CN106420781A - Composition with anti-aging effect and application of composition - Google Patents
Composition with anti-aging effect and application of composition Download PDFInfo
- Publication number
- CN106420781A CN106420781A CN201611046133.8A CN201611046133A CN106420781A CN 106420781 A CN106420781 A CN 106420781A CN 201611046133 A CN201611046133 A CN 201611046133A CN 106420781 A CN106420781 A CN 106420781A
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- CN
- China
- Prior art keywords
- compositionss
- aging effects
- composition
- genistin
- puerarin
- Prior art date
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- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 34
- 239000000203 mixture Substances 0.000 title abstract description 13
- ZCOLJUOHXJRHDI-CMWLGVBASA-N genistein 7-O-beta-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 ZCOLJUOHXJRHDI-CMWLGVBASA-N 0.000 claims abstract description 29
- ZQSIJRDFPHDXIC-UHFFFAOYSA-N Daidzein Natural products C1=CC(O)=CC=C1C1=COC2=CC(O)=CC=C2C1=O ZQSIJRDFPHDXIC-UHFFFAOYSA-N 0.000 claims abstract description 18
- ZCOLJUOHXJRHDI-FZHKGVQDSA-N Genistein 7-O-glucoside Natural products O([C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1)c1cc(O)c2C(=O)C(c3ccc(O)cc3)=COc2c1 ZCOLJUOHXJRHDI-FZHKGVQDSA-N 0.000 claims abstract description 16
- CJPNHKPXZYYCME-UHFFFAOYSA-N Genistin Natural products OCC1OC(Oc2ccc(O)c3OC(=CC(=O)c23)c4ccc(O)cc4)C(O)C(O)C1O CJPNHKPXZYYCME-UHFFFAOYSA-N 0.000 claims abstract description 16
- YCUNGEJJOMKCGZ-UHFFFAOYSA-N Pallidiflorin Natural products C1=CC(OC)=CC=C1C1=COC2=CC=CC(O)=C2C1=O YCUNGEJJOMKCGZ-UHFFFAOYSA-N 0.000 claims abstract description 16
- RXUWDKBZZLIASQ-UHFFFAOYSA-N Puerarin Natural products OCC1OC(Oc2c(O)cc(O)c3C(=O)C(=COc23)c4ccc(O)cc4)C(O)C(O)C1O RXUWDKBZZLIASQ-UHFFFAOYSA-N 0.000 claims abstract description 15
- HKEAFJYKMMKDOR-VPRICQMDSA-N puerarin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=CC(C2=O)=C1OC=C2C1=CC=C(O)C=C1 HKEAFJYKMMKDOR-VPRICQMDSA-N 0.000 claims abstract description 15
- GMTUGPYJRUMVTC-UHFFFAOYSA-N Daidzin Natural products OC(COc1ccc2C(=O)C(=COc2c1)c3ccc(O)cc3)C(O)C(O)C(O)C=O GMTUGPYJRUMVTC-UHFFFAOYSA-N 0.000 claims abstract description 14
- KYQZWONCHDNPDP-UHFFFAOYSA-N Daidzoside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 KYQZWONCHDNPDP-UHFFFAOYSA-N 0.000 claims abstract description 14
- KYQZWONCHDNPDP-QNDFHXLGSA-N daidzein 7-O-beta-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 KYQZWONCHDNPDP-QNDFHXLGSA-N 0.000 claims abstract description 14
- TZBJGXHYKVUXJN-UHFFFAOYSA-N genistein Natural products C1=CC(O)=CC=C1C1=COC2=CC(O)=CC(O)=C2C1=O TZBJGXHYKVUXJN-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000006539 genistein Nutrition 0.000 claims abstract description 13
- 229940045109 genistein Drugs 0.000 claims abstract description 13
- -1 Daidezin Chemical compound 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 4
- 229910052791 calcium Inorganic materials 0.000 claims description 4
- 239000011575 calcium Substances 0.000 claims description 4
- 239000002537 cosmetic Substances 0.000 claims description 4
- 239000012190 activator Substances 0.000 claims description 2
- 239000003963 antioxidant agent Substances 0.000 claims description 2
- 230000003078 antioxidant effect Effects 0.000 claims description 2
- 235000006708 antioxidants Nutrition 0.000 claims description 2
- 235000013373 food additive Nutrition 0.000 claims description 2
- 239000002778 food additive Substances 0.000 claims description 2
- 239000004094 surface-active agent Substances 0.000 claims description 2
- 239000000080 wetting agent Substances 0.000 claims description 2
- 210000000481 breast Anatomy 0.000 abstract description 5
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract description 3
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract description 3
- 230000036541 health Effects 0.000 abstract description 3
- 230000009245 menopause Effects 0.000 abstract description 3
- 206010003210 Arteriosclerosis Diseases 0.000 abstract description 2
- 206010006242 Breast enlargement Diseases 0.000 abstract description 2
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract description 2
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract description 2
- 230000037303 wrinkles Effects 0.000 abstract description 2
- 235000007240 daidzein Nutrition 0.000 abstract 2
- 208000024891 symptom Diseases 0.000 abstract 2
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
- 230000000474 nursing effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 239000000546 pharmaceutical excipient Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 150000002576 ketones Chemical class 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- 229920001353 Dextrin Polymers 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 206010027304 Menopausal symptoms Diseases 0.000 description 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 2
- 241000122904 Mucuna Species 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000008108 microcrystalline cellulose Substances 0.000 description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 229940046011 buccal tablet Drugs 0.000 description 1
- 239000006189 buccal tablet Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000006184 cosolvent Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000003075 phytoestrogen Substances 0.000 description 1
- 229940023488 pill Drugs 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000012264 purified product Substances 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides composition with an anti-aging effect and an application of the composition. The composition contains daidzin, daidzein, genistin, genistein and puerarin in the weight ratio of daidzin to daidzein to genistin to genistein to puerarin being (3*10<4>-7*10<4>):(6-10):(0.8*10<4>-1.5*10<4>):(1-3):(80-110). The composition with the anti-aging effect can be used for health care of skin, breast nursing (including breast firmness, breast enlargement and removal of breast wrinkles) and treatment of prostatic hyperplasia, hypercholesterolemia, arteriosclerosis, erectile dysfunction, menopause symptoms and post-menopause symptoms.
