HK1152317A1 - Synthetic scfv analogue to the 6313/g2 (anti angiotensin ii type 1 receptor) monoclonal antibody variable regions - Google Patents

Synthetic scfv analogue to the 6313/g2 (anti angiotensin ii type 1 receptor) monoclonal antibody variable regions

Info

Publication number
HK1152317A1
HK1152317A1 HK11106436.6A HK11106436A HK1152317A1 HK 1152317 A1 HK1152317 A1 HK 1152317A1 HK 11106436 A HK11106436 A HK 11106436A HK 1152317 A1 HK1152317 A1 HK 1152317A1
Authority
HK
Hong Kong
Prior art keywords
receptor
type
monoclonal antibody
variable regions
antibody variable
Prior art date
Application number
HK11106436.6A
Other languages
English (en)
Inventor
Gavin Paul Vinson
Stewart Baker
John Richard Puddefoot
Original Assignee
Queen Mary & Westfield College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Queen Mary & Westfield College filed Critical Queen Mary & Westfield College
Publication of HK1152317A1 publication Critical patent/HK1152317A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK11106436.6A 2008-02-18 2011-06-22 Synthetic scfv analogue to the 6313/g2 (anti angiotensin ii type 1 receptor) monoclonal antibody variable regions HK1152317A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0802931.6A GB0802931D0 (en) 2008-02-18 2008-02-18 Synthetic scFv analogue to the 6313/G2 (anti angiotensin II type 1 receptor) monoclonal anitbody variable regions
PCT/GB2009/000443 WO2009103969A1 (en) 2008-02-18 2009-02-18 Synthetic scfv analogue to the 6313/g2 (anti angiotensin ii type 1 receptor) monoclonal antibody variable regions

Publications (1)

Publication Number Publication Date
HK1152317A1 true HK1152317A1 (en) 2012-02-24

Family

ID=39271866

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11106436.6A HK1152317A1 (en) 2008-02-18 2011-06-22 Synthetic scfv analogue to the 6313/g2 (anti angiotensin ii type 1 receptor) monoclonal antibody variable regions

Country Status (16)

Country Link
US (2) US8487082B2 (ko)
EP (1) EP2262833B1 (ko)
JP (2) JP2011512348A (ko)
KR (1) KR101637614B1 (ko)
CN (1) CN101990548B (ko)
AU (2) AU2009216535B2 (ko)
BR (1) BRPI0905964A2 (ko)
CA (1) CA2715632A1 (ko)
ES (1) ES2404081T3 (ko)
GB (1) GB0802931D0 (ko)
HK (1) HK1152317A1 (ko)
IL (1) IL207658A (ko)
PL (1) PL2262833T3 (ko)
PT (1) PT2262833E (ko)
RU (1) RU2512071C2 (ko)
WO (1) WO2009103969A1 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2777527C (en) 2009-12-23 2020-06-23 Esbatech, An Alcon Biomedical Research Unit Llc Method for decreasing immunogenicity
CA2830503A1 (en) * 2011-03-17 2012-09-20 Minerva Biotechnologies Corporation Method for making pluripotent stem cells
EA039745B1 (ru) * 2014-03-12 2022-03-05 Нейриммьюн Холдинг Аг Новые соединения, способные противодействовать повреждению -клеток, индуцируемому островковым амилоидным полипептидом, и нарушению толерантности к глюкозе
EP3908603A4 (en) * 2019-01-11 2023-01-11 Minerva Biotechnologies Corporation ANTI-VARIABLE MUC1* ANTIBODIES AND USES THEREOF
CN112807281A (zh) * 2019-10-31 2021-05-18 南京海维医药科技有限公司 包含血管紧张素ii的稳定组合物及其制备方法、使用方法
WO2021142253A1 (en) * 2020-01-10 2021-07-15 President And Fellows Of Harvard College Anti-angiotensin ii type 1 receptor (agtr1) binding proteins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427922A (en) 1992-04-07 1995-06-27 Takeda Chemical Industries, Ltd. DNA encoding a new angiotensin II type 1 receptor subtype and its expression
GB9319877D0 (en) 1993-09-27 1993-11-10 Queen Mary Novel hybridoma & monoclonal antibodies produced thereby
TW448185B (en) 1993-11-05 2001-08-01 Lilly Co Eli Vaccine design and production
US6280994B1 (en) 1998-11-25 2001-08-28 Zymogenetics, Inc. Zace 1: a human metalloenzyme
CZ293257B6 (cs) * 1998-12-23 2004-03-17 Novartis Ag Farmaceutický přípravek obsahující antagonistu receptoru AT1 pro léčení nemocí spojených s nárůstem receptorů AT1 v subepiteliální vrstvě
US6641811B1 (en) * 2000-02-10 2003-11-04 Cornell Research Foundation, Inc. Use of angiotensin II inhibitors to prevent malignancies associated with immunosuppression
WO2002061087A2 (en) 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
GB0219524D0 (en) * 2002-08-21 2002-10-02 Queen Mary & Westfield College Therapeutic uses of monoclonal antibodies to the angiotensin-II type-1 receptor

Also Published As

Publication number Publication date
RU2010135976A (ru) 2012-03-27
AU2009216535A1 (en) 2009-08-27
US9422369B2 (en) 2016-08-23
AU2009216535B2 (en) 2014-10-23
JP2015110580A (ja) 2015-06-18
JP5997245B2 (ja) 2016-09-28
RU2512071C2 (ru) 2014-04-10
EP2262833B1 (en) 2013-02-13
BRPI0905964A2 (pt) 2015-08-18
PL2262833T3 (pl) 2013-07-31
ES2404081T3 (es) 2013-05-23
EP2262833A1 (en) 2010-12-22
CA2715632A1 (en) 2009-08-27
JP2011512348A (ja) 2011-04-21
CN101990548A (zh) 2011-03-23
WO2009103969A8 (en) 2010-01-14
IL207658A (en) 2014-12-31
WO2009103969A4 (en) 2009-10-15
CN101990548B (zh) 2014-09-17
US20110081350A1 (en) 2011-04-07
WO2009103969A1 (en) 2009-08-27
GB0802931D0 (en) 2008-03-26
IL207658A0 (en) 2010-12-30
US20140127205A1 (en) 2014-05-08
US8487082B2 (en) 2013-07-16
AU2014213549A1 (en) 2016-03-03
PT2262833E (pt) 2013-04-08
KR101637614B1 (ko) 2016-07-08
KR20100118596A (ko) 2010-11-05

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Legal Events

Date Code Title Description
AM Amended specification (according sect 146 of patent law)

Free format text: ADDITION OF INVENTOR: CORRECTION OF THE NAME OF APPLICANT FROM QUEEN MARY AND WESTFIELD - COLLEGE TO QUEEN MARY AND WESTFIELD COLLEGE, UNIVERSITY OF - LONDON

Effective date: 20130515

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180218