HK1141008A1 - 嘌呤基衍生物及其作為鉀通道調節劑的用途 - Google Patents
嘌呤基衍生物及其作為鉀通道調節劑的用途Info
- Publication number
- HK1141008A1 HK1141008A1 HK10107002.9A HK10107002A HK1141008A1 HK 1141008 A1 HK1141008 A1 HK 1141008A1 HK 10107002 A HK10107002 A HK 10107002A HK 1141008 A1 HK1141008 A1 HK 1141008A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- potassium channel
- channel modulators
- purinyl derivatives
- purinyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90850307P | 2007-03-28 | 2007-03-28 | |
DKPA200700482 | 2007-03-28 | ||
PCT/EP2008/053648 WO2008116909A1 (en) | 2007-03-28 | 2008-03-27 | Purinyl derivatives and their use as potassium channel modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1141008A1 true HK1141008A1 (zh) | 2010-10-29 |
Family
ID=39473604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10107002.9A HK1141008A1 (zh) | 2007-03-28 | 2010-07-20 | 嘌呤基衍生物及其作為鉀通道調節劑的用途 |
Country Status (8)
Country | Link |
---|---|
US (4) | US20100130516A1 (zh) |
EP (5) | EP2142545A1 (zh) |
AU (1) | AU2008231695B2 (zh) |
CA (1) | CA2682019C (zh) |
HK (1) | HK1141008A1 (zh) |
IL (1) | IL200501A0 (zh) |
MX (1) | MX2009010122A (zh) |
WO (5) | WO2008116910A1 (zh) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200837064A (en) * | 2006-10-04 | 2008-09-16 | Pharmacopeia Inc | 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression |
JP2010517970A (ja) * | 2007-02-02 | 2010-05-27 | ノイロサーチ アクティーゼルスカブ | ピリジニル−ピラゾール誘導体及びカリウムチャネル調節剤としてのそれらの使用 |
CN101646669B (zh) * | 2007-03-28 | 2013-09-04 | 神经研究公司 | 嘌呤基衍生物及其作为钾通道调节剂的用途 |
WO2008116910A1 (en) * | 2007-03-28 | 2008-10-02 | Neurosearch A/S | Purinyl derivatives and their use as potassium channel modulators |
US8415358B2 (en) | 2007-09-17 | 2013-04-09 | Neurosearch A/S | Pyrazine derivatives and their use as potassium channel modulators |
US8158624B2 (en) | 2008-05-30 | 2012-04-17 | Genetech, Inc. | Purine PI3K inhibitor compounds and methods of use |
JP2012501308A (ja) * | 2008-09-02 | 2012-01-19 | ノイロサーチ アクティーゼルスカブ | ピラゾリルピリミジン誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用 |
US8268838B2 (en) | 2008-09-26 | 2012-09-18 | Neurosearch A/S | Substituted purinyl-pyrazole derivatives and their use as potassium channel modulators |
US20110237607A1 (en) * | 2008-09-26 | 2011-09-29 | Neurosearch A/S | Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators |
PE20100362A1 (es) * | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
US8685987B2 (en) | 2009-04-01 | 2014-04-01 | Ataxion, Inc. | Substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as potassium channel modulators |
US8765770B2 (en) | 2009-04-01 | 2014-07-01 | Ataxion, Inc. | Substituted [1,2,4]triazolo[1,5-a]pyrimidines and their use as potassium channel modulators |
US20120184517A1 (en) * | 2009-04-30 | 2012-07-19 | Steven Marx | Treatment of diseases with altered smooth muscle contractility |
AR079814A1 (es) | 2009-12-31 | 2012-02-22 | Otsuka Pharma Co Ltd | Compuestos heterociclicos, composiciones farmaceuticas que los contienen y sus usos |
MX2013000389A (es) | 2010-07-14 | 2013-03-08 | Hoffmann La Roche | Compuestos de purina selectivos para fosfatidilinositol 3-cinasa p110 delta, y metodods de uso. |
TW201500358A (zh) | 2010-12-16 | 2015-01-01 | Hoffmann La Roche | 三環pi3k抑制劑化合物及其使用方法 |
WO2012142029A2 (en) * | 2011-04-10 | 2012-10-18 | Florida A&M University | Serms for the treatment of estrogen receptor-mediated disorders |
