HK1076227A1 - Compositions and methods for liver growth and liver protection - Google Patents
Compositions and methods for liver growth and liver protectionInfo
- Publication number
- HK1076227A1 HK1076227A1 HK05109684.7A HK05109684A HK1076227A1 HK 1076227 A1 HK1076227 A1 HK 1076227A1 HK 05109684 A HK05109684 A HK 05109684A HK 1076227 A1 HK1076227 A1 HK 1076227A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- liver
- compositions
- methods
- growth
- protection
- Prior art date
Links
- 210000004185 liver Anatomy 0.000 title 2
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38663702P | 2002-06-05 | 2002-06-05 | |
PCT/US2003/017591 WO2003103581A2 (en) | 2002-06-05 | 2003-06-05 | Compositions and methods for liver growth and liver protection |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1076227A1 true HK1076227A1 (en) | 2006-01-13 |
Family
ID=29736189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK05109684.7A HK1076227A1 (en) | 2002-06-05 | 2005-10-31 | Compositions and methods for liver growth and liver protection |
Country Status (8)
Country | Link |
---|---|
US (2) | US7700571B2 (xx) |
EP (2) | EP1531676B1 (xx) |
JP (2) | JP5111729B2 (xx) |
AU (1) | AU2003251397B2 (xx) |
CA (1) | CA2486270C (xx) |
HK (1) | HK1076227A1 (xx) |
IL (2) | IL165392A0 (xx) |
WO (1) | WO2003103581A2 (xx) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2410887C (en) | 2000-06-02 | 2012-07-24 | Bracco Research Usa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
US8263739B2 (en) | 2000-06-02 | 2012-09-11 | Bracco Suisse Sa | Compounds for targeting endothelial cells, compositions containing the same and methods for their use |
US20050123925A1 (en) | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US7794693B2 (en) | 2002-03-01 | 2010-09-14 | Bracco International B.V. | Targeting vector-phospholipid conjugates |
US20050100963A1 (en) | 2002-03-01 | 2005-05-12 | Dyax Corporation | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
WO2003103581A2 (en) | 2002-06-05 | 2003-12-18 | Genentech, Inc. | Compositions and methods for liver growth and liver protection |
US20060040386A1 (en) * | 2004-01-14 | 2006-02-23 | Suchitra Holgersson | Human hepatic progenitor cells and methods of use thereof |
US8070703B2 (en) * | 2004-03-10 | 2011-12-06 | Vision Quest Industries Incorporated | Electrically stimulating orthotic device and segmented liner |
MX2007000783A (es) | 2004-07-20 | 2007-04-09 | Genentech Inc | Inhibidores de proteina angiopoietina tipo 4, combinaciones y su uso. |
NZ561763A (en) | 2005-03-24 | 2009-02-28 | Thrombogenics Nv | Novel anti PLGF antibody |
JP2008537551A (ja) | 2005-03-31 | 2008-09-18 | カランド ファーマシューティカルズ, インコーポレイテッド | リボヌクレオチドレダクターゼサブユニット2の阻害剤およびその使用 |
EP1904095B1 (en) * | 2005-06-30 | 2013-05-29 | VIB, vzw | Treatment of liver cirrhosis and its complications |
JP5036727B2 (ja) | 2005-12-22 | 2012-09-26 | ジェネンテック, インコーポレイテッド | ヘパリン結合タンパク質の組み換え体産生 |
EP2015768A1 (en) * | 2006-03-27 | 2009-01-21 | Genentech, Inc. | Methods for treating kidney disorders |
US8685730B2 (en) * | 2006-05-02 | 2014-04-01 | Wisconsin Alumni Research Foundation | Methods and devices for differentiating pluripotent stem cells into cells of the pancreatic lineage |
CN101250498B (zh) * | 2008-04-07 | 2010-06-09 | 南通大学附属医院 | 用载肝细胞生长因子聚乳酸-o-羧甲基壳聚糖纳米粒子的肝细胞培养方法 |
CN102239178B (zh) | 2008-10-02 | 2017-06-23 | Vib研究所 | 抑制PlGF以治疗费城染色体阳性白血病 |
ES2788300T3 (es) * | 2010-11-09 | 2020-10-21 | Univ Cornell | Regeneración hepática |
PL2508207T3 (pl) * | 2011-03-31 | 2013-09-30 | Bioalliance Pharma | Nanocząsteczki zawierające chemioterapeutyczny lek przeciwnowotworowy |
WO2013033513A1 (en) | 2011-08-31 | 2013-03-07 | University Of Georgia Research Foundation, Inc. | Apoptosis-targeting nanoparticles |
WO2013079713A1 (en) | 2011-12-01 | 2013-06-06 | Thrombogenics Nv | Improving trabeculectomy outcome |
JP6356614B2 (ja) | 2012-02-17 | 2018-07-11 | ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド | 薬剤のミトコンドリア輸送のためのナノ粒子 |
US10398663B2 (en) | 2014-03-14 | 2019-09-03 | University Of Georgia Research Foundation, Inc. | Mitochondrial delivery of 3-bromopyruvate |
KR102461927B1 (ko) * | 2016-02-17 | 2022-10-31 | 차의과학대학교 산학협력단 | 이식용 줄기세포 및 이를 포함하는 혈관신생의 유도 또는 촉진을 위한 이식용 약학 조성물 |
CN114224893B (zh) * | 2022-01-25 | 2023-06-06 | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 喹唑啉衍生物在制备防治砷致肝损伤药物中的用途 |
