HK1112612A1 - 3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline forms - Google Patents

3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline forms

Info

Publication number
HK1112612A1
HK1112612A1 HK08107521.5A HK08107521A HK1112612A1 HK 1112612 A1 HK1112612 A1 HK 1112612A1 HK 08107521 A HK08107521 A HK 08107521A HK 1112612 A1 HK1112612 A1 HK 1112612A1
Authority
HK
Hong Kong
Prior art keywords
cyclohex
dimethylamino
methyl
crystalline forms
phenol maleate
Prior art date
Application number
HK08107521.5A
Other languages
English (en)
Inventor
Martin Szelagiewicz
Wolfgang Hell
Raumer Markus Von
Paul Susan Margaret De
Joerg Berghausen
Michael Gruss
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of HK1112612A1 publication Critical patent/HK1112612A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HK08107521.5A 2005-07-22 2008-07-08 3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline forms HK1112612A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005034974A DE102005034974A1 (de) 2005-07-22 2005-07-22 Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen
PCT/EP2006/007160 WO2007009792A1 (de) 2005-07-22 2006-07-20 3-(2-(dimethylamino)methyl-(cyclohex-1-yl))phenol-maleat und dessen kristalline formen

Publications (1)

Publication Number Publication Date
HK1112612A1 true HK1112612A1 (en) 2008-09-12

Family

ID=37084866

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08107521.5A HK1112612A1 (en) 2005-07-22 2008-07-08 3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline forms

Country Status (26)

Country Link
EP (1) EP1881956B1 (pt)
JP (1) JP5205259B2 (pt)
KR (1) KR20080033436A (pt)
CN (1) CN101228110A (pt)
AR (1) AR057674A1 (pt)
AT (1) ATE431332T1 (pt)
AU (1) AU2006271856B2 (pt)
BR (1) BRPI0614057A2 (pt)
CA (1) CA2615926A1 (pt)
CY (1) CY1109208T1 (pt)
DE (2) DE102005034974A1 (pt)
DK (1) DK1881956T3 (pt)
EC (1) ECSP088088A (pt)
ES (1) ES2326493T3 (pt)
HK (1) HK1112612A1 (pt)
HR (1) HRP20090412T1 (pt)
IL (1) IL188897A (pt)
MX (1) MX2008000743A (pt)
NO (1) NO20080826L (pt)
PE (1) PE20070368A1 (pt)
PL (1) PL1881956T3 (pt)
PT (1) PT1881956E (pt)
RU (1) RU2434845C2 (pt)
SI (1) SI1881956T1 (pt)
WO (1) WO2007009792A1 (pt)
ZA (1) ZA200801703B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008000070A1 (es) * 2007-01-17 2008-07-25 Lg Life Sciences Ltd Monosal del acido maleico (3-[({1-[(2-amino-9h-purin-9-il)metil]ciclopropil}oxi)metil]-8,8-dimetil-3,7-dioxo-2,4,6-trioxa-3 lambda 5-fosfanon-1-il-pivalato; composicion farmaceutica que comprende a dicha monosal; y uso para el tratamiento del virus h
HUE047275T2 (hu) * 2007-12-07 2020-04-28 Gruenenthal Gmbh (1R,2R)-3-(3-dimetil-amino-1-etil-2-metil-propil)-fenol kristályos módosításait tartalmazó gyógyszerek
EP2085081A1 (de) 2008-02-04 2009-08-05 Grünenthal GmbH 3-(2-Dimethylaminomethyl-cyclohexyl)-phenol gegen polyneuropathischen Schmerz

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE10218862A1 (de) * 2002-04-26 2003-11-06 Gruenenthal Gmbh Verfahren zur Chlorierung tertiärer Alkohole
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen

Also Published As

Publication number Publication date
DE102005034974A1 (de) 2007-04-19
AU2006271856B2 (en) 2012-03-01
ATE431332T1 (de) 2009-05-15
MX2008000743A (es) 2008-03-10
NO20080826L (no) 2008-02-20
AR057674A1 (es) 2007-12-12
RU2434845C2 (ru) 2011-11-27
PE20070368A1 (es) 2007-05-12
JP5205259B2 (ja) 2013-06-05
EP1881956B1 (de) 2009-05-13
ZA200801703B (en) 2009-08-26
RU2008106455A (ru) 2009-08-27
CN101228110A (zh) 2008-07-23
IL188897A (en) 2012-12-31
ECSP088088A (es) 2008-02-20
EP1881956A1 (de) 2008-01-30
DK1881956T3 (da) 2009-09-07
PL1881956T3 (pl) 2009-10-30
AU2006271856A1 (en) 2007-01-25
DE502006003728D1 (de) 2009-06-25
JP2009502757A (ja) 2009-01-29
CY1109208T1 (el) 2014-07-02
PT1881956E (pt) 2009-06-26
SI1881956T1 (sl) 2009-10-31
CA2615926A1 (en) 2007-01-25
HRP20090412T1 (hr) 2009-09-30
BRPI0614057A2 (pt) 2012-12-11
WO2007009792A1 (de) 2007-01-25
KR20080033436A (ko) 2008-04-16
ES2326493T3 (es) 2009-10-13
IL188897A0 (en) 2008-04-13

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140720