CN102351716B (zh) * | 2011-08-17 | 2013-11-06 | 中国石油化工股份有限公司 | 一种降低甲酰苯胺法制备对氨基二苯胺塔设备腐蚀的方法 |
US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
EP2885290B1 (en) | 2012-06-26 | 2017-10-18 | Saniona A/S | A phenyl triazole derivative and its use for modulating the gabaa receptor complex |
EP2970177A1 (en) | 2013-03-15 | 2016-01-20 | Pfizer Inc. | Indole compounds that activate ampk |
WO2015005491A1 (ja) * | 2013-07-12 | 2015-01-15 | 国立大学法人京都大学 | 疾病の発症又は進行の一因となる異常スプライシングを抑制できる物質のスクリーニング方法 |
EP3226861A2 (en) | 2014-12-05 | 2017-10-11 | Centre National de la Recherche Scientifique (CNRS) | Compounds for treating cystic fibrosis |
SI3303330T1 (sl) | 2015-06-03 | 2019-08-30 | Bristol-Myers Squibb Company | Agonisti 4-hidroksi-3-(heteroaril)piridin-2-on apj za uporabo pri zdravljenju kardiovaskularnih motenj |
EP3341372A1 (en) * | 2015-08-25 | 2018-07-04 | Bristol-Myers Squibb Company | Tgf beta receptor antagonists |
CA3026149A1 (en) * | 2016-06-02 | 2017-12-07 | Cadent Therapeutics, Inc. | Potassium channel modulators |
EP3528816A4 (en) * | 2016-10-21 | 2020-04-08 | Nimbus Lakshmi, Inc. | TYK2 INHIBITORS AND USES THEREOF |
DK3571193T3 (da) | 2017-01-23 | 2022-01-17 | Cadent Therapeutics Inc | Potassium Channel Modulators |
CA3116339A1 (en) | 2018-10-22 | 2020-04-30 | Cadent Therapeutics, Inc. | Crystalline forms of potassium channel modulators |
CN116178374A (zh) * | 2023-01-13 | 2023-05-30 | 河北医科大学 | 小电导钙激活钾离子通道激动剂及其合成和应用 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1066147C (zh) | 1995-11-01 | 2001-05-23 | 诺瓦提斯公司 | 嘌呤衍生物及其制备方法 |
FR2741881B1 (fr) | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
DE19834044A1 (de) * | 1998-07-29 | 2000-02-03 | Bayer Ag | Neue substituierte Pyrazolderivate |
AU2583901A (en) * | 1999-12-17 | 2001-06-25 | Ariad Pharmaceuticals, Inc. | Proton pump inhibitors |
CA2394646A1 (en) | 1999-12-17 | 2001-06-21 | Ariad Pharmaceuticals, Inc. | Novel purines |
DE60031886T2 (de) | 1999-12-17 | 2007-09-06 | Ariad Pharmaceuticals, Inc., Cambridge | Purinderivate |
IL150062A0 (en) | 1999-12-17 | 2002-12-01 | Ariad Pharma Inc | Proton pump inhibitors |
ATE301123T1 (de) | 2001-06-27 | 2005-08-15 | Cyclacel Ltd | 2,6,9-substituierte purinderivate und ihre verwendung bei der behandlung proliferativer krankheiten |
US20030078232A1 (en) * | 2001-08-08 | 2003-04-24 | Elfatih Elzein | Adenosine receptor A3 agonists |
US7262176B2 (en) * | 2001-08-08 | 2007-08-28 | Cv Therapeutics, Inc. | Adenosine A3 receptor agonists |
WO2003031406A2 (en) | 2001-10-12 | 2003-04-17 | Irm Llc | Kinase inhibitor scaffolds and methods for their preparation |
US20060009642A1 (en) * | 2001-10-12 | 2006-01-12 | Irm Llc, A Delaware Limited Liability Company | Methods for the synthesis of substituted purines |
US20030229105A1 (en) * | 2002-05-21 | 2003-12-11 | Cyclacel Limited | Treatment of autoimmune disorders |
AU2003254053A1 (en) * | 2002-07-23 | 2004-02-09 | Smithkline Beecham Corporation | Pyrazolopyrimidines as protein kinase inhibitors |
US20030139427A1 (en) * | 2002-08-23 | 2003-07-24 | Osi Pharmaceuticals Inc. | Bicyclic pyrimidinyl derivatives and methods of use thereof |
AU2003265636A1 (en) * | 2002-09-06 | 2004-03-29 | Smithkline Beecham Corporation | Pyrrolo(2, 3-d)pyrimidine-4-yl and purin-6-yl urea compounds |
