HK1039279A1 - 預測和治療腎病及相關疾病的基因和蛋白質 - Google Patents

預測和治療腎病及相關疾病的基因和蛋白質

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Publication number
HK1039279A1
HK1039279A1 HK02100827.7A HK02100827A HK1039279A1 HK 1039279 A1 HK1039279 A1 HK 1039279A1 HK 02100827 A HK02100827 A HK 02100827A HK 1039279 A1 HK1039279 A1 HK 1039279A1
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HK
Hong Kong
Prior art keywords
genes
differentially
rat
therapeutic
expressed
Prior art date
Application number
HK02100827.7A
Other languages
English (en)
Inventor
A Shimkets Richard
Original Assignee
Curagen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Curagen Corp filed Critical Curagen Corp
Publication of HK1039279A1 publication Critical patent/HK1039279A1/zh

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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • A—HUMAN NECESSITIES
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1748—Keratin; Cytokeratin
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1777—Integrin superfamily
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
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    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4853—Kallikrein (3.4.21.34 or 3.4.21.35)
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    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/11—Aminopeptidases (3.4.11)
    • C12Y304/11002—Membrane alanyl aminopeptidase (3.4.11.2), i.e. aminopeptidase N
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
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HK02100827.7A 1998-10-22 2002-02-02 預測和治療腎病及相關疾病的基因和蛋白質 HK1039279A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17726498A 1998-10-22 1998-10-22
PCT/US1999/024723 WO2000023100A2 (en) 1998-10-22 1999-10-22 Genes and proteins predictive and therapeutic for renal disease and associated disorders

Publications (1)

Publication Number Publication Date
HK1039279A1 true HK1039279A1 (zh) 2002-04-19

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ID=22647902

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Application Number Title Priority Date Filing Date
HK02100827.7A HK1039279A1 (zh) 1998-10-22 2002-02-02 預測和治療腎病及相關疾病的基因和蛋白質

Country Status (8)

Country Link
EP (1) EP1124572B1 (zh)
JP (1) JP2002527489A (zh)
AT (1) ATE249236T1 (zh)
AU (1) AU1449500A (zh)
CA (1) CA2347625A1 (zh)
DE (1) DE69911226D1 (zh)
HK (1) HK1039279A1 (zh)
WO (1) WO2000023100A2 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040146516A1 (en) * 1999-06-17 2004-07-29 Utah Ventures Ii L.P. Lumen-exposed molecules and methods for targeted delivery
AU2003224062A1 (en) * 2002-04-10 2003-10-20 Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung Proteins involved in the regulation of energy homeostasis
WO2005026736A2 (en) * 2003-09-13 2005-03-24 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with organic cation transporter slc22a2 (slc22a2)
WO2006008002A2 (en) * 2004-07-23 2006-01-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 1 (klk1)
US7329737B2 (en) 2004-08-03 2008-02-12 Dyax Corp. Antibodies that bind hK-1
BRPI0502497A (pt) * 2005-06-28 2007-02-06 Univ Minas Gerais uso de agonistas e antagonistas do receptor acoplado a proteìna g, mas, como moduladores de atividade apoptótica para o estudo, a prevenção e o tratamento de doenças
FR2938335A1 (fr) * 2008-11-13 2010-05-14 Galderma Res & Dev Modulateurs de l'isovaleryl-coenzyme a dehydrogenase dans le traitement de l'acne, d'une dermatite seborrheique ou de l'hyperseborrhee
EP2505661A1 (en) * 2011-03-28 2012-10-03 Universitätsklinikum Hamburg-Eppendorf Methods for detecting the mortality risk
WO2012174359A1 (en) * 2011-06-17 2012-12-20 The Johns Hopkins University Methods for increasing insulin sensitivity and treating diabetes
BR112014032728A2 (pt) 2012-06-27 2017-11-28 Berg Llc uso de marcadores no diagnóstico e tratamento de câncer de próstata
SG11201704660YA (en) 2014-12-08 2017-07-28 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
CN108271422A (zh) 2015-06-25 2018-07-10 株式会社国际电气通信基础技术研究所 基于器官间串扰系统的预测装置及预测程序
WO2017170803A1 (ja) 2016-03-29 2017-10-05 株式会社国際電気通信基礎技術研究所 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法
EP4005598A1 (en) * 2016-03-29 2022-06-01 Karydo Therapeutix, Inc. Screening method for candidate substances for active component to prevent or treat at least one disease selected from the group consisting of renal hypofunction, chronic kidney disease and kidney failure

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
DK0680333T3 (da) * 1993-01-21 2000-01-03 Erna Miller Forebyggelse og behandling af cytomegalovirus ved hjælp af aminopeptidase

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WO2000023100A8 (en) 2001-02-22
CA2347625A1 (en) 2000-04-27
WO2000023100A9 (en) 2000-08-24
WO2000023100A2 (en) 2000-04-27
JP2002527489A (ja) 2002-08-27
DE69911226D1 (de) 2003-10-16
EP1124572A2 (en) 2001-08-22
AU1449500A (en) 2000-05-08
WO2000023100A3 (en) 2000-11-23
EP1124572B1 (en) 2003-09-10
ATE249236T1 (de) 2003-09-15

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