HK1133254A1 - Compound having affinity for amyloid - Google Patents

Compound having affinity for amyloid

Info

Publication number
HK1133254A1
HK1133254A1 HK09111320.9A HK09111320A HK1133254A1 HK 1133254 A1 HK1133254 A1 HK 1133254A1 HK 09111320 A HK09111320 A HK 09111320A HK 1133254 A1 HK1133254 A1 HK 1133254A1
Authority
HK
Hong Kong
Prior art keywords
amyloid
affinity
compound
Prior art date
Application number
HK09111320.9A
Other languages
English (en)
Inventor
Shigeyuki Tanifuji
Akio Hayashi
Daisaku Nakamura
Shinya Takasaki
Anthony Eamon Storey
Denis Raymond Christophe Bouvet
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of HK1133254A1 publication Critical patent/HK1133254A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK09111320.9A 2006-06-21 2009-12-03 Compound having affinity for amyloid HK1133254A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80535606P 2006-06-21 2006-06-21
JP2006188034 2006-07-07
PCT/JP2007/062503 WO2007148755A1 (ja) 2006-06-21 2007-06-21 新規アミロイド親和性化合物

Publications (1)

Publication Number Publication Date
HK1133254A1 true HK1133254A1 (en) 2010-03-19

Family

ID=38833493

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09111320.9A HK1133254A1 (en) 2006-06-21 2009-12-03 Compound having affinity for amyloid

Country Status (10)

Country Link
US (1) US8277777B2 (de)
EP (1) EP2042501B1 (de)
KR (1) KR20090025282A (de)
CN (1) CN101501033B (de)
AU (1) AU2007261985B2 (de)
CA (1) CA2655826A1 (de)
HK (1) HK1133254A1 (de)
IL (1) IL196046A0 (de)
NO (1) NO20090233L (de)
WO (1) WO2007148755A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
ATE535527T1 (de) 2006-05-19 2011-12-15 Nihon Mediphysics Co Ltd Verbindung mit affinität zu amyloid
TW200823211A (en) 2006-11-30 2008-06-01 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
TW200918102A (en) * 2007-10-24 2009-05-01 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
CA2704027A1 (en) * 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
EP2218464A1 (de) * 2009-02-11 2010-08-18 Technische Universität München Verbindungen zur nichtinvasiven Messung von Aggregaten von Amyloidpeptiden
KR101123178B1 (ko) * 2009-04-09 2012-06-13 (주)에스메디 2-아릴벤조싸이오펜 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 퇴행성 뇌질환의 진단 또는 치료용 약학적 조성물
AU2012274639B2 (en) * 2011-06-24 2016-08-11 Nihon Medi-Physics Co., Ltd. Novel compound with amyloid affinity
KR20160003173A (ko) 2013-04-29 2016-01-08 에프. 호프만-라 로슈 아게 2-페닐 또는 2-헤트아릴 이미다졸[1,2-a]피리딘 유도체
CN103724207B (zh) * 2013-12-20 2016-07-06 北京智博高科生物技术有限公司 苯基苄基醚类衍生物及其制备方法和应用
AU2015308769A1 (en) * 2014-08-29 2017-03-23 Chdi Foundation, Inc. Probes for imaging huntingtin protein
US9926316B2 (en) * 2016-03-03 2018-03-27 The Cleveland Clinic Foundation Antitumor derivatives for differentiation therapy
CN108822105A (zh) * 2018-08-14 2018-11-16 河南师范大学 一种由乙苯类化合物合成2-芳基咪唑并[1,2-a]吡啶类化合物的方法