MXPA06001758A (es) * | 2003-08-15 | 2006-08-11 | Irm Llc | Anilino purinas sustituidas en la posicion 6 utiles como inhibidores de rtk. |
US20050165029A1 (en) * | 2004-01-13 | 2005-07-28 | Ambit Biosciences Corporation | Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases |
JPWO2005080377A1 (ja) | 2004-02-20 | 2007-10-25 | キリンホールディングス株式会社 | TGFβ阻害活性を有する化合物およびそれを含んでなる医薬組成物 |
GB0407723D0 (en) * | 2004-04-05 | 2004-05-12 | Novartis Ag | Organic compounds |
FR2876583B1 (fr) * | 2004-10-15 | 2007-04-13 | Centre Nat Rech Scient Cnrse | Utilisation de derives de purines pour la fabrication de medicaments pour le traitement de la mucoviscidose et de maladies liees a un defaut d'adressage des proteines dans les cellules |
GB0500785D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
WO2006097441A1 (en) | 2005-03-14 | 2006-09-21 | Neurosearch A/S | Potassium channel modulating agents and their medical use |
GB0505219D0 (en) * | 2005-03-14 | 2005-04-20 | Novartis Ag | Organic compounds |
US20090036475A1 (en) * | 2005-03-22 | 2009-02-05 | Neurosearch A/S | Pyrazolyl-Pyrimidines as Potassium Channel Modulating Agents and Their Medical Use |
JP2008534472A (ja) | 2005-03-22 | 2008-08-28 | ノイロサーチ アクティーゼルスカブ | カリウムチャンネル調節剤としてのピラゾリル−ピリミジン及びその医学的使用 |
EP1881991A1 (en) * | 2005-05-19 | 2008-01-30 | Cv Therapeutics, Inc. | A1 adenosine receptor agonists |
WO2007071632A2 (en) * | 2005-12-20 | 2007-06-28 | Neurosearch A/S | 2-pyridin-2-yl-quinazoline derivatives as potassium channel modulating agents for the treatment of respiratory diseases |
TW200745847A (en) * | 2005-12-23 | 2007-12-16 | Koninkl Philips Electronics Nv | Apparatus and method for dynamic cache management |
WO2008028935A2 (en) | 2006-09-07 | 2008-03-13 | Neurosearch A/S | Pyridinyl-pyrimidine derivatives useful as potassium channel modulating agents |
EP2074113A1 (en) | 2006-10-03 | 2009-07-01 | NeuroSearch A/S | Indazolyl derivatives useful as potassium channel modulating agents |
AU2008210904A1 (en) * | 2007-01-26 | 2008-08-07 | Irm Llc | Purine compounds and compositions as kinase inhibitors for the treatment of Plasmodium related diseases |
JP2010517970A (ja) * | 2007-02-02 | 2010-05-27 | ノイロサーチ アクティーゼルスカブ | ピリジニル−ピラゾール誘導体及びカリウムチャネル調節剤としてのそれらの使用 |
WO2008116910A1 (en) * | 2007-03-28 | 2008-10-02 | Neurosearch A/S | Purinyl derivatives and their use as potassium channel modulators |
CN101646669B (zh) * | 2007-03-28 | 2013-09-04 | 神经研究公司 | 嘌呤基衍生物及其作为钾通道调节剂的用途 |
EA201000614A1 (ru) * | 2007-10-17 | 2010-10-29 | Новартис Аг | Производные пурина как лиганды аденозинового рецептора а |
US20110237607A1 (en) * | 2008-09-26 | 2011-09-29 | Neurosearch A/S | Substituted purinyl-pyrazol derivatives and their use as potassium channel modulators |
US8268838B2 (en) * | 2008-09-26 | 2012-09-18 | Neurosearch A/S | Substituted purinyl-pyrazole derivatives and their use as potassium channel modulators |
PE20100362A1 (es) * | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
-
2008
- 2008-03-27 WO PCT/EP2008/053649 patent/WO2008116910A1/en active Application Filing
- 2008-03-27 EP EP08735523A patent/EP2142545A1/en not_active Withdrawn
- 2008-03-27 US US12/593,152 patent/US20100130516A1/en not_active Abandoned
- 2008-03-27 WO PCT/EP2008/053651 patent/WO2008116911A1/en active Application Filing
- 2008-03-27 WO PCT/EP2008/053657 patent/WO2008116912A2/en active Application Filing