Description
Technical field
The invention belongs to Medicines and Health Product field, is related to a kind of compositionss with anti-aging effects and its application.
Background technology
Radix Puerariae is the leguminous plant for being mainly distributed on Thailand, and mucuna is mainly distributed on the tall and big of subtropical area
Leguminous plant.25 or more compound is found in these plants, including genistin, genistein, cupreol,
Long-chain alcohol.Particularly, these plants are found containing phytoestrogen.However, how to realize these compounds each other
Coordinate, more preferable effect is realized, is still needed and want scientific research personnel to be continuing effort to.
Content of the invention
The present invention provides a kind of compositionss with anti-aging effects to overcome at least one deficiency of prior art,
To realize lower elasticity and the gloss that can increase skin of here combination, and treatment prostatic hyperplasia, hypercholesterolemia, tremulous pulse is hard
Change, the purpose in erection disturbance and menopause, postmenopausal symptom.
To achieve these goals, the present invention is employed the following technical solutions：
Compositionss with anti-aging effects, it is characterised in that the compositionss with anti-aging effects include Semen Glyciness
Glycosides, Daidezin, genistin, genistein and puerarin, wherein daidzin, Daidezin, genistin, dyewood Huang
The weight ratio of ketone and puerarin is (3*104-7*104)：(6-10)：(0.8*104-1.5*104)：(1-3)：(80-110).
Further, daidzin in the compositionss with anti-aging effects, Daidezin, genistin, dyewood Huang
The weight ratio of ketone and puerarin is (4*104-6*104)：(7-9)：(1*104-1.3*104)：(1.2-2.5)：(90-100).
Further, daidzin in the compositionss with anti-aging effects, Daidezin, genistin, dyewood Huang
The weight ratio of ketone and puerarin is 5.1*104：8.1：1.2*104：2：96.
Further, the compositionss with anti-aging effects are also comprising inorganic calcium or organic calcium.
Further, the compositionss with anti-aging effects also include activator, surfactant, wetting agent, antioxygen
One or more in agent, the compositionss can also also include excipient.Excipient of the present invention, the excipient
It is to refer to increase stability, pH value, permeability, bioavailability and transparency of invention formulation etc. and do not produce secondary work
With, the additional material in addition to principal agent that do not affect the treatment, including but not limited to binding agent, filler, disintegrating agent, lubricant, anti-
Rotten agent, antioxidant, correctivess, aromatic, cosolvent, emulsifying agent, solubilizing agent, osmotic pressure regulator, coloring agent etc..
The present invention also provides application of the above-mentioned compositionss with anti-aging effects as food additive.
The present invention also provides the above-mentioned compositionss with anti-aging effects and is preparing the application in cosmetics.
The present invention also provides the above-mentioned compositionss with anti-aging effects and is preparing the application in medicine.
The compositionss with anti-aging effects of the present invention are when medicine is prepared into, and the medicine has anti-aging effects
Compositionss are can be made into suitable for various pharmaceutical dosage forms such as oral administration, intravenous injection administration sublingual administrations.Specifically used form bag
Tablet, granule, pill, capsule, buccal tablet, aqueous suspension or oil suspending agent, tincture is included, dispersibled powder, solution, Emulsion, hang
Floating agent and other suitable forms.
Available carrier includes glucose, Lactose, dextrin, Microcrystalline Cellulose, arabic gum, gelatin, mannitol, starch
Paste, magnesium stearate, Talcum, silica gel and other carriers suitable for producing preparation with solid, semi-solid or liquid form.Separately
Auxiliary reagent, stabilizer, thickening agent can be used outward, can also be come from one or more flavoring agent, coloring agent, antistaling agent etc.
The pharmaceutical preparation of good palatability is provided.Preferably, Microcrystalline Cellulose, dextrin, Lactose, magnesium stearate are selected as excipient substance.