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US4833149A (en) 1986-09-22 1989-05-23 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo[1,2-a]pyridines
US4727145A (en) 1986-09-22 1988-02-23 Ortho Pharmaceutical Corporation 2- Or 3- aryl substituted imidazo [1,2-a]pyridines
US4871745A (en) * 1986-09-22 1989-10-03 Ortho Pharmaceutical Corporation 2- or 3-aryl substituted imidazo(1,2-A)pyridines and their use as antisecretory agents
EP0859642A2 (de) 1995-10-17 1998-08-26 G.D. Searle & Co. Verfahren zur detektion von zyklooxygenase-2
US6812327B1 (en) 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
EP1105163A4 (de) 1998-08-20 2003-05-02 Univ California Verfahren zur markierung amyloider plaques und neurofibrillisches gewirrs
JP4025468B2 (ja) 1999-07-29 2007-12-19 三井化学株式会社 有機電界発光素子
EP1268478B1 (de) 2000-03-31 2007-05-02 Ortho-McNeil Pharmaceutical, Inc. Phenyl-substituierte imidazopyridine
US20010051632A1 (en) 2000-03-31 2001-12-13 Wenying Chai Phenyl-substituted indolizines and tetrahydroindolizines
AU2001249672A1 (en) * 2000-03-31 2001-10-15 Ortho-Mcneil Pharmaceutical, Inc. Method for using 2- or 3-aryl substituted imidazo(1,2-a) pyridines as h3 antagonists
DE10040016A1 (de) 2000-08-16 2002-02-28 Boehringer Ingelheim Pharma Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US6514969B2 (en) 2000-08-16 2003-02-04 Boehringer Ingelheim Pharma Kg β-amyloid inhibitors, processes for preparing them, and their use in pharmaceutical compositions
WO2002016333A2 (en) 2000-08-24 2002-02-28 University Of Pittsburgh Thioflavin derivatives and their use in diagnosis and theraphy of alzheimer's disease
MXPA03007595A (es) 2001-02-26 2003-12-04 Bristol Myers Squibb Pharma Co Analogos de acido ascorbico para metalorradiofarmaceuticos.
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
TWI245764B (en) 2001-04-23 2005-12-21 Hank F Kung Amyloid plaque aggregation inhibitors and diagnostic imaging agents
JP4436928B2 (ja) 2001-08-27 2010-03-24 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア スチルベン誘導体、およびアミロイド斑の結合および画像化のためのその使用
GB0205281D0 (en) 2002-03-06 2002-04-17 Novartis Ag Organic compounds
EP1356827A1 (de) 2002-04-24 2003-10-29 Mallinckrodt Inc. Verfahren zur Herstellung von einer 2-18F-Fluor-2-Deoxy-D-Glucose (18F-FDG)-Lösung
AU2003242233A1 (en) 2002-06-12 2003-12-31 Bf Research Institute, Inc. Probe compound for image diagnosis of disease with amyloid accumulation, compound for staining age spots/diffuse age spots, and remedy for disease with amyloid accumulation
JP2006505610A (ja) 2002-11-05 2006-02-16 イヨン ベアム アプリカスィヨン エッス．アー． １８−ｆ標識放射性製剤の安定化
GB0229695D0 (en) 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
NZ548098A (en) 2003-12-31 2010-05-28 Schering Plough Ltd Control of parasites in animals by the use of imidazo[1,2-b]pyridazine derivatives
US20070031328A1 (en) * 2005-06-24 2007-02-08 Kung Hank F Radiolabeled-pegylation of ligands for use as imaging agents
US20080219922A1 (en) * 2005-09-12 2008-09-11 Goodman Mark M Alzheimer's Disease Imaging Agents
ATE535527T1 (de) 2006-05-19 2011-12-15 Nihon Mediphysics Co Ltd Verbindung mit affinität zu amyloid
TW200918102A (en) 2007-10-24 2009-05-01 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
CA2704027A1 (en) 2007-10-26 2009-04-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
EP2216050A4 (de) 2007-10-30 2012-11-21 Nihon Mediphysics Co Ltd Verwendung von neuen verbindungen mit amyloid-affinität und herstellungsverfahren dafür

Also Published As

Publication number Publication date
CN101501033A (zh) 2009-08-05
CN101501033B (zh) 2012-08-01
CA2655826A1 (en) 2007-12-27
AU2007261985B2 (en) 2012-04-19
KR20090025282A (ko) 2009-03-10
WO2007148755A1 (ja) 2007-12-27
US20100092387A1 (en) 2010-04-15
EP2042501A4 (de) 2012-11-21
AU2007261985A1 (en) 2007-12-27
NO20090233L (no) 2009-02-11
US8277777B2 (en) 2012-10-02
IL196046A0 (en) 2009-09-01
EP2042501A1 (de) 2009-04-01
EP2042501B1 (de) 2017-04-12

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