HK1054570A1 - 克隆培養肝祖先細胞的方法 - Google Patents

克隆培養肝祖先細胞的方法 Download PDF

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Publication number
HK1054570A1
HK1054570A1 HK03106718.5A HK03106718A HK1054570A1 HK 1054570 A1 HK1054570 A1 HK 1054570A1 HK 03106718 A HK03106718 A HK 03106718A HK 1054570 A1 HK1054570 A1 HK 1054570A1
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progenitors
culture medium
mammalian
differentiation
growth
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HK03106718.5A
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Chinese (zh)
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Kubota Hiroshi
M. Reid Lola
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University Of North Carolina
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK03106718.5A 2000-10-03 2000-10-03 克隆培養肝祖先細胞的方法 HK1054570A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/027428 WO2002029012A1 (en) 2000-10-03 2000-10-03 Processes for clonal growth of hepatic progenitor cells

Publications (1)

Publication Number Publication Date
HK1054570A1 true HK1054570A1 (zh) 2003-12-05

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ID=21741846

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Application Number Title Priority Date Filing Date
HK03106718.5A HK1054570A1 (zh) 2000-10-03 2000-10-03 克隆培養肝祖先細胞的方法

Country Status (9)

Country Link
EP (1) EP1325111A1 (cg-RX-API-DMAC7.html)
JP (1) JP2004510434A (cg-RX-API-DMAC7.html)
KR (1) KR100887623B1 (cg-RX-API-DMAC7.html)
CN (1) CN1461341A (cg-RX-API-DMAC7.html)
AU (2) AU2000277535B2 (cg-RX-API-DMAC7.html)
CA (1) CA2424779C (cg-RX-API-DMAC7.html)
HK (1) HK1054570A1 (cg-RX-API-DMAC7.html)
IL (1) IL155387A0 (cg-RX-API-DMAC7.html)
WO (1) WO2002029012A1 (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL142094A0 (en) 1998-09-29 2002-03-10 Gamida Cell Ltd Methods of controlling proliferation and differentiation of stem and progenitor cells
US20020187133A1 (en) 1999-10-01 2002-12-12 Hiroshi Kubota Methods of isolating bipotent hepatic progenitor cells
ATE431396T1 (de) 2001-03-27 2009-05-15 Vertex Pharma Für hcv-infektion geeignete zusammensetzungen und verfahren
IL152904A0 (en) * 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
HUE032238T2 (en) * 2002-03-15 2017-09-28 Univ North Carolina Chapel Hill Primitive and proximal liver stem cells
US7763466B2 (en) * 2002-05-17 2010-07-27 Mount Sinai School Of Medicine Of New York University Mesoderm and definitive endoderm cell populations
US20060003446A1 (en) 2002-05-17 2006-01-05 Gordon Keller Mesoderm and definitive endoderm cell populations
US8669109B2 (en) 2003-08-19 2014-03-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Methods of producing proteins in Chinese hamster ovary (CHO) cells
DE10338531A1 (de) * 2003-08-19 2005-04-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Reklonierung von Produktionszellen
US7332336B2 (en) 2003-08-19 2008-02-19 Effector Cell Institute, Inc. Methods for inducing differentiation of pluripotent cells
AU2005205240B2 (en) * 2004-01-14 2011-04-21 Novahep Ab Human hepatic progenitor cells and methods of use thereof
KR20060114381A (ko) * 2004-02-13 2006-11-06 레프로셀 인코퍼레이티드 배아줄기세포용 피더세포 작성 배지 및 피더세포
US8874380B2 (en) 2010-12-09 2014-10-28 Rutgers, The State University Of New Jersey Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs
WO2008056368A2 (en) * 2006-11-09 2008-05-15 Gamida-Cell Ltd. Use of ex-vivo cultured hematopoietic cells for treatment of peripheral vascular diseases
CN101275121B (zh) * 2007-03-26 2011-05-11 芦银雪 体外培养扩增的人肝脏祖先细胞及其制备方法
CA2693481A1 (en) * 2007-07-20 2009-01-29 Cellartis Ab A novel population of hepatocytes derived via definitive endoderm (de-hep) from human blastocysts derived stem cells
CN101701219B (zh) * 2009-11-06 2013-02-20 哈尔滨医科大学 编码兔肝细胞生长因子的cDNA及其表达载体和应用
JP6232638B2 (ja) * 2013-06-24 2017-11-22 国立研究開発法人医薬基盤・健康・栄養研究所 肝前駆細胞増殖用培地
CN104630130A (zh) * 2014-12-05 2015-05-20 新乡医学院 一种大鼠肝细胞分离方法
CN120642821B (zh) * 2025-06-20 2026-05-19 北京医院 一种协同延长中性粒细胞体外存活时间的培养方法及组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4914032A (en) * 1985-06-06 1990-04-03 Centro De Investigation Y Estudios Avanzados Del Instituto Politecnico Nacional Process for the long-term surviving culture of hepatocytes
CA2115140A1 (en) * 1991-08-07 1993-02-18 Lola M. Reid Proliferation of hepatocyte precursors
CA2177043C (en) * 1993-11-19 2011-08-09 Lola C.M. Reid Hepatoblasts and method of isolating same
CA2146735C (en) * 1994-04-11 2007-02-20 Chise Tateno Liver parenchymal cells having clonal growth ability, method for obtaining same, method for subculturing same, and subculturing system of primary hepatocytes
JP3266766B2 (ja) * 1994-08-23 2002-03-18 科学技術振興事業団 ローン性増殖能を有する肝実質細胞とその取得方法、並びにその継代培養方法
CA2877233A1 (en) * 1999-01-19 2000-07-27 Lola M. Reid Human liver progenitors
JP2004510432A (ja) * 2000-10-03 2004-04-08 ユニバーシティ オブ ノース カロライナ 両能性肝前駆細胞の単離方法

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Publication number Publication date
JP2004510434A (ja) 2004-04-08
CA2424779C (en) 2016-08-23
CA2424779A1 (en) 2002-04-11
EP1325111A1 (en) 2003-07-09
CN1461341A (zh) 2003-12-10
AU2000277535B2 (en) 2007-03-29
KR100887623B1 (ko) 2009-03-11
KR20040047732A (ko) 2004-06-05
IL155387A0 (en) 2003-11-23
AU7753500A (en) 2002-04-15
WO2002029012A1 (en) 2002-04-11

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