HK1046373A1 - 用作抗腫瘤劑的二硫雜環戊烯並吡咯酮及其相應的一氧化物和二氧化物 - Google Patents

用作抗腫瘤劑的二硫雜環戊烯並吡咯酮及其相應的一氧化物和二氧化物

Info

Publication number
HK1046373A1
HK1046373A1 HK02107990.3A HK02107990A HK1046373A1 HK 1046373 A1 HK1046373 A1 HK 1046373A1 HK 02107990 A HK02107990 A HK 02107990A HK 1046373 A1 HK1046373 A1 HK 1046373A1
Authority
HK
Hong Kong
Prior art keywords
dithiolopyrrolones
monoxides
dioxides
antineoplastic
corresponding monoxides
Prior art date
Application number
HK02107990.3A
Other languages
English (en)
Inventor
約翰‧麥爾康姆‧韋伯斯特
李建雄
Original Assignee
約翰‧麥爾康姆‧韋伯斯特
李建雄
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 約翰‧麥爾康姆‧韋伯斯特, 李建雄 filed Critical 約翰‧麥爾康姆‧韋伯斯特
Publication of HK1046373A1 publication Critical patent/HK1046373A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK02107990.3A 1997-09-05 2002-11-02 用作抗腫瘤劑的二硫雜環戊烯並吡咯酮及其相應的一氧化物和二氧化物 HK1046373A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002212237A CA2212237A1 (en) 1997-09-05 1997-09-05 Novel antineoplastic agents

Publications (1)

Publication Number Publication Date
HK1046373A1 true HK1046373A1 (zh) 2003-01-10

Family

ID=4161181

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02107990.3A HK1046373A1 (zh) 1997-09-05 2002-11-02 用作抗腫瘤劑的二硫雜環戊烯並吡咯酮及其相應的一氧化物和二氧化物

Country Status (7)

Country Link
EP (1) EP1009401A1 (zh)
JP (1) JP2001515861A (zh)
CN (2) CN1276723A (zh)
AU (1) AU759990B2 (zh)
CA (1) CA2212237A1 (zh)
HK (1) HK1046373A1 (zh)
WO (1) WO1999012543A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1238668A1 (en) * 2001-03-09 2002-09-11 Aventis Pharma Deutschland GmbH Use of thiolutin dioxide and its derivatives in the manufacture of a medicament for the treatment of CNS disorders and a process for the preparation thereof
US9051330B2 (en) 2002-03-26 2015-06-09 Welichem Biotech Inc. Dithiolopyrrolones with therapeutic activity
CN101522688B (zh) 2006-09-29 2011-09-14 北京文丰天济医药科技有限公司 二硫杂环戊烯并吡咯酮类新化合物及其治疗性应用
CN101381371B (zh) 2007-09-05 2011-05-18 上海医药工业研究院 二硫杂环戊烯并吡咯酮类化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1214130A (en) * 1982-10-26 1986-11-18 Stuart H. Rhodes Xenorhabdin antibiotics
DE19513040A1 (de) * 1995-03-29 1996-10-02 Schering Ag Neue Borneolester, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
AU752376B2 (en) * 1995-04-11 2002-09-19 Welichem Biotech Inc. Xenorxides with antibacterial and antimycotic properties

Also Published As

Publication number Publication date
CN1360891A (zh) 2002-07-31
WO1999012543A1 (en) 1999-03-18
CN1276723A (zh) 2000-12-13
JP2001515861A (ja) 2001-09-25
AU9057098A (en) 1999-03-29
EP1009401A1 (en) 2000-06-21
AU759990B2 (en) 2003-05-01
CA2212237A1 (en) 1999-03-05

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