HK1089446A1 - Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligands - Google Patents
Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligandsInfo
- Publication number
- HK1089446A1 HK1089446A1 HK06111339A HK06111339A HK1089446A1 HK 1089446 A1 HK1089446 A1 HK 1089446A1 HK 06111339 A HK06111339 A HK 06111339A HK 06111339 A HK06111339 A HK 06111339A HK 1089446 A1 HK1089446 A1 HK 1089446A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrimidines
- triazolo
- imidazo
- receptor ligands
- benzodiazepine receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49000603P | 2003-07-25 | 2003-07-25 | |
| US54308304P | 2004-02-09 | 2004-02-09 | |
| PCT/US2004/023794 WO2005012306A2 (en) | 2003-07-25 | 2004-07-23 | Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1089446A1 true HK1089446A1 (en) | 2006-12-01 |
Family
ID=34118813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06111339A HK1089446A1 (en) | 2003-07-25 | 2006-10-17 | Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligands |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7271170B2 (ko) |
| EP (1) | EP1648899B1 (ko) |
| JP (1) | JP2007500130A (ko) |
| KR (1) | KR20060098425A (ko) |
| AR (1) | AR045117A1 (ko) |
| AT (1) | ATE350382T1 (ko) |
| AU (1) | AU2004261591A1 (ko) |
| BR (1) | BRPI0412908A (ko) |
| CA (1) | CA2537331A1 (ko) |
| CY (1) | CY1107565T1 (ko) |
| DE (1) | DE602004004143T2 (ko) |
| DK (1) | DK1648899T3 (ko) |
| ES (1) | ES2278345T3 (ko) |
| HK (1) | HK1089446A1 (ko) |
| IL (1) | IL173265A0 (ko) |
| MX (1) | MXPA06000887A (ko) |
| NZ (1) | NZ544262A (ko) |
| PL (1) | PL1648899T3 (ko) |
| PT (1) | PT1648899E (ko) |
| TW (1) | TW200524937A (ko) |
| WO (1) | WO2005012306A2 (ko) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7482366B2 (en) * | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| CA2524376A1 (en) * | 2003-05-05 | 2004-12-16 | Neurogen Corporation | Substituted imidazolopyrazine and triazolopyrazyne derivatives: gabaa receptor ligands |
| US20080167324A1 (en) * | 2005-03-02 | 2008-07-10 | Yuelian Xu | Thiazolymethyl and Oxazolylmethyl Heteroaryl Derivatives |
| EP1928237A4 (en) | 2005-09-02 | 2011-03-09 | Abbott Lab | NEW HETEROCYCLES BASED ON IMIDAZO |
| JP2010523716A (ja) * | 2007-04-11 | 2010-07-15 | サイプレス バイオサイエンシズ，インク． | ベンゾジアゼピン受容体拮抗薬を用いるダウン症候群の治療 |
| JP2010524953A (ja) * | 2007-04-17 | 2010-07-22 | ブリストル−マイヤーズ スクイブ カンパニー | 縮合ヘテロ環１１−β−ヒドロキシステロイドデヒドロゲナーゼＩ型阻害剤 |
| GB0719803D0 (en) | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| US20090270373A1 (en) * | 2008-04-11 | 2009-10-29 | Cypress Biosciences, Inc. | Treatment of down syndrom with benzodiazepine receptor antagonists |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US544057A (en) * | 1895-08-06 | Bill and letter file | ||
| DE60014339T8 (de) * | 1999-04-02 | 2006-04-27 | Neurogen Corp., Branford | Aryl- und heteroaryl-kondensierte aminoalkyl-imidazol-derivate: selektive modulatoren der gabaa-rezeptoren |
