HK1141559A1 - 核糖核苷酸標記核酸檢測 - Google Patents
核糖核苷酸標記核酸檢測Info
- Publication number
- HK1141559A1 HK1141559A1 HK10107755.8A HK10107755A HK1141559A1 HK 1141559 A1 HK1141559 A1 HK 1141559A1 HK 10107755 A HK10107755 A HK 10107755A HK 1141559 A1 HK1141559 A1 HK 1141559A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- ribonucleotide
- nucleic acid
- acid detection
- tag nucleic
- tag
- Prior art date
Links
- 108091028664 Ribonucleotide Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 239000002336 ribonucleotide Substances 0.000 title 1
- 125000002652 ribonucleotide group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4672008P | 2008-04-21 | 2008-04-21 | |
| US12/421,188 US10150990B2 (en) | 2008-04-21 | 2009-04-09 | Ribonucleotide tag nucleic acid detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1141559A1 true HK1141559A1 (zh) | 2010-11-12 |
Family
ID=40810047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK10107755.8A HK1141559A1 (zh) | 2008-04-21 | 2010-08-13 | 核糖核苷酸標記核酸檢測 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10150990B2 (zh) |
| EP (1) | EP2112230B1 (zh) |
| JP (1) | JP5483403B2 (zh) |
| CN (1) | CN101649354B (zh) |
| CA (1) | CA2663302C (zh) |
| ES (1) | ES2392783T3 (zh) |
| HK (1) | HK1141559A1 (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2180065A1 (en) * | 2008-10-24 | 2010-04-28 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Method of reducing the molecular weight of at least one PCR product for its detection while maintaining its identity |
| GB2521570B (en) * | 2012-09-24 | 2021-01-06 | Irepertoire Inc | Multiplex pyrosequencing using non-interfering noise cancelling polynucleotide identification tags |
| US9828629B2 (en) | 2013-03-15 | 2017-11-28 | Roche Molecular Systems, Inc. | Nucleic acid target identification by structure based probe cleavage |
| US10106842B2 (en) | 2013-03-15 | 2018-10-23 | Roche Molecular Systems, Inc. | Nucleic acid target identification by structure based probe cleavage |
| US9637791B2 (en) | 2013-12-20 | 2017-05-02 | Roche Molecular Systems, Inc. | Multiplexed nucleic acid target identification by strucutre based probe cleavage |
| CN106687597B (zh) * | 2014-09-17 | 2021-02-12 | 豪夫迈·罗氏有限公司 | 通过基于结构的探针切割鉴定核酸靶标 |
| KR102468174B1 (ko) | 2016-09-15 | 2022-11-17 | 에프. 호프만-라 로슈 아게 | 멀티플렉스 pcr 수행 방법 |
| WO2023212662A2 (en) * | 2022-04-28 | 2023-11-02 | Oregon Health & Science University | Compositions and methods for modulating antigen binding activity |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| DE3529478A1 (de) | 1985-08-16 | 1987-02-19 | Boehringer Mannheim Gmbh | 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung |
| US5618711A (en) | 1986-08-22 | 1997-04-08 | Hoffmann-La Roche Inc. | Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase |
| US5374553A (en) | 1986-08-22 | 1994-12-20 | Hoffmann-La Roche Inc. | DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima |
| US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
| US5466591A (en) | 1986-08-22 | 1995-11-14 | Hoffmann-La Roche Inc. | 5' to 3' exonuclease mutations of thermostable DNA polymerases |
| US5795762A (en) | 1986-08-22 | 1998-08-18 | Roche Molecular Systems, Inc. | 5' to 3' exonuclease mutations of thermostable DNA polymerases |
| US5455170A (en) | 1986-08-22 | 1995-10-03 | Hoffmann-La Roche Inc. | Mutated thermostable nucleic acid polymerase enzyme from Thermus species Z05 |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| ES2134198T3 (es) | 1990-09-28 | 1999-10-01 | Hoffmann La Roche | Mutaciones en la 5' a 3' exonucleasa de las adn polimerasas. |
| US5484908A (en) | 1991-11-26 | 1996-01-16 | Gilead Sciences, Inc. | Oligonucleotides containing 5-propynyl pyrimidines |
