HK1114107A1 - Mutant il-10 - Google Patents
Mutant il-10Info
- Publication number
- HK1114107A1 HK1114107A1 HK08109210.7A HK08109210A HK1114107A1 HK 1114107 A1 HK1114107 A1 HK 1114107A1 HK 08109210 A HK08109210 A HK 08109210A HK 1114107 A1 HK1114107 A1 HK 1114107A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- retain
- mutant
- hemoatopoeitic
- polypeptides
- wild
- Prior art date
Links
Classifications
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Oncology (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68627205P | 2005-05-31 | 2005-05-31 | |
PCT/US2006/020863 WO2006130580A2 (en) | 2005-05-31 | 2006-05-26 | Mutant il-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1114107A1 true HK1114107A1 (en) | 2008-10-24 |
Family
ID=37482214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08109210.7A HK1114107A1 (en) | 2005-05-31 | 2008-08-19 | Mutant il-10 |
Country Status (8)
Country | Link |
---|---|
US (1) | US7749490B2 (de) |
EP (1) | EP1891103B1 (de) |
JP (2) | JP4992025B2 (de) |
AT (1) | ATE452908T1 (de) |
CA (1) | CA2609543C (de) |
DE (1) | DE602006011311D1 (de) |
HK (1) | HK1114107A1 (de) |
WO (1) | WO2006130580A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1324779B1 (de) | 2000-09-29 | 2011-07-20 | Schering Corporation | Pegyliertes interleukin 10 |
US7261882B2 (en) * | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
ES2696824T3 (es) * | 2005-05-31 | 2019-01-18 | Univ Colorado Regents | Métodos para suministrar genes |
AU2007314501B2 (en) | 2006-09-28 | 2013-05-23 | Merck Sharp & Dohme Corp. | Use of pegylated IL-10 to treat cancer |
US8691205B2 (en) | 2008-12-17 | 2014-04-08 | Merck Sharp & Dohme Corporation | Mono- and di-PEG IL-10 production; and uses |
CN108129574A (zh) | 2011-11-08 | 2018-06-08 | Umc乌德勒支控股有限公司 | 包括白细胞介素10和白细胞介素4的融合蛋白 |
US20150044281A1 (en) * | 2012-01-06 | 2015-02-12 | The Regents Of The University Of Colorado, A Body Corporate | Methods for the treatment of multiple sclerosis and other demyelinating disorders |
US9943568B2 (en) * | 2013-04-18 | 2018-04-17 | Armo Biosciences, Inc. | Methods of using pegylated interleukin-10 for treating cancer |
US20160068583A1 (en) * | 2013-04-24 | 2016-03-10 | Armo Biosciences, Inc. | Interleukin-10 Compositions and Uses Thereof |
ES2688206T3 (es) | 2013-06-17 | 2018-10-31 | Armo Biosciences, Inc. | Procedimiento de evaluación de la identidad y la estabilidad de proteínas |
RS57974B1 (sr) * | 2013-07-18 | 2019-01-31 | Xalud Therapeutics Inc | Sastavi za lečenje inflamatornog oboljenja zglobova |
CN105658232A (zh) | 2013-08-30 | 2016-06-08 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
WO2015070060A1 (en) | 2013-11-11 | 2015-05-14 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US10293043B2 (en) | 2014-06-02 | 2019-05-21 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
MX2017004838A (es) | 2014-10-14 | 2017-10-16 | Armo Biosciences Inc | Composiciones de interleucina-15 y usos de estas. |
AU2015336101A1 (en) | 2014-10-22 | 2017-04-20 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
EP3302547A1 (de) | 2015-05-28 | 2018-04-11 | Armo Biosciences, Inc. | Pegyliertes interleukin-10 zur behandlung von krebs |
EP3341012A4 (de) | 2015-08-25 | 2019-03-20 | Armo Biosciences, Inc. | Verfahren zur verwendung von interleukin-10 zur behandlung von erkrankungen und leiden |
WO2017160599A1 (en) | 2016-03-14 | 2017-09-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of cd300b antagonists to treat sepsis and septic shock |
CN109477085B (zh) * | 2016-04-22 | 2023-08-01 | 萨鲁德医疗公司 | 增强白细胞介素10的抗炎作用的方法和组合物 |
TW202033766A (zh) * | 2018-11-26 | 2020-09-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種人白細胞介素10變體及其衍生物 |
EP3927728A2 (de) | 2019-02-21 | 2021-12-29 | Xencor, Inc. | Ungezielte und zielgerichtete il-10-fc-fusionsproteine |
EP3955956A1 (de) | 2019-04-19 | 2022-02-23 | Synerkine Pharma B.V. | Therapeutische vernetzung von cytokinrezeptoren |
MX2022014890A (es) * | 2020-05-28 | 2023-02-22 | Univ Leland Stanford Junior | Polipéptidos de interleucina-10 modificados y usos de los mismos. |
WO2023114958A1 (en) * | 2021-12-16 | 2023-06-22 | Xalud Therapeutics, Inc. | Dosing regimen for il-10 encoding expression construct |
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US6428985B1 (en) | 1998-12-02 | 2002-08-06 | The Regents Of The University Of Michigan | Immunosuppressive structural definition of IL-10 |
WO2001058950A1 (en) * | 2000-02-11 | 2001-08-16 | Maxygen Aps | Improved interleukin 10 |
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JP2012130344A (ja) | 2012-07-12 |
CA2609543C (en) | 2015-03-24 |
DE602006011311D1 (de) | 2010-02-04 |
EP1891103B1 (de) | 2009-12-23 |
ATE452908T1 (de) | 2010-01-15 |
CA2609543A1 (en) | 2006-12-07 |
JP4992025B2 (ja) | 2012-08-08 |
US7749490B2 (en) | 2010-07-06 |
US20090035256A1 (en) | 2009-02-05 |
EP1891103A2 (de) | 2008-02-27 |
WO2006130580A3 (en) | 2007-04-19 |
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