HK1137783A1 - Methods and apparatuses for electrochemical determination of factor xa inhibitors in blood samples - Google Patents

Methods and apparatuses for electrochemical determination of factor xa inhibitors in blood samples

Info

Publication number
HK1137783A1
HK1137783A1 HK10102678.3A HK10102678A HK1137783A1 HK 1137783 A1 HK1137783 A1 HK 1137783A1 HK 10102678 A HK10102678 A HK 10102678A HK 1137783 A1 HK1137783 A1 HK 1137783A1
Authority
HK
Hong Kong
Prior art keywords
inhibitors
apparatuses
factor
methods
blood samples
Prior art date
Application number
HK10102678.3A
Other languages
English (en)
Inventor
Carina Horn
Liesel Doerge
Margarete Krzysiuk
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1137783A1 publication Critical patent/HK1137783A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HK10102678.3A 2006-10-31 2010-03-15 Methods and apparatuses for electrochemical determination of factor xa inhibitors in blood samples HK1137783A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06123234A EP1918718A1 (fr) 2006-10-31 2006-10-31 Procédés et dispositifs destinés à la détermination électrochimique d'inhibiteurs du facteur Xa dans des échantillons sanguins
PCT/EP2007/009347 WO2008052718A1 (fr) 2006-10-31 2007-10-27 Procédé et dispositifs pour la détermination électrochimique d'inhibiteurs du facteur xa dans des échantillons de sang

Publications (1)

Publication Number Publication Date
HK1137783A1 true HK1137783A1 (en) 2010-08-06

Family

ID=37633621

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10102678.3A HK1137783A1 (en) 2006-10-31 2010-03-15 Methods and apparatuses for electrochemical determination of factor xa inhibitors in blood samples

Country Status (8)

Country Link
US (2) US8636894B2 (fr)
EP (2) EP1918718A1 (fr)
JP (1) JP5395669B2 (fr)
CN (1) CN101535498B (fr)
CA (1) CA2667957C (fr)
ES (1) ES2444011T3 (fr)
HK (1) HK1137783A1 (fr)
WO (1) WO2008052718A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2471945A1 (fr) 2010-12-30 2012-07-04 Siemens Healthcare Diagnostics Products GmbH Procédé de détermination d'inhibiteurs de coagulation
WO2012124800A1 (fr) * 2011-03-16 2012-09-20 学校法人 芝浦工業大学 Capteur pour analyse d'anticoagulant
EP2818871A1 (fr) * 2013-06-28 2014-12-31 Roche Diagniostics GmbH Moyens et procédés pour étalonnage universel de tests anti-facteur Xa
US10048281B2 (en) 2014-09-26 2018-08-14 Abbott Point Of Care Inc. Cartridge device with segmented fluidics for assaying coagulation in fluid samples
CN107107057B (zh) 2014-09-26 2020-12-15 雅培医护站股份有限公司 用于流体样本中的凝结测定的盒设备识别
EP3198270A1 (fr) 2014-09-26 2017-08-02 Abbott Point Of Care, Inc. Dispositif cartouche avec jonctions fluidiques pour mesures de coagulation dans des échantillons de fluide
ES2911898T3 (es) 2014-09-26 2022-05-23 Abbott Point Of Care Inc Dispositivo de cartucho de canal único para ensayos de coagulación de sangre en muestras de fluidos
CN107110875A (zh) 2014-09-26 2017-08-29 雅培医护站股份有限公司 用在凝固测定中的鞣花酸制剂
ES2881861T3 (es) 2014-09-26 2021-11-30 Abbott Point Of Care Inc Sensores para evaluar la coagulación en muestras de fluidos
EP3197602B1 (fr) 2014-09-26 2021-09-01 Abbott Point Of Care, Inc. Dispositif microfabriqué avec des capteurs de microenvironnement pour analyser la coagulation dans des échantillons fluides
CN104714036B (zh) * 2015-04-01 2016-06-01 成都协和生物技术有限责任公司 抗凝血酶iii活性测定试剂盒的制备方法
CN105203479A (zh) * 2015-09-21 2015-12-30 山东万邦赛诺康生化制药股份有限公司 用血凝仪测定肝素或低分子量肝素效价的方法
US10794896B2 (en) * 2016-01-29 2020-10-06 Sony Corporation Blood coagulation system examination module, blood coagulation system examination system, blood coagulation system examination method, and determination method of parameter for blood coagulation system examination module
AU2017344760A1 (en) * 2016-10-20 2019-05-02 Universal Biosensors Pty Ltd Non-biohazardous solutions and methods for testing analysers
US12073926B2 (en) 2020-09-21 2024-08-27 Instrumentation Laboratory Company Detecting and monitoring oral anticoagulants or intravenous direct thrombin inhibitors in a blood sample
CN115032164B (zh) * 2022-08-10 2022-12-06 山东省食品药品检验研究院 一种肝素钠中是否含有凝血因子Xa直接抑制剂的检测方法