| US6737242B1 (en) | 1999-05-07 | 2004-05-18 | Neurogen Corporation | Methods for screening GABA-modulatory compounds for specified pharmacological activities |
| GB9929687D0 (en) * | 1999-12-15 | 2000-02-09 | Merck Sharp & Dohme | Therapeutic agents |
| US6552037B2 (en) | 2000-06-30 | 2003-04-22 | Neurogen Corporation | 2-Substituted imidazo[1,2-A]pyridine derivatives |
| GB0027561D0 (en) | 2000-11-10 | 2000-12-27 | Merck Sharp & Dohme | Therapeutic agents |
| US6900215B2 (en) * | 2000-12-15 | 2005-05-31 | Merck Sharp & Dohme Ltd. | Imidazo-pyrimidine derivatives as ligands for gaba receptors |
| PA8535601A1 (es) * | 2000-12-21 | 2002-11-28 | Pfizer | Derivados benzimidazol y piridilimidazol como ligandos para gabaa |
| TWI248936B (en) * | 2001-03-21 | 2006-02-11 | Merck Sharp & Dohme | Imidazo-pyrimidine derivatives as ligands for GABA receptors |
| AU2002241139B2 (en) | 2001-03-23 | 2007-09-20 | Merck Sharp & Dohme Limited | Imidazo-pyrimidine derivatives as ligands for GABA receptors |
| IL159811A0 (en) * | 2001-07-13 | 2004-06-20 | Neurogen Corp | Heteroaryl substituted fused bicyclic heteroaryl compounds as gabaa receptor ligands |
| GB0128499D0 (en) * | 2001-11-28 | 2002-01-23 | Merck Sharp & Dohme | Therapeutic agents |
| AU2003245259A1 (en) | 2002-05-02 | 2003-11-17 | Neurogen Corporation | Substituted imidazole derivatives: gabaa receptor ligands |
| WO2004041809A2 (en) | 2002-05-08 | 2004-05-21 | Neurogen Corporation | Substituted imidazolylmethyl pyridine and pyrazine derivatives and their use as gabaa receptor ligands |
| AU2003237881A1 (en) | 2002-05-17 | 2003-12-02 | Neurogen Corporation | Substituted ring-fused imidazole derivates: gabaa receptor ligands |
| CN100579579C (zh) | 2002-10-01 | 2010-01-13 | 诺华疫苗和诊断公司 | 抗癌及抗感染性疾病组合物及其使用方法 |
| DE60307499T2 (de) | 2002-11-08 | 2007-02-01 | Neurogen Corp., Branford | 4-imidazol-1-ylmethylpyrimidinderivate als liganden für gabaa-rezeptoren |
| CA2524376A1 (en) | 2003-05-05 | 2004-12-16 | Neurogen Corporation | Substituted imidazolopyrazine and triazolopyrazyne derivatives: gabaa receptor ligands |
-
2004
- 2004-07-23 US US10/898,690 patent/US7271170B2/en active Active
- 2004-07-23 AU AU2004261591A patent/AU2004261591A1/en not_active Abandoned
- 2004-07-23 DK DK04779031T patent/DK1648899T3/da active
- 2004-07-23 CA CA002537331A patent/CA2537331A1/en not_active Abandoned
- 2004-07-23 JP JP2006521278A patent/JP2007500130A/ja active Pending
- 2004-07-23 DE DE602004004143T patent/DE602004004143T2/de active Active
- 2004-07-23 PL PL04779031T patent/PL1648899T3/pl unknown
- 2004-07-23 WO PCT/US2004/023794 patent/WO2005012306A2/en active IP Right Grant
- 2004-07-23 ES ES04779031T patent/ES2278345T3/es active Active
- 2004-07-23 KR KR1020067001782A patent/KR20060098425A/ko not_active Application Discontinuation
- 2004-07-23 PT PT04779031T patent/PT1648899E/pt unknown
- 2004-07-23 NZ NZ544262A patent/NZ544262A/xx unknown
- 2004-07-23 AT AT04779031T patent/ATE350382T1/de not_active IP Right Cessation