| JP3739785B2 (ja) | 1991-11-26 | 2006-01-25 | アイシス ファーマシューティカルズ，インコーポレイティド | 修飾されたピリミジンを含有するオリゴマーを使用する増強された三重らせんおよび二重らせんの成形 |
| TW393513B (en) | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| CZ293215B6 (cs) | 1996-08-06 | 2004-03-17 | F. Hoffmann-La Roche Ag | Rekombinantní tepelně stálá DNA polymeráza, způsob její přípravy a prostředek, který ji obsahuje |
| CA2366231C (en) | 1999-03-18 | 2010-05-11 | Exiqon A/S | One step sample preparation and detection of nucleic acids in complex biological samples |
| US6734291B2 (en) | 1999-03-24 | 2004-05-11 | Exiqon A/S | Synthesis of [2.2.1]bicyclo nucleosides |
| DK1163250T3 (da) | 1999-03-24 | 2006-11-13 | Exiqon As | Forbedret syntese af [2.2.1]bicyclonukleosider |
| EP1173622B1 (en) | 1999-04-30 | 2005-06-15 | Methexis Genomics N.V. | Diagnostic sequencing by a combination of specific cleavage and mass spectrometry |
| US20040241651A1 (en) * | 2000-04-07 | 2004-12-02 | Alexander Olek | Detection of single nucleotide polymorphisms (snp's) and cytosine-methylations |
| US7179590B2 (en) | 2000-04-18 | 2007-02-20 | Roche Molecular Systems, Inc | High temperature reverse transcription using mutant DNA polymerases |
| US7148049B2 (en) | 2002-04-02 | 2006-12-12 | Roche Molecular Systems, Inc. | Thermostable or thermoactive DNA polymerase molecules with attenuated 3′-5′ exonuclease activity |
| CN1197976C (zh) | 2003-01-31 | 2005-04-20 | 中国人民解放军南京军区联勤部军事医学研究所 | 基因多态性检测方法 |
| EP1493824A1 (en) | 2003-07-02 | 2005-01-05 | Consortium National de Recherche en Genomique (CNRG) | Method for detection of mutations in DNA |
| US7928207B2 (en) | 2004-06-28 | 2011-04-19 | Roche Molecular Systems, Inc | Synthesis and compositions of nucleic acids comprising 2′-terminator nucleotides |
| US7745125B2 (en) | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| US7890268B2 (en) * | 2004-12-28 | 2011-02-15 | Roche Molecular Systems, Inc. | De-novo sequencing of nucleic acids |
| WO2007024800A2 (en) * | 2005-08-22 | 2007-03-01 | Applera Corporation | Device and method for making discrete volumes of a first fluid in contact with a second fluid, which are immiscible with each other |
| US8673567B2 (en) * | 2006-03-08 | 2014-03-18 | Atila Biosystems, Inc. | Method and kit for nucleic acid sequence detection |
| US8962293B2 (en) | 2006-10-18 | 2015-02-24 | Roche Molecular Systems, Inc. | DNA polymerases and related methods |
| US8026091B2 (en) | 2007-07-13 | 2011-09-27 | Roche Molecular Systems, Inc. | DNA polymerases and related methods |
-
2009
- 2009-04-09 US US12/421,188 patent/US10150990B2/en active Active
- 2009-04-17 ES ES09005451T patent/ES2392783T3/es active Active
- 2009-04-17 EP EP09005451A patent/EP2112230B1/en active Active
- 2009-04-20 JP JP2009101953A patent/JP5483403B2/ja active Active
- 2009-04-20 CN CN200910203986.1A patent/CN101649354B/zh active Active
- 2009-04-20 CA CA2663302A patent/CA2663302C/en active Active
-
2010
- 2010-08-13 HK HK10107755.8A patent/HK1141559A1/zh not_active IP Right Cessation
-
2012
- 2012-12-19 US US13/720,881 patent/US20130096027A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2112230A3 (en) | 2009-12-30 |
| US20130096027A1 (en) | 2013-04-18 |
| CA2663302C (en) | 2014-09-09 |
| ES2392783T3 (es) | 2012-12-13 |
| CA2663302A1 (en) | 2009-10-21 |
| JP2009261392A (ja) | 2009-11-12 |
| EP2112230B1 (en) | 2012-08-22 |
| US10150990B2 (en) | 2018-12-11 |
| JP5483403B2 (ja) | 2014-05-07 |
| EP2112230A2 (en) | 2009-10-28 |
| CN101649354B (zh) | 2015-04-29 |
| CN101649354A (zh) | 2010-02-17 |
| US20090263813A1 (en) | 2009-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230420 |