Family Cites Families (18)

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Publication number Priority date Publication date Assignee Title
US5093237A (en) * 1988-03-03 1992-03-03 Nippon Shoji Kabushiki Kaisha Method and reagent for determining the biological activity of antithrombin iii by measuring coagulation time
DE69108896T2 (de) * 1990-11-05 1995-08-24 Baxter Diagnostics Inc Verfahren zur bestimmung der konzentration von antikoagulantien.
US5308756A (en) * 1991-11-20 1994-05-03 Baxter Diagnostics Inc. Protein S chromogenic assay
EP0738389A1 (fr) * 1992-09-04 1996-10-23 Gradipore Limited Appareil et procede de detection de la coagulation/lyse de liquides
AU689768B2 (en) * 1993-02-17 1998-04-09 Cardiovascular Diagnostics, Inc. Dry chemistry cascade immunoassay and affinity assay
US5762770A (en) * 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
SK286094B6 (sk) * 1994-04-26 2008-03-05 Aventis Pharmaceuticals Inc. Zlúčenina špecificky inhibujúca aktivitu faktora Xa, farmaceutická kompozícia s jej obsahom a jej použitie
NL1006429C2 (nl) * 1997-06-27 1998-12-29 Univ Maastricht Werkwijze voor het bepalen van het heparinegehalte.
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
WO2000077246A2 (fr) * 1999-06-14 2000-12-21 Novo Nordisk A/S COMPOSES INHIBANT L'ACTIVITE DU COMPLEXE FVIIa/TF
WO2001044493A2 (fr) 1999-12-15 2001-06-21 Pentapharm Ag Dosage hematologique et reactif
US6438498B1 (en) * 2000-02-10 2002-08-20 I-Stat Corporation System, method and computer implemented process for assaying coagulation in fluid samples
US20030146113A1 (en) * 2000-02-21 2003-08-07 Volker Unkrig Electrochemical sensor for determining blood clotting, corresponding system for measuring blood clotting and method for determining blood clotting
JP2003524184A (ja) * 2000-02-21 2003-08-12 エフ．ホフマン−ラ ロシュ アーゲー 血液凝固測定用の電気化学センサー、対応する血液凝固測定システム、および血液凝固測定方法
US7166208B2 (en) * 2004-03-03 2007-01-23 Stephen Eliot Zweig Apoenzyme reactivation electrochemical detection method and assay
US6680177B2 (en) * 2001-12-07 2004-01-20 Cardiovascular Diagnostics, Inc. Low molecular weight heparin assay, system and reagent therefor
US7579000B2 (en) * 2002-05-01 2009-08-25 Bayer Schering Pharma Ag Tissue factor targeted antibodies as anticoagulants
WO2005031303A2 (fr) * 2003-09-22 2005-04-07 University Of North Carolina At Chapel Hill Phospholipides solubles a utiliser dans des analyses du facteur de coagulation

Also Published As

Publication number Publication date
JP2010508499A (ja) 2010-03-18
CN101535498B (zh) 2012-11-14
US20140106383A1 (en) 2014-04-17
CN101535498A (zh) 2009-09-16
EP2079849A1 (fr) 2009-07-22
CA2667957C (fr) 2013-03-05
ES2444011T3 (es) 2014-02-21
EP2079849B1 (fr) 2013-11-20
US9594042B2 (en) 2017-03-14
EP1918718A1 (fr) 2008-05-07
JP5395669B2 (ja) 2014-01-22
CA2667957A1 (fr) 2008-05-08
US20090236238A1 (en) 2009-09-24
WO2008052718A1 (fr) 2008-05-08
US8636894B2 (en) 2014-01-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181031