- 2004-07-23 EP EP04779031A patent/EP1648899B1/en not_active Not-in-force
- 2004-07-23 MX MXPA06000887A patent/MXPA06000887A/es active IP Right Grant
- 2004-07-23 BR BRPI0412908-3A patent/BRPI0412908A/pt not_active IP Right Cessation
- 2004-07-26 TW TW093122247A patent/TW200524937A/zh unknown
- 2004-07-26 AR ARP040102649A patent/AR045117A1/es unknown
-
2006
- 2006-01-19 IL IL173265A patent/IL173265A0/en unknown
- 2006-10-17 HK HK06111339A patent/HK1089446A1/xx not_active IP Right Cessation
-
2007
- 2007-02-26 CY CY20071100262T patent/CY1107565T1/el unknown
- 2007-09-14 US US11/855,386 patent/US20080139580A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE350382T1 (de) | 2007-01-15 |
| AR045117A1 (es) | 2005-10-19 |
| CA2537331A1 (en) | 2005-02-10 |
| PL1648899T3 (pl) | 2007-06-29 |
| BRPI0412908A (pt) | 2006-09-26 |
| DK1648899T3 (da) | 2007-04-02 |
| MXPA06000887A (es) | 2006-04-19 |
| AU2004261591A1 (en) | 2005-02-10 |
| US20080139580A1 (en) | 2008-06-12 |
| EP1648899A2 (en) | 2006-04-26 |
| US20050038043A1 (en) | 2005-02-17 |
| DE602004004143D1 (de) | 2007-02-15 |
| EP1648899B1 (en) | 2007-01-03 |
| JP2007500130A (ja) | 2007-01-11 |
| PT1648899E (pt) | 2007-03-30 |
| CY1107565T1 (el) | 2013-03-13 |
| KR20060098425A (ko) | 2006-09-18 |
| IL173265A0 (en) | 2006-06-11 |
| WO2005012306A3 (en) | 2005-04-14 |
| WO2005012306A2 (en) | 2005-02-10 |
| US7271170B2 (en) | 2007-09-18 |
| DE602004004143T2 (de) | 2007-10-11 |
| TW200524937A (en) | 2005-08-01 |
| ES2278345T3 (es) | 2007-08-01 |
| NZ544262A (en) | 2009-06-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1072432A1 (en) | Thiadiazoledioxides and thiadiazoleoxides as cxc- and cc-chemokine receptor ligands | |
| ZA200507350B (en) | Cannabinoid receptor ligands and uses thereof | |
| IL172026A0 (en) | Cannabinoid receptor ligands and uses thereof | |
| AU8066701A (en) | Capsaicin receptor ligands | |
| EP1522237A4 (en) | MATTRESS | |
| EP1547488A4 (en) | SEAT | |
| EP1552981A4 (en) | SEAT STRUCTURE | |
| HK1089446A1 (en) | Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligands | |
| GB0220922D0 (en) | Improved mat | |
| IL173337A0 (en) | Receptor | |
| AU2003283562A8 (en) | Ligands | |
| GB0310865D0 (en) | Gastrin and cholecystokinin receptor ligands | |
| SI1648899T1 (sl) | Imidazo-pirimidini in triazolo-pirimidini: benzodiazepinski receptorski ligandi | |
| GB2389525B (en) | Mat | |
| GB0313894D0 (en) | Seat | |
| GB0325206D0 (en) | Mat | |
| GB0310864D0 (en) | Gastrin and cholecystokinin receptor ligands | |
| GB0211205D0 (en) | Receptor and ligand | |
| GB0211204D0 (en) | Receptor and its ligand | |
| GB0308398D0 (en) | Mat | |
| GB0321998D0 (en) | Receptor | |
| ZA200600676B (en) | Pyridazinyl-piperazines and their use as histamine H3 receptor ligands | |
| AU2863P (en) | Balazsilma Verbena xhybrida | |
| AU2864P (en) | Balazrasp Verbena xhybrida | |
| AU2871P (en) | Balazpico Verbena xhybrida |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110723 |