Family Cites Families (27)
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US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
NZ201918A (en) | 1981-09-18 | 1987-04-30 | Genentech Inc | N-terminal methionyl analogues of bovine growth hormone |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
US4892538A (en) | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
US5217999A (en) | 1987-12-24 | 1993-06-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Styryl compounds which inhibit EGF receptor protein tyrosine kinase |
EP0526488B1 (en) | 1990-04-02 | 1994-11-30 | Pfizer Inc. | Benzylphosphonic acid tyrosine kinase inhibitors |
US5302606A (en) | 1990-04-16 | 1994-04-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase |
EP0586608A1 (en) | 1991-05-29 | 1994-03-16 | Pfizer Inc. | Tricyclic polyhydroxylic tyrosine kinase inhibitors |
US5227158A (en) | 1991-06-10 | 1993-07-13 | Genentech, Inc. | Method of stimulating hepatocyte proliferation by administration of hepatocyte growth factor and gamma-interferon |
GB9300059D0 (en) | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
WO1994003427A1 (en) | 1992-08-06 | 1994-02-17 | Warner-Lambert Company | 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties |
US6107046A (en) | 1992-10-09 | 2000-08-22 | Orion Corporation | Antibodies to Flt4, a receptor tyrosine kinase and uses thereof |
US5330992A (en) | 1992-10-23 | 1994-07-19 | Sterling Winthrop Inc. | 1-cyclopropyl-4-pyridyl-quinolinones |
GB9226855D0 (en) | 1992-12-23 | 1993-02-17 | Erba Carlo Spa | Vinylene-azaindole derivatives and process for their preparation |
US6020473A (en) | 1995-08-25 | 2000-02-01 | Genentech, Inc. | Nucleic acids encoding variants of vascular endothelial cell growth factor |
WO1997009427A1 (en) * | 1995-09-08 | 1997-03-13 | Genentech, Inc. | Vegf-related protein |
US6100071A (en) | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
WO2000063380A1 (en) | 1999-04-16 | 2000-10-26 | Genentech, Inc. | Vascular endothelial cell growth factor variants and uses thereof |
CA2373822A1 (en) * | 1999-05-20 | 2000-11-30 | Scios Inc. | Vascular endothelial growth factor variants |
US20020164310A1 (en) * | 2001-03-02 | 2002-11-07 | Mgvs Ltd. | Nucleic acid constructs, cells transformed therewith and methods utilizing same for inducing liver regeneration and alleviation of portal hypertension |
US6659223B2 (en) * | 2001-10-05 | 2003-12-09 | Collins & Aikman Products Co. | Sound attenuating material for use within vehicles and methods of making same |
WO2003103581A2 (en) | 2002-06-05 | 2003-12-18 | Genentech, Inc. | Compositions and methods for liver growth and liver protection |
-
2003
- 2003-06-05 WO PCT/US2003/017591 patent/WO2003103581A2/en active Application Filing
- 2003-06-05 US US10/455,470 patent/US7700571B2/en not_active Expired - Fee Related
- 2003-06-05 EP EP03757334.2A patent/EP1531676B1/en not_active Expired - Lifetime
- 2003-06-05 EP EP11180450A patent/EP2430923A1/en not_active Withdrawn
- 2003-06-05 AU AU2003251397A patent/AU2003251397B2/en not_active Ceased
- 2003-06-05 IL IL16539203A patent/IL165392A0/xx unknown
- 2003-06-05 JP JP2004510702A patent/JP5111729B2/ja not_active Expired - Fee Related
- 2003-06-05 CA CA2486270A patent/CA2486270C/en not_active Expired - Fee Related
-
2004
- 2004-11-25 IL IL165392A patent/IL165392A/en active IP Right Grant
-
2005
- 2005-10-31 HK HK05109684.7A patent/HK1076227A1/xx not_active IP Right Cessation
-
2006
- 2006-09-25 US US11/535,049 patent/US7709455B2/en not_active Expired - Fee Related
-
2010
- 2010-02-24 JP JP2010038622A patent/JP2010159266A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP2430923A1 (en) | 2012-03-21 |
JP2005534648A (ja) | 2005-11-17 |
EP1531676B1 (en) | 2015-07-22 |
WO2003103581A2 (en) | 2003-12-18 |
US7700571B2 (en) | 2010-04-20 |
JP2010159266A (ja) | 2010-07-22 |
EP1531676A2 (en) | 2005-05-25 |
CA2486270A1 (en) | 2003-12-18 |
AU2003251397A1 (en) | 2003-12-22 |
AU2003251397B2 (en) | 2009-10-01 |
JP5111729B2 (ja) | 2013-01-09 |
IL165392A (en) | 2015-11-30 |
US7709455B2 (en) | 2010-05-04 |
US20070122394A1 (en) | 2007-05-31 |
CA2486270C (en) | 2015-07-28 |
IL165392A0 (en) | 2006-01-15 |
WO2003103581A3 (en) | 2004-04-15 |
US20040170613A1 (en) | 2004-09-02 |
EP1531676A4 (en) | 2009-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190605 |