HK1131613A1 - Salts of benzimidazolyl pyridyl ethers and formulations thereof - Google Patents

Salts of benzimidazolyl pyridyl ethers and formulations thereof

Info

Publication number
HK1131613A1
HK1131613A1 HK09110555.7A HK09110555A HK1131613A1 HK 1131613 A1 HK1131613 A1 HK 1131613A1 HK 09110555 A HK09110555 A HK 09110555A HK 1131613 A1 HK1131613 A1 HK 1131613A1
Authority
HK
Hong Kong
Prior art keywords
salts
formulations
pyridyl ethers
benzimidazolyl pyridyl
benzimidazolyl
Prior art date
Application number
HK09110555.7A
Other languages
English (en)
Inventor
Rampurna Gullapalli
Ahmad Hashash
Piotr H Karpinski
Kangwen L Lin
Eric M Loeser
Augustus O Okhamafe
Paul Allen Sutton
Eduardo Sy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1131613A1 publication Critical patent/HK1131613A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK09110555.7A 2006-08-30 2009-11-12 Salts of benzimidazolyl pyridyl ethers and formulations thereof HK1131613A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84117706P 2006-08-30 2006-08-30
US95446607P 2007-08-07 2007-08-07
PCT/US2007/019152 WO2008027523A2 (en) 2006-08-30 2007-08-30 Salts of benzimidazolyl pyridyl ethers and formulations thereof

Publications (1)

Publication Number Publication Date
HK1131613A1 true HK1131613A1 (en) 2010-01-29

Family

ID=39027583

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09110555.7A HK1131613A1 (en) 2006-08-30 2009-11-12 Salts of benzimidazolyl pyridyl ethers and formulations thereof

Country Status (34)

Country Link
US (2) US8202998B2 (de)
EP (1) EP2059518B1 (de)
JP (1) JP5279712B2 (de)
KR (1) KR20090043542A (de)
CN (1) CN101516870B (de)
AT (1) ATE504584T1 (de)
AU (1) AU2007290388B2 (de)
BR (1) BRPI0716243A2 (de)
CA (1) CA2660376C (de)
CL (1) CL2007002533A1 (de)
CO (1) CO6150180A2 (de)
CY (1) CY1112187T1 (de)
DE (1) DE602007013774D1 (de)
DK (1) DK2059518T3 (de)
ES (1) ES2360968T3 (de)
GT (1) GT200900045A (de)
HK (1) HK1131613A1 (de)
HR (1) HRP20110311T1 (de)
IL (1) IL196811A (de)
JO (1) JO2702B1 (de)
MA (1) MA30711B1 (de)
MX (1) MX2009002279A (de)
MY (1) MY161829A (de)
NO (1) NO20091236L (de)
NZ (1) NZ574620A (de)
PE (2) PE20080766A1 (de)
PL (1) PL2059518T3 (de)
PT (1) PT2059518E (de)
RU (1) RU2457206C2 (de)
SI (1) SI2059518T1 (de)
TN (1) TN2009000068A1 (de)
TW (1) TW200819438A (de)
WO (1) WO2008027523A2 (de)
ZA (1) ZA200900664B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080766A1 (es) * 2006-08-30 2008-06-15 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen
CN101679372A (zh) * 2007-03-02 2010-03-24 诺瓦提斯公司 Raf激酶抑制剂的固体形式
US20110092546A1 (en) * 2008-06-13 2011-04-21 Novartis Ag Substituted benzimidazoles for neurofibromatosis
SI2391366T1 (sl) * 2009-01-29 2013-01-31 Novartis Ag Substituirani benzimidazoli za zdravljenje astrocitomov
WO2011044072A1 (en) 2009-10-05 2011-04-14 Novartis Ag Combination of raf-265 and an activator of ampk for use in the treatment of a proliferative disease
MA34806B1 (fr) * 2010-12-03 2014-01-02 Novartis Ag Compositions pharmaceutiques
IL293268A (en) * 2019-12-02 2022-07-01 Astrazeneca Ab Solid pharmaceutical formulations of 6-(2-chloro-6-methylpyridin-4-yl)-5-(-4-fluorophenyl)-1,2,4-triazine-3-amine
WO2022083741A1 (zh) * 2020-10-23 2022-04-28 上海辉启生物医药科技有限公司 吡唑并吡啶类化合物或其盐及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8299108B2 (en) * 2002-03-29 2012-10-30 Novartis Ag Substituted benzazoles and methods of their use as inhibitors of raf kinase
US7071216B2 (en) * 2002-03-29 2006-07-04 Chiron Corporation Substituted benz-azoles and methods of their use as inhibitors of Raf kinase
US20060189619A1 (en) 2005-02-24 2006-08-24 Wyeth 3-({4-[2-(4-Tert-butylphenyl)-1h-benzimidazol-4-yl]piperazin-1-yl}methyl)pyrido[2,3-b]]pyrazi ne compounds
PE20070427A1 (es) * 2005-08-30 2007-04-21 Novartis Ag Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
US7731795B2 (en) 2005-12-02 2010-06-08 Clemson University Rhombohedral fluoroberyllium borate crystals and hydrothermal growth thereof for use in laser and non-linear optical applications and devices
SI2046292T1 (sl) * 2006-07-21 2010-06-30 Novartis Ag Formulacije za benzimidazolil piridil etre
PE20080766A1 (es) * 2006-08-30 2008-06-15 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen

Also Published As

Publication number Publication date
TN2009000068A1 (en) 2010-08-19
JP5279712B2 (ja) 2013-09-04
KR20090043542A (ko) 2009-05-06
BRPI0716243A2 (pt) 2013-09-03
IL196811A (en) 2013-03-24
PE20130814A1 (es) 2013-08-08
IL196811A0 (en) 2009-11-18
TW200819438A (en) 2008-05-01
MX2009002279A (es) 2009-03-20
EP2059518A2 (de) 2009-05-20
WO2008027523A3 (en) 2008-04-10
PE20080766A1 (es) 2008-06-15
CY1112187T1 (el) 2015-12-09
CA2660376A1 (en) 2008-03-06
US8501785B2 (en) 2013-08-06
GT200900045A (es) 2010-06-14
HRP20110311T1 (hr) 2011-08-31
EP2059518B1 (de) 2011-04-06
JP2010502622A (ja) 2010-01-28
CL2007002533A1 (es) 2008-02-08
CO6150180A2 (es) 2010-04-20
JO2702B1 (en) 2013-03-03
CA2660376C (en) 2014-04-15
CN101516870A (zh) 2009-08-26
AU2007290388B2 (en) 2011-07-14
MA30711B1 (fr) 2009-09-01
US8202998B2 (en) 2012-06-19
US20100168060A1 (en) 2010-07-01
MY161829A (en) 2017-05-15
US20120308651A1 (en) 2012-12-06
NZ574620A (en) 2011-05-27
WO2008027523A2 (en) 2008-03-06
ZA200900664B (en) 2009-12-30
DE602007013774D1 (de) 2011-05-19
DK2059518T3 (da) 2011-05-16
ES2360968T3 (es) 2011-06-10
SI2059518T1 (sl) 2011-06-30
RU2457206C2 (ru) 2012-07-27
PL2059518T3 (pl) 2011-09-30
PT2059518E (pt) 2011-07-11
NO20091236L (no) 2009-03-27
CN101516870B (zh) 2013-09-11
ATE504584T1 (de) 2011-04-15
AU2007290388A1 (en) 2008-03-06
RU2009111384A (ru) 2010-10-10

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150830