CA2609543C - Mutant il-10 - Google Patents
Mutant il-10 Download PDFInfo
- Publication number
- CA2609543C CA2609543C CA2609543A CA2609543A CA2609543C CA 2609543 C CA2609543 C CA 2609543C CA 2609543 A CA2609543 A CA 2609543A CA 2609543 A CA2609543 A CA 2609543A CA 2609543 C CA2609543 C CA 2609543C
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- Prior art keywords
- aav
- vector
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- mutant
- vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
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- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68627205P | 2005-05-31 | 2005-05-31 | |
US60/686,272 | 2005-05-31 | ||
PCT/US2006/020863 WO2006130580A2 (en) | 2005-05-31 | 2006-05-26 | Mutant il-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2609543A1 CA2609543A1 (en) | 2006-12-07 |
CA2609543C true CA2609543C (en) | 2015-03-24 |
Family
ID=37482214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2609543A Active CA2609543C (en) | 2005-05-31 | 2006-05-26 | Mutant il-10 |
Country Status (8)
Country | Link |
---|---|
US (1) | US7749490B2 (de) |
EP (1) | EP1891103B1 (de) |
JP (2) | JP4992025B2 (de) |
AT (1) | ATE452908T1 (de) |
CA (1) | CA2609543C (de) |
DE (1) | DE602006011311D1 (de) |
HK (1) | HK1114107A1 (de) |
WO (1) | WO2006130580A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7052686B2 (en) | 2000-09-29 | 2006-05-30 | Schering Corporation | Pegylated interleukin-10 |
US7261882B2 (en) * | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
SI2816118T1 (sl) * | 2005-05-31 | 2019-01-31 | The Regents Of The University Of Colorado, A Body Corporate | Metode za dostavo genov |
US20080081031A1 (en) | 2006-09-28 | 2008-04-03 | Schering Corporation | Use of Pegylated IL-10 to Treat Cancer |
DK2379115T3 (da) | 2008-12-17 | 2018-01-29 | Merck Sharp & Dohme | Fremstilling og anvendelse af mono- og di-PEG-IL-10 |
HUE038668T2 (hu) | 2011-11-08 | 2018-11-28 | Umc Utrecht Holding Bv | Interleukin-4-et és interleukin-10-et tartalmazó fúziós fehérje |
WO2013103966A1 (en) * | 2012-01-06 | 2013-07-11 | The Regents Of The University Of Colorado, A Body Corporate | Methods for the treatment of multiple sclerosis and other demyelinating disorders |
BR112015026122A8 (pt) * | 2013-04-18 | 2020-01-21 | Armo Biosciences Inc | agente de polietileno glicol-il-10 (peg-il-10), seu uso, composição farmacêutica, contentor estéril e kit |
AU2014257123A1 (en) * | 2013-04-24 | 2015-10-15 | Armo Biosciences, Inc. | Interleukin-10 compositions and uses thereof |
US9823255B2 (en) | 2013-06-17 | 2017-11-21 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
US10512672B2 (en) * | 2013-07-18 | 2019-12-24 | Xalud Therapeutics, Inc. | Methods for the treatment of inflammatory joint disease |
US10010588B2 (en) | 2013-08-30 | 2018-07-03 | Armo Biosciences, Inc. | Methods of using pegylated interleukin-10 for treating hyperlipidemia |
US11413332B2 (en) | 2013-11-11 | 2022-08-16 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US10293043B2 (en) | 2014-06-02 | 2019-05-21 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
WO2016060996A2 (en) | 2014-10-14 | 2016-04-21 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
WO2016064817A1 (en) | 2014-10-22 | 2016-04-28 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
AU2016268403A1 (en) | 2015-05-28 | 2017-12-07 | Armo Biosciences, Inc. | Pegylated interleukin-10 for use in treating cancer |
EP3341012A4 (de) | 2015-08-25 | 2019-03-20 | Armo Biosciences, Inc. | Verfahren zur verwendung von interleukin-10 zur behandlung von erkrankungen und leiden |
WO2017160599A1 (en) | 2016-03-14 | 2017-09-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of cd300b antagonists to treat sepsis and septic shock |
CN109477085B (zh) * | 2016-04-22 | 2023-08-01 | 萨鲁德医疗公司 | 增强白细胞介素10的抗炎作用的方法和组合物 |
TW202033766A (zh) * | 2018-11-26 | 2020-09-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種人白細胞介素10變體及其衍生物 |
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US6428985B1 (en) | 1998-12-02 | 2002-08-06 | The Regents Of The University Of Michigan | Immunosuppressive structural definition of IL-10 |
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DE602006011311D1 (de) | 2010-02-04 |
CA2609543A1 (en) | 2006-12-07 |
ATE452908T1 (de) | 2010-01-15 |
WO2006130580A3 (en) | 2007-04-19 |
HK1114107A1 (en) | 2008-10-24 |
US7749490B2 (en) | 2010-07-06 |
JP2012130344A (ja) | 2012-07-12 |
WO2006130580A2 (en) | 2006-12-07 |
US20090035256A1 (en) | 2009-02-05 |
EP1891103A2 (de) | 2008-02-27 |
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