Compared with prior art, the present invention has advantages below：
The compositionss of the present invention can increase elasticity and the gloss of skin in the application in human body.Additionally, compositionss are available
In skin care, breast-nursing (, breast enlargement firm including breast removes breast wrinkle) and treatment prostatic hyperplasia, high gallbladder is solid
Alcoholemia, arteriosclerosis, erection disturbance and menopause, postmenopausal symptom.For manufacturing cosmetics, cosmeceutical,
Pharmaceutically useful product and health product, functional food, beverage.
It is that above and other objects of the present invention, feature and advantage can be become apparent, preferred embodiment cited below particularly,
It is described in detail below.
Specific embodiment
Embodiment 1
The weight ratio of daidzin, Daidezin, genistin, genistein and puerarin is 3*104：6：0.8*104：
1：80.
Composition wherein in above-mentioned composition is the material that extract in Radix Puerariae and/or mucuna, commercially available,
The purified product for corresponding product is sought, its purity requirement is more than 99%.
Embodiment 2
Compositionss with anti-aging effects, its composition includes：
The weight ratio of daidzin, Daidezin, genistin, genistein and puerarin is 4*104：7：1*104：
1.2：90.
Embodiment 3
Compositionss with anti-aging effects, its composition includes：
The weight ratio of daidzin, Daidezin, genistin, genistein and puerarin is 5.1*104：8.1：1.2*
104：2：96.
Embodiment 4
Compositionss with anti-aging effects, its composition includes：
The weight ratio of daidzin, Daidezin, genistin, genistein and puerarin is 6*104：9：1.3*104：
2.5：100.
Embodiment 5
Compositionss with anti-aging effects, its composition includes：
The weight ratio of daidzin, Daidezin, genistin, genistein and puerarin is 7*104：10：1.5*104：
3：110.
The above is the preferred embodiment of the present invention, it is noted that for the those of ordinary skill of this technology neighborhood
For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as
Protection scope of the present invention.
Claims (8)
1. compositionss with anti-aging effects, it is characterised in that the compositionss with anti-aging effects include daidzin,
Daidezin, genistin, genistein and puerarin, wherein daidzin, Daidezin, genistin, genistein
Weight ratio with puerarin is (3*104-7*104)：(6-10)：(0.8*104-1.5*104)：(1-3)：(80-110).
2. compositionss with anti-aging effects according to claim 1, it is characterised in that described with anti-aging effects
Compositionss in daidzin, Daidezin, genistin, the weight ratio of genistein and puerarin be4-6*104)：
(7-9)：(1*104-1.3*104)：(1.2-2.5)：(90-100).
3. compositionss with anti-aging effects according to claim 1, it is characterised in that described with anti-aging effects
Compositionss in daidzin, Daidezin, genistin, the weight ratio of genistein and puerarin be4：8.1：
1.2*104：2：96.
4. compositionss with anti-aging effects according to claim 1, it is characterised in that described with anti-aging effects
Compositionss also comprising inorganic calcium or organic calcium.
5. compositionss with anti-aging effects according to claim 1, it is characterised in that described with anti-aging effects
Compositionss also include activator, surfactant, wetting agent, one or more in antioxidant.
6. the compositionss with anti-aging effects as described in claim 1-3 any one are used as the application of food additive.
7. the compositionss with anti-aging effects as described in claim 1-3 any one are preparing the application in cosmetics.
8. the compositionss with anti-aging effects as described in claim 1-3 any one are preparing the application in medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611046133.8A CN106420781A (en) | 2016-11-22 | 2016-11-22 | Composition with anti-aging effect and application of composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611046133.8A CN106420781A (en) | 2016-11-22 | 2016-11-22 | Composition with anti-aging effect and application of composition |
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| Publication Number | Publication Date |
|---|---|
| CN106420781A true CN106420781A (en) | 2017-02-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201611046133.8A Pending CN106420781A (en) | 2016-11-22 | 2016-11-22 | Composition with anti-aging effect and application of composition |
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| Country | Link |
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| CN (1) | CN106420781A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112190616A (en) * | 2019-07-08 | 2021-01-08 | 大江生医股份有限公司 | Plant fermentation product and application thereof |
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| WO2001015718A1 (en) * | 1999-08-27 | 2001-03-08 | Cheil Jedang Corporation | Extracts derived from pueraria mirifica, butea superba and/or mucuna collettii and extraction thereof |
| CN103110687A (en) * | 2011-11-17 | 2013-05-22 | 胡晓娟 | Compound effervescent preparation containing soy isoflavone |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001015718A1 (en) * | 1999-08-27 | 2001-03-08 | Cheil Jedang Corporation | Extracts derived from pueraria mirifica, butea superba and/or mucuna collettii and extraction thereof |
| CN103110687A (en) * | 2011-11-17 | 2013-05-22 | 胡晓娟 | Compound effervescent preparation containing soy isoflavone |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112190616A (en) * | 2019-07-08 | 2021-01-08 | 大江生医股份有限公司 | Plant fermentation product and application thereof |
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