HK1044111B - 使用temozolomide的改良癌症治療 - Google Patents

使用temozolomide的改良癌症治療

Info

Publication number
HK1044111B
HK1044111B HK02103318.7A HK02103318A HK1044111B HK 1044111 B HK1044111 B HK 1044111B HK 02103318 A HK02103318 A HK 02103318A HK 1044111 B HK1044111 B HK 1044111B
Authority
HK
Hong Kong
Prior art keywords
temozolomide
cancer treatment
improved cancer
improved
treatment
Prior art date
Application number
HK02103318.7A
Other languages
English (en)
Other versions
HK1044111A1 (en
Inventor
H Ragab Mohamed
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of HK1044111A1 publication Critical patent/HK1044111A1/xx
Publication of HK1044111B publication Critical patent/HK1044111B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK02103318.7A 1999-03-30 2002-05-02 使用temozolomide的改良癌症治療 HK1044111B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28134899A 1999-03-30 1999-03-30
PCT/US2000/008079 WO2000057867A2 (en) 1999-03-30 2000-03-27 Improved cancer treatment with temozolomide

Publications (2)

Publication Number Publication Date
HK1044111A1 HK1044111A1 (en) 2002-10-11
HK1044111B true HK1044111B (zh) 2006-02-24

Family

ID=23076905

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02103318.7A HK1044111B (zh) 1999-03-30 2002-05-02 使用temozolomide的改良癌症治療

Country Status (18)

Country Link
EP (1) EP1165071B1 (zh)
JP (2) JP2002540148A (zh)
CN (2) CN102160864A (zh)
AR (1) AR023185A1 (zh)
AT (1) ATE310515T1 (zh)
AU (1) AU780892B2 (zh)
BR (1) BR0009380A (zh)
CA (1) CA2368614C (zh)
DE (1) DE60024243T2 (zh)
DK (1) DK1165071T3 (zh)
ES (1) ES2251987T3 (zh)
HK (1) HK1044111B (zh)
HU (1) HUP0200805A3 (zh)
NO (1) NO330651B1 (zh)
NZ (1) NZ536302A (zh)
TW (1) TWI276434B (zh)
WO (1) WO2000057867A2 (zh)
ZA (1) ZA200107736B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366249C (zh) * 2002-09-29 2008-02-06 天津帝士力投资控股集团有限公司 一种替莫唑胺控释给药系统
CN1742723A (zh) * 2004-09-02 2006-03-08 天津倍方科技发展有限公司 含有替莫唑胺－8－羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途
CN1299772C (zh) * 2004-10-14 2007-02-14 孔庆忠 一种抗癌药物组合物
CN101098696A (zh) * 2004-11-09 2008-01-02 先灵公司 基于患者mgmt水平来治疗癌症的替莫唑胺的改进给药方案
EP1976515A2 (en) * 2006-01-17 2008-10-08 Abbott Laboratories Combination therapy with parp inhibitors
CL2007000945A1 (es) * 2006-04-05 2008-01-25 Schering Corp Formulacion farmaceutica que comprende una sal cristalina de monohidrato de hidrocloruro de (5s,8s)-8-[[(1r)-1-(3,5-bistrifluorometil)fenil]-etoximetil]-8-fenil-1,7-diaza-espiro[4.5]decan-2-ona; capsula que la contiene; y uso en el tratamiento de la emesis y nausea.
AR061618A1 (es) * 2006-06-26 2008-09-10 Schering Corp Formas de dosificacion unitaria de temozolomida
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
NZ575636A (en) * 2006-09-29 2012-02-24 Cipla Ltd An improved process for the preparation of temozolomide and analogs
WO2012075210A2 (en) * 2010-12-01 2012-06-07 Niiki Pharma Inc. Method for treating refractory cancer
CN102526038B (zh) * 2011-01-12 2013-09-11 北京人福军威医药技术开发有限公司 替莫唑胺的脑靶向药物组合物及其应用
CN107397735B (zh) * 2017-07-28 2020-07-10 东曜药业有限公司 一种替莫唑胺药物组合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4156028B2 (ja) * 1995-10-04 2008-09-24 シェーリング コーポレイション 進行癌の処置のためのテモゾロミドとα−ＩＦＮの組合せ
CA2184545A1 (en) * 1996-07-31 1998-02-01 Pascale Reidenberg Cancer treatment with temozolomide
CA2184546A1 (en) * 1996-07-31 1998-02-01 Margaret H. Dugan Method for treating pediatric high grade astrocytoma including brain stem glioma

Also Published As

Publication number Publication date
NO20014725D0 (no) 2001-09-28
DK1165071T3 (da) 2006-02-20
AU780892B2 (en) 2005-04-21
AR023185A1 (es) 2002-09-04
WO2000057867A2 (en) 2000-10-05
NO330651B1 (no) 2011-05-30
ES2251987T3 (es) 2006-05-16
CN1345240A (zh) 2002-04-17
AU3924400A (en) 2000-10-16
EP1165071B1 (en) 2005-11-23
CA2368614A1 (en) 2000-10-05
HUP0200805A2 (hu) 2002-07-29
ZA200107736B (en) 2003-02-26
HUP0200805A3 (en) 2004-07-28
EP1165071A2 (en) 2002-01-02
NZ536302A (en) 2006-05-26
ATE310515T1 (de) 2005-12-15
JP2002540148A (ja) 2002-11-26
TWI276434B (en) 2007-03-21
DE60024243D1 (de) 2005-12-29
CN102160864A (zh) 2011-08-24
JP2007169297A (ja) 2007-07-05
HK1044111A1 (en) 2002-10-11
WO2000057867A3 (en) 2001-04-19
CA2368614C (en) 2008-07-22
DE60024243T2 (de) 2006-08-17
NO20014725L (no) 2001-11-13
BR0009380A (pt) 2001-12-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150327