- 2008-03-27 EP EP08718283A patent/EP2142547A1/en not_active Withdrawn
- 2008-03-27 EP EP08735528A patent/EP2144911A2/en not_active Withdrawn
- 2008-03-27 AU AU2008231695A patent/AU2008231695B2/en active Active
- 2008-03-27 US US12/593,194 patent/US8362024B2/en active Active
- 2008-03-27 CA CA2682019A patent/CA2682019C/en active Active
- 2008-03-27 WO PCT/EP2008/053659 patent/WO2008116914A1/en active Application Filing
- 2008-03-27 EP EP08718278.8A patent/EP2142546B1/en active Active
- 2008-03-27 US US12/593,218 patent/US20100152210A1/en not_active Abandoned
- 2008-03-27 WO PCT/EP2008/053648 patent/WO2008116909A1/en active Application Filing
- 2008-03-27 EP EP08718279A patent/EP2132208A1/en not_active Withdrawn
- 2008-03-27 MX MX2009010122A patent/MX2009010122A/es active IP Right Grant
-
2009
- 2009-08-20 IL IL200501A patent/IL200501A0/en unknown
-
2010
- 2010-07-20 HK HK10107002.9A patent/HK1141008A1/zh unknown
-
2012
- 2012-12-19 US US13/720,956 patent/US9340544B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2142545A1 (en) | 2010-01-13 |
MX2009010122A (es) | 2009-10-19 |
WO2008116912A2 (en) | 2008-10-02 |
US20100130516A1 (en) | 2010-05-27 |
WO2008116910A1 (en) | 2008-10-02 |
US20100152210A1 (en) | 2010-06-17 |
EP2142547A1 (en) | 2010-01-13 |
WO2008116909A1 (en) | 2008-10-02 |
WO2008116914A1 (en) | 2008-10-02 |
EP2144911A2 (en) | 2010-01-20 |
IL200501A0 (en) | 2010-04-29 |
EP2142546B1 (en) | 2017-06-07 |
EP2132208A1 (en) | 2009-12-16 |
US8362024B2 (en) | 2013-01-29 |
AU2008231695B2 (en) | 2013-03-28 |
US20130109704A1 (en) | 2013-05-02 |
EP2142546A1 (en) | 2010-01-13 |
US9340544B2 (en) | 2016-05-17 |
WO2008116912A3 (en) | 2009-02-05 |
CA2682019A1 (en) | 2008-10-02 |
AU2008231695A1 (en) | 2008-10-02 |
US20100120797A1 (en) | 2010-05-13 |
CA2682019C (en) | 2016-08-09 |
WO2008116911A1 (en) | 2008-10-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1141008A1 (zh) | 嘌呤基衍生物及其作為鉀通道調節劑的用途 | |
ZA200905796B (en) | Purinyl derivatives and their use as potassium channel modulators | |
AP2516A (en) | 2-Pyridine carboxamide derivatives as sodium channel modulators | |
ZA201000436B (en) | Novel esterases and their use | |
EP2178373A4 (en) | HETEROCYCLES AS COLD CHANNEL MODULATORS | |
GB0701426D0 (en) | Compounds and their use | |
GB0700580D0 (en) | Use | |
HK1147968A1 (zh) | 作為刺猬蛋白信號通路調節劑的聯苯基甲酰胺類化合物 | |
GB0723794D0 (en) | Potassium ion channel modulators and uses thereof | |
PT2194783T (pt) | Composições e métodos para moduladores da apoptose | |
EP2129680A4 (en) | COMBINED HAIR-ANTISENSE HAIR LOOP COMPOSITIONS AND METHODS FOR MODULATING EXPRESSION | |
IL208771A0 (en) | Iminopyridine derivatives and use thereof | |
SI2170861T1 (sl) | Derivati 4-(n-azacikloalkil) anilidov kot kalijevi kanalski modulatorji | |
EP2170874A4 (en) | NEW COMPOUNDS AND THEIR USE | |
PT2027842E (pt) | Produto absorvente | |
EP2174629A4 (en) | BUFFER | |
GB0724246D0 (en) | Noval use | |
ZA201000357B (en) | 2-Azetidinemethaneamines and 2-pyrrolidinemethaneamines as Taar-Ligands | |
EP2310369A4 (en) | BENZYL OXYANILID DERIVATIVES SUITABLE AS SODIUM CHANNEL MODULATORS | |
GB0701096D0 (en) | Use | |
GB2454741B (en) | Wristband | |
GB0711036D0 (en) | Composition and their use | |
GB0722678D0 (en) | Compounds and their use II | |
GB0725186D0 (en) | Learners mate | |
AU2007905398A0 (en) | Novel cobalamins and use thereof |