HK1045178B - 用於探測標記目標的單分子層和電極以及使用它們的方法 - Google Patents

用於探測標記目標的單分子層和電極以及使用它們的方法

Info

Publication number
HK1045178B
HK1045178B HK02106722.0A HK02106722A HK1045178B HK 1045178 B HK1045178 B HK 1045178B HK 02106722 A HK02106722 A HK 02106722A HK 1045178 B HK1045178 B HK 1045178B
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
electrode
oxidation
detecting
reduction reaction
Prior art date
Application number
HK02106722.0A
Other languages
English (en)
Other versions
HK1045178A1 (en
Inventor
Allen E Eckhardt
Jill C Mikulecky
Mary E Napier
Robert S Thomas
H Holden Thorp
Original Assignee
Univ North Carolina Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina Chapel Hill filed Critical Univ North Carolina Chapel Hill
Publication of HK1045178A1 publication Critical patent/HK1045178A1/xx
Publication of HK1045178B publication Critical patent/HK1045178B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
HK02106722.0A 1999-04-22 2002-09-13 用於探測標記目標的單分子層和電極以及使用它們的方法 HK1045178B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/296,929 US6127127A (en) 1995-06-27 1999-04-22 Monolayer and electrode for detecting a label-bearing target and method of use thereof
PCT/US2000/002976 WO2000065099A1 (en) 1999-04-22 2000-02-04 Monolayer and electrode for detecting a label-bearing target and method of use thereof

Publications (2)

Publication Number Publication Date
HK1045178A1 HK1045178A1 (en) 2002-11-15
HK1045178B true HK1045178B (zh) 2006-08-11

Family

ID=23144136

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02106722.0A HK1045178B (zh) 1999-04-22 2002-09-13 用於探測標記目標的單分子層和電極以及使用它們的方法

Country Status (13)

Country Link
US (1) US6127127A (zh)
EP (1) EP1185692B1 (zh)
JP (1) JP2002542794A (zh)
KR (1) KR20020008157A (zh)
CN (1) CN1347460A (zh)
AT (1) ATE312200T1 (zh)
AU (1) AU781085B2 (zh)
CA (1) CA2367594A1 (zh)
DE (1) DE60024618D1 (zh)
HK (1) HK1045178B (zh)
NO (1) NO20014882L (zh)
NZ (1) NZ514682A (zh)
WO (1) WO2000065099A1 (zh)

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Also Published As

Publication number Publication date
NO20014882D0 (no) 2001-10-08
WO2000065099A1 (en) 2000-11-02
KR20020008157A (ko) 2002-01-29
CN1347460A (zh) 2002-05-01
NZ514682A (en) 2003-07-25
HK1045178A1 (en) 2002-11-15
CA2367594A1 (en) 2000-11-02
ATE312200T1 (de) 2005-12-15
EP1185692B1 (en) 2005-12-07
NO20014882L (no) 2001-12-27
AU781085B2 (en) 2005-05-05
JP2002542794A (ja) 2002-12-17
AU3483000A (en) 2000-11-10
US6127127A (en) 2000-10-03
EP1185692A1 (en) 2002-03-13
DE60024618D1 (de) 2006-01-12

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100204