HK1126475A1 - Tetracyclic steroid derivatives useful as progesterone receptor modulators - Google Patents

Tetracyclic steroid derivatives useful as progesterone receptor modulators

Info

Publication number
HK1126475A1
HK1126475A1 HK09104797.8A HK09104797A HK1126475A1 HK 1126475 A1 HK1126475 A1 HK 1126475A1 HK 09104797 A HK09104797 A HK 09104797A HK 1126475 A1 HK1126475 A1 HK 1126475A1
Authority
HK
Hong Kong
Prior art keywords
steroid derivatives
receptor modulators
progesterone receptor
derivatives useful
tetracyclic steroid
Prior art date
Application number
HK09104797.8A
Other languages
English (en)
Inventor
Ningyi Chen
Nareshkumar F Jain
Zhihua Sui
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1126475A1 publication Critical patent/HK1126475A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
HK09104797.8A 2006-02-17 2009-05-26 Tetracyclic steroid derivatives useful as progesterone receptor modulators HK1126475A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77434806P 2006-02-17 2006-02-17
PCT/US2007/062280 WO2007098384A2 (en) 2006-02-17 2007-02-16 Tetracyclic steroid derivatives useful as progesterone receptor modulators

Publications (1)

Publication Number Publication Date
HK1126475A1 true HK1126475A1 (en) 2009-09-04

Family

ID=38290140

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09104797.8A HK1126475A1 (en) 2006-02-17 2009-05-26 Tetracyclic steroid derivatives useful as progesterone receptor modulators

Country Status (16)

Country Link
US (1) US7390831B2 (sl)
EP (1) EP1996571B1 (sl)
JP (1) JP5230451B2 (sl)
CN (1) CN101421261B (sl)
AT (1) ATE485286T1 (sl)
AU (1) AU2007217097B2 (sl)
CA (1) CA2642763A1 (sl)
CY (1) CY1111110T1 (sl)
DE (1) DE602007009945D1 (sl)
DK (1) DK1996571T3 (sl)
ES (1) ES2353133T3 (sl)
HK (1) HK1126475A1 (sl)
PL (1) PL1996571T3 (sl)
PT (1) PT1996571E (sl)
SI (1) SI1996571T1 (sl)
WO (1) WO2007098384A2 (sl)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2077752B1 (sl) * 1970-02-11 1973-03-16 Roussel Uclaf

Also Published As

Publication number Publication date
EP1996571B1 (en) 2010-10-20
WO2007098384A2 (en) 2007-08-30
SI1996571T1 (sl) 2011-02-28
CA2642763A1 (en) 2007-08-30
AU2007217097A1 (en) 2007-08-30
DK1996571T3 (da) 2011-02-07
US20070197634A1 (en) 2007-08-23
ATE485286T1 (de) 2010-11-15
JP2009527492A (ja) 2009-07-30
DE602007009945D1 (de) 2010-12-02
CN101421261A (zh) 2009-04-29
ES2353133T3 (es) 2011-02-25
CN101421261B (zh) 2013-01-23
PL1996571T3 (pl) 2011-04-29
CY1111110T1 (el) 2015-06-11
AU2007217097B2 (en) 2012-12-06
US7390831B2 (en) 2008-06-24
WO2007098384A3 (en) 2007-10-04
PT1996571E (pt) 2010-12-07
JP5230451B2 (ja) 2013-07-10
EP1996571A2 (en) 2008-12-03

Similar Documents

Publication Publication Date Title
SI1989218T1 (sl) 17- fosforjevi steroidni derivati, koristni kot progesteronski receptorski modulatorji
WO2007098381A3 (en) 11-phosphorous steroid derivatives useful as progesterone receptor modulators
WO2010054158A3 (en) Steroid modulators of glucocorticoid receptor
TW200621725A (en) Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
TW200621235A (en) Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms)
MY142850A (en) Novel indole derivatives as selective androgen receptor modulators (sarms)
MX2013002975A (es) Moduladores de receptores de estrogenos y usos de los mismos.
TW200624424A (en) Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms)
WO2006066011A3 (en) Compounds and compositions as modulators of steroidal receptors and calcium channel activities
WO2006015259A3 (en) Compounds and compositions as modulators of steroid hormone nuclear receptors
HK1139930A1 (en) Cyclopamine lactam analogs and methods of use thereof
WO2006130416A3 (en) Novel 3-spirocyclic indolyl derivatives useful as orl-1 receptor modulators
MY143211A (en) Novel indole derivatives as selective androgen receptor modulators (sarms)
TW200604170A (en) Novel indole derivatives as selective androgen receptor modulators (SARMs)
MY148780A (en) Tricyclic compounds, compositions, and methods
UA94441C2 (ru) 2-замещенные бензимидазолы как селективные модуляторы рецептора андрогена (sarms)
PH12014501079A1 (en) 4 - pregenen- 11ss - 17 - 21 -triol-3, 20 -dione derivatives for the treatment of ocular conditions
UA105920C2 (uk) ПОХІДНІ СПОЛУК СТЕРОЇДАЛ[3,2-с]ПІРАЗОЛУ З ГЛЮКОКОРТИКОЇДНОЮ АКТИВНІСТЮ
ATE473741T1 (de) Neue imidazolopyrazolderivate als selektive androgen-rezeptor-modulatoren
WO2008109719A3 (en) Steroids derivatives as selective progesterone receptor modulators
WO2008152094A3 (en) Substituted acetamides as modulators of the ep2 receptor
HK1126475A1 (en) Tetracyclic steroid derivatives useful as progesterone receptor modulators
WO2009140225A3 (en) Anti-inflammatory and immunosuppresive glucocorticoid steroids
WO2007098388A3 (en) Oxa-steroids derivatives as selective progesterone receptor modulators
PT1812417E (pt) Novos derivados de 2h-cromeno como moduladores selectivos do receptor de estrogénio

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150216