Diagnose und zum Monitoring von Nierenzellkarzinom unter Verwendung von MMP-7 als humoraler Biomarker für Nierenzellkarzinom
JP2009510478A (ja) 2005-10-03 2009-03-12 バイオサイト インコーポレイテッド 全身性炎症反応症候群の診断および/または予後診断のための方法および組成物
US20080090304A1 (en) 2006-10-13 2008-04-17 Barasch Jonathan Matthew Diagnosis and monitoring of chronic renal disease using ngal
US8329408B2 (en) 2005-10-31 2012-12-11 Bayer Healthcare Llc Methods for prognosis and monitoring cancer therapy
US10716749B2 (en) 2005-11-03 2020-07-21 Palo Alto Investors Methods and compositions for treating a renal disease condition in a subject
WO2007054975A1 (en) 2005-11-08 2007-05-18 Panacea Biotec Ltd Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders
US20080133141A1 (en) 2005-12-22 2008-06-05 Frost Stephen J Weighted Scoring Methods and Use Thereof in Screening
TW200726845A (en) 2006-01-02 2007-07-16 Nat Defense Medical Ct Biomarker molecular of renal illness and detecting method for the same
GB0605217D0 (en) 2006-03-15 2006-04-26 Novartis Ag Method and compositions for assessing acute rejection
GB0606776D0 (en) 2006-04-03 2006-05-10 Novartis Pharma Ag Predictive biomarkers for chronic allograft nephropathy
US7662578B2 (en) * 2006-04-21 2010-02-16 Children's Hospital Medical Center Method and kit for the early detection of impaired renal status
US20070278989A1 (en) 2006-05-17 2007-12-06 Jay Leboff Power supply with solar charged battery
US20080038269A1 (en) 2006-05-25 2008-02-14 Mount Sinai Hospital Methods for detecting and treating kidney disease
WO2008084331A2 (en) 2006-06-21 2008-07-17 Hopitaux Universitaires De Geneve Biomarkers for renal disorders
WO2008005375A2 (en) 2006-06-30 2008-01-10 Merck & Co., Inc. Kidney toxicity biomarkers
EP2049713A4 (de) 2006-07-21 2010-06-16 Univ Alberta Gewebeabstossung
GB0617429D0 (en) 2006-09-05 2006-10-18 Electrophoretics Ltd Markers of renal transplant rejection and renal damage
US20080206794A1 (en) 2006-09-15 2008-08-28 Renovar Incorporated Systems And Methods For Characterizing Contrast Induced-Nephropathy
US7842472B2 (en) 2006-11-14 2010-11-30 Alere International Methods and compositions for monitoring and risk prediction in cardiorenal syndrome
WO2008073899A2 (en) 2006-12-08 2008-06-19 The Children's Hospital Of Philadelphia Prrg4-associated compositions and methods of use thereof in methods of tumor diagnosis
GB0701626D0 (en) 2007-01-22 2007-03-07 Cambridge Entpr Ltd Methods and biomarkers for diagnosing and monitoring psychotic disorders
WO2008104803A2 (en) 2007-02-26 2008-09-04 Oxford Genome Sciences (Uk) Limited Proteins
US8221995B2 (en) 2007-03-23 2012-07-17 Seok-Won Lee Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
EP2479568B1 (de) 2007-03-26 2015-01-07 Novartis AG Prognostische Biomarker der renalen Sicherheit und Biomarker-Signatur zur Überwachung der Nierenfunktion
CA2682538A1 (en) 2007-04-10 2008-10-16 Integragen Human diabetes susceptibility tnfrsf10b gene
US8080394B2 (en) 2007-04-27 2011-12-20 Brigham And Women's Hospital Method for determining predisposition to pulmonary infection
WO2008150488A1 (en) 2007-06-01 2008-12-11 Laboratory Corporation Of America Holdings Methods and systems for quantification of peptides and other analytes
US20100184110A1 (en) * 2007-06-06 2010-07-22 Siemens Healthcare Diagnostics Inc. Predictive diagnostics for kidney disease
US20090047689A1 (en) 2007-06-20 2009-02-19 John Kolman Autoantigen biomarkers for early diagnosis of lung adenocarcinoma
US20100267041A1 (en) 2007-09-14 2010-10-21 Predictive Biosciences, Inc. Serial analysis of biomarkers for disease diagnosis
WO2009038742A2 (en) 2007-09-20 2009-03-26 Caritas St. Elizabeth's Medical Center Of Boston, Inc. Method for estimating risk of acute kidney injury
US8039227B2 (en) 2007-09-20 2011-10-18 University Of Louisville Research Foundation, Inc. Peptide biomarkers predictive of renal function decline and kidney disease
US8003333B2 (en) 2007-09-28 2011-08-23 Mayo Foundation For Medical Education And Research Serum biomarkers for early detection of acute cellular rejection
CA2716854A1 (en) 2008-02-29 2009-09-03 National University Corporation Nagoya University Biomarker for the estimation of acute renal disorder and prognosis of the disorder, and use of the biomarker
US20090298106A1 (en) 2008-05-30 2009-12-03 Therapeutic Monitoring Services, L.L.C. Methods for Monitoring Immunosuppressant Drug Levels, Renal Function, and Hepatic Function Using Small Volume Samples
US8241861B1 (en) 2008-07-08 2012-08-14 Insilicos, Llc Methods and compositions for diagnosis or prognosis of cardiovascular disease
EP2149613A1 (de) 2008-07-28 2010-02-03 Greenwood Genetic Center, Inc. Verfahren zur Bestimmung der Dysregulierung der Methylation von hirnexprimierten Genen auf dem X-Chromosom zur Diagnose von autistischen Spektrumsstörungen
US8673574B2 (en) 2008-08-21 2014-03-18 Pxbiosciences Llc Diagnosis and monitoring of renal failure using peptide biomarkers
MX341926B (es) 2008-08-28 2016-09-07 Astute Medical Inc Metodos y composiciones para la diagnosis y prognosis de daño renal y falla renal.
EP2813848A3 (de) 2008-08-29 2015-03-11 Astute Medical, Inc. Verfahren und Zusammensetzungen zur Diagnose und Prognose von Nierenläsion und Niereninsuffizienz
US8501489B2 (en) 2008-09-26 2013-08-06 University of Pittsburgh—of the Commonwealth System of Higher Education Urinary biomarkers to predict long-term dialysis
NZ592358A (en) 2008-10-21 2013-05-31 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure using tissue inhibitor of metalloproteinase 2 (timp-2)
WO2010048347A2 (en) 2008-10-21 2010-04-29 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
KR20110084286A (ko) 2008-11-10 2011-07-21 아스튜트 메디컬 인코포레이티드 신손상 및 신부전의 진단 및 예후 예측을 위한 방법 및 조성물
NZ601575A (en) 2009-02-06 2014-08-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and failure
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010111746A1 (en) 2009-04-03 2010-10-07 Vegenics Limited Anti-vegf-d antibodies
EP2427494B1 (de) 2009-05-08 2017-10-18 Novartis AG Methoden zur modulation von fibrose mittels bmp-9 modulatoren
CA2770266A1 (en) 2009-08-07 2011-02-10 Rules-Based Medicine, Inc. Methods and devices for detecting kidney damage
AU2010295287B2 (en) 2009-09-21 2014-09-04 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2784889C (en) 2009-12-20 2018-06-19 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US20130035290A1 (en) 2011-05-17 2013-02-07 Yale University Chitinase-3-Like Protein 1 as a Biomarker of Recovery from Kidney Injury

