HK1057333A1 - Flavone-containing plant extract solutions having improved storage and heat stability - Google Patents

Flavone-containing plant extract solutions having improved storage and heat stability

Info

Publication number
HK1057333A1
HK1057333A1 HK03108336A HK03108336A HK1057333A1 HK 1057333 A1 HK1057333 A1 HK 1057333A1 HK 03108336 A HK03108336 A HK 03108336A HK 03108336 A HK03108336 A HK 03108336A HK 1057333 A1 HK1057333 A1 HK 1057333A1
Authority
HK
Hong Kong
Prior art keywords
plant extract
flavone
solutions
containing plant
component
Prior art date
Application number
HK03108336A
Inventor
Joachim Herrmann
Rainer Oschmann
Heinz Stumpf
Marc Thole
Original Assignee
Schwabe Willmar Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schwabe Willmar Gmbh & Co filed Critical Schwabe Willmar Gmbh & Co
Publication of HK1057333A1 publication Critical patent/HK1057333A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to flavone-containing plant extract solutions that are characterized by improved storage and heat stability with regard to their content in pharmaceutically relevant ingredients (especially flavones and/or terpenes). The inventive plant extract solutions contain the corresponding plant extracts in an aqueous alcohol solvent in an amount of from 2-40 % m/m alcohol in water. The pH of said solutions is in the acidic range of from pH 2 to pH 6. The solutions are used in the production of two-component medicaments, namely said flavone-containing plant extract solution as the component (A) and a sterile buffer salt solution that has a physiologically acceptable composition as the component (B). The two components (A) and (B) are mixed for administration but are produced separately and stored separately in separate containers until administered.
HK03108336A 2000-08-16 2003-11-14 Flavone-containing plant extract solutions having improved storage and heat stability HK1057333A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10040610A DE10040610A1 (en) 2000-08-16 2000-08-16 Flavonhaltige plant extract solutions with improved storage and heat stability
PCT/DE2001/002871 WO2002013869A2 (en) 2000-08-16 2001-07-24 Flavone-containing plant extract solutions having improved storage and heat stability

Publications (1)

Publication Number Publication Date
HK1057333A1 true HK1057333A1 (en) 2004-04-02

Family

ID=7653008

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03108336A HK1057333A1 (en) 2000-08-16 2003-11-14 Flavone-containing plant extract solutions having improved storage and heat stability

Country Status (8)

Country Link
EP (1) EP1309353B1 (en)
KR (1) KR20030020390A (en)
CN (1) CN1447698B (en)
AT (1) ATE305800T1 (en)
AU (1) AU2001281717A1 (en)
DE (2) DE10040610A1 (en)
HK (1) HK1057333A1 (en)
WO (1) WO2002013869A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020387478A1 (en) * 2019-11-22 2022-06-16 Samyang Holdings Corporation Kit for preparing nanoparticle composition for drug delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB820788A (en) * 1956-05-28 1959-09-23 Klinge Co Chem Pharm Fab Extracts of parts of plants of the genus aesculus
DE1182776B (en) * 1961-08-02 1964-12-03 Chemiewerk Homburg Zweignieder Process for increasing the solubility of theophylline
DE2117429C3 (en) * 1971-04-08 1982-04-01 Fa. Dr. Willmar Schwabe, 7500 Karlsruhe Process for the production of an injection or infusion preparation with a content of an active substance mixture from the leaves of Ginkgo biloba
DE4030758A1 (en) * 1990-09-28 1992-04-02 Schwabe Willmar Gmbh & Co EXTRACTS FROM BLACKERS OF GINKGO BILOBA, IN PARTICULAR FOR INTRAVENOESE INJECTION OR INFUSION, PROCESS FOR THE PRODUCTION THEREOF AND THE EXTRACT CONTAINING AMPOULE PREPARATIONS
CH686556A5 (en) * 1994-07-14 1996-04-30 Flachsmann Ag Emil Process for the preparation of pesticide-poor concentrates of active ingredient from plants.
DE19823679C2 (en) * 1998-05-20 2002-05-08 Nativia Health Products Gmbh I Use of Crataegus preparations for the prophylaxis and therapy of neoplastic diseases

Also Published As

Publication number Publication date
EP1309353A2 (en) 2003-05-14
DE10040610A1 (en) 2002-03-07
AU2001281717A1 (en) 2002-02-25
DE50107626D1 (en) 2006-02-16
WO2002013869A2 (en) 2002-02-21
EP1309353B1 (en) 2005-10-05
KR20030020390A (en) 2003-03-08
CN1447698B (en) 2012-02-29
ATE305800T1 (en) 2005-10-15
WO2002013869A3 (en) 2002-06-20
CN1447698A (en) 2003-10-08

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Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20210723