HK1121142A1 - Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia - Google Patents

Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia

Info

Publication number
HK1121142A1
HK1121142A1 HK09100247.2A HK09100247A HK1121142A1 HK 1121142 A1 HK1121142 A1 HK 1121142A1 HK 09100247 A HK09100247 A HK 09100247A HK 1121142 A1 HK1121142 A1 HK 1121142A1
Authority
HK
Hong Kong
Prior art keywords
functional
ibs
treatment
compounds useful
gastrointestinal disorders
Prior art date
Application number
HK09100247.2A
Other languages
English (en)
Inventor
Rolf Bergman
Sara Holmqvist
Unge Sverker Von
Original Assignee
Albireo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Albireo Ab filed Critical Albireo Ab
Publication of HK1121142A1 publication Critical patent/HK1121142A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)
HK09100247.2A 2005-09-29 2009-02-03 Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia HK1121142A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0502150 2005-09-29
PCT/SE2006/001092 WO2007037743A1 (en) 2005-09-29 2006-09-27 Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia

Publications (1)

Publication Number Publication Date
HK1121142A1 true HK1121142A1 (en) 2009-04-17

Family

ID=37900052

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09100247.2A HK1121142A1 (en) 2005-09-29 2009-02-03 Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, ibs and functional dyspepsia

Country Status (16)

Country Link
US (1) US8288370B2 (ja)
EP (1) EP1940845B1 (ja)
JP (1) JP5139985B2 (ja)
KR (1) KR20080077096A (ja)
CN (1) CN101316846A (ja)
AR (1) AR057828A1 (ja)
AU (1) AU2006295473B2 (ja)
BR (1) BRPI0616581A2 (ja)
CA (1) CA2624491C (ja)
ES (1) ES2426259T3 (ja)
HK (1) HK1121142A1 (ja)
NO (1) NO20081983L (ja)
TW (1) TW200745122A (ja)
UY (1) UY29818A1 (ja)
WO (1) WO2007037743A1 (ja)
ZA (1) ZA200802645B (ja)

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WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
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CN104873482B (zh) * 2015-05-05 2017-12-01 青岛市市立医院 一种抗慢性心力衰竭的药物组合物
CN104958297A (zh) * 2015-06-03 2015-10-07 周玉梅 一种用于麻醉镇静催眠的药物组合物及其应用
CN105663133B (zh) * 2016-03-07 2019-06-25 青岛市肿瘤医院 一种抑制淋巴瘤细胞增殖的药物组合物及其应用
JP2019509485A (ja) * 2016-03-09 2019-04-04 バイオメリカ・インコーポレイテッドＢｉｏｍｅｒｉｃａ， Ｉｎｃ． 機能性消化不良感受性試験の組成物、デバイスおよび方法

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EP1940845B1 (en) 2013-06-12
BRPI0616581A2 (pt) 2011-06-21
ES2426259T3 (es) 2013-10-22
US20100311713A1 (en) 2010-12-09
US8288370B2 (en) 2012-10-16
AU2006295473A1 (en) 2007-04-05
TW200745122A (en) 2007-12-16
CA2624491A1 (en) 2007-04-05
CN101316846A (zh) 2008-12-03
ZA200802645B (en) 2008-12-31
CA2624491C (en) 2014-01-14
AU2006295473B2 (en) 2011-11-10
EP1940845A4 (en) 2010-11-17
JP2009510055A (ja) 2009-03-12
UY29818A1 (es) 2007-04-30
EP1940845A1 (en) 2008-07-09
JP5139985B2 (ja) 2013-02-06
AR057828A1 (es) 2007-12-19
KR20080077096A (ko) 2008-08-21
NO20081983L (no) 2008-06-27

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