Also Published As

Publication number Publication date
CN102725635B (zh) 2015-05-20
NZ599773A (en) 2014-09-26
MX340078B (es) 2016-06-24
WO2011057147A1 (en) 2011-05-12
JP6185035B2 (ja) 2017-08-23
US20120231476A1 (en) 2012-09-13
CN102725635A (zh) 2012-10-10
HK1211084A1 (en) 2016-05-13
EP2496942A1 (de) 2012-09-12
AU2010315008B2 (en) 2015-12-03
CN104793000A (zh) 2015-07-22
NZ628085A (en) 2015-12-24
EP2496942A4 (de) 2013-06-19
MX2012005218A (es) 2012-08-03
CA2779902A1 (en) 2011-05-12
EA201290192A1 (ru) 2013-02-28
AU2010315008A1 (en) 2012-05-31
EP2496942B1 (de) 2017-03-22
US10324093B2 (en) 2019-06-18
JP2013510322A (ja) 2013-03-21
JP2016029379A (ja) 2016-03-03

Similar Documents

Publication Publication Date Title
HK1211082A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1212776A1 (zh) 用於診斷和預後腎損傷和腎衰竭的方法和組合物
HK1213320A1 (zh) 用於診斷和預後腎損傷和腎衰竭的方法和組合物
EP2480882A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1203619A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1208074A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1199929A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1199931A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1167455A1 (zh) 用於腎損傷和腎衰竭的診斷及預後方法和組合物
HK1159755A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2539712A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1214864A1 (zh) 用於腎損傷和腎衰竭的診斷及預後的方法和組合物
EP2531620A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1200218A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1167888A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1211084A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1212774A1 (zh) 用於腎損傷和腎衰竭的診斷及預後方法和組合物
EP2462446A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2531622A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2585825A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2531621A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
EP2593794A4 (de) Verfahren und zusammensetzungen zur diagnose und prognose von nierenverletzungen und niereninsuffizienz
HK1197298A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20191030