WO2001059113A3 - G-protein coupled receptor proteins and nucleic acids encoding same - Google Patents

G-protein coupled receptor proteins and nucleic acids encoding same Download PDF

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Publication number
WO2001059113A3
WO2001059113A3 PCT/US2001/004404 US0104404W WO0159113A3 WO 2001059113 A3 WO2001059113 A3 WO 2001059113A3 US 0104404 W US0104404 W US 0104404W WO 0159113 A3 WO0159113 A3 WO 0159113A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
acids encoding
coupled receptor
protein coupled
receptor proteins
Prior art date
Application number
PCT/US2001/004404
Other languages
French (fr)
Other versions
WO2001059113A2 (en
Inventor
Raymond J Taupier Jr
Catherine E Burgess
Muralidhara Padigaru
Velizar T Tchernev
Vishnu S Mishra
Stacie Casman
Robert Ballinger
Corine A M Vernet
Li Li
Kimberly A Spytek
David P Andrew
Peter S Mezes
Original Assignee
Curagen Corp
Raymond J Taupier Jr
Catherine E Burgess
Muralidhara Padigaru
Velizar T Tchernev
Vishnu S Mishra
Stacie Casman
Robert Ballinger
Corine A M Vernet
Li Li
Kimberly A Spytek
David P Andrew
Peter S Mezes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Raymond J Taupier Jr, Catherine E Burgess, Muralidhara Padigaru, Velizar T Tchernev, Vishnu S Mishra, Stacie Casman, Robert Ballinger, Corine A M Vernet, Li Li, Kimberly A Spytek, David P Andrew, Peter S Mezes filed Critical Curagen Corp
Priority to AU2001239756A priority Critical patent/AU2001239756A1/en
Publication of WO2001059113A2 publication Critical patent/WO2001059113A2/en
Publication of WO2001059113A3 publication Critical patent/WO2001059113A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involding any one of these novel human nucleic acids and proteins.
PCT/US2001/004404 2000-02-08 2001-02-08 G-protein coupled receptor proteins and nucleic acids encoding same WO2001059113A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001239756A AU2001239756A1 (en) 2000-02-08 2001-02-08 Novel proteins and nucleic acids encoding same

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
US18092900P 2000-02-08 2000-02-08
US18104500P 2000-02-08 2000-02-08
US60/180,929 2000-02-08
US60/181,045 2000-02-08
US18134400P 2000-02-09 2000-02-09
US18133900P 2000-02-09 2000-02-09
US18115700P 2000-02-09 2000-02-09
US18139200P 2000-02-09 2000-02-09
US60/181,339 2000-02-09
US60/181,344 2000-02-09
US60/181,157 2000-02-09
US60/183,392 2000-02-09
US18319100P 2000-02-17 2000-02-17
US60/183,191 2000-02-17
US21958500P 2000-07-20 2000-07-20
US21975800P 2000-07-20 2000-07-20
US60/219,585 2000-07-20
US60/219,758 2000-07-20
US22134100P 2000-07-26 2000-07-26
US60/221,341 2000-07-26

Publications (2)

Publication Number Publication Date
WO2001059113A2 WO2001059113A2 (en) 2001-08-16
WO2001059113A3 true WO2001059113A3 (en) 2002-04-04

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/004404 WO2001059113A2 (en) 2000-02-08 2001-02-08 G-protein coupled receptor proteins and nucleic acids encoding same

Country Status (2)

Country Link
AU (1) AU2001239756A1 (en)
WO (1) WO2001059113A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0008504D0 (en) * 2000-04-05 2000-05-24 Pfizer Ltd Novel polypeptide
WO2001077149A2 (en) * 2000-04-07 2001-10-18 Bayer Aktiengesellschaft Regulation of human cyslt2-like gpcr protein
US7531310B2 (en) 2000-11-17 2009-05-12 Bristol-Myers Squibb Company Methods of diagnosing Crohn's disease by measuring expression level of RNA encoding human G-protein coupled receptor, HGPRBMY11
US20020155473A1 (en) * 2000-12-22 2002-10-24 Zaoyuan Peng Methods for identifying G-protein coupled receptors associated with diseases
EP1539955A4 (en) * 2001-08-20 2006-09-27 Bristol Myers Squibb Co G-protein coupled receptor polynucleotides and methods of use thereof
WO2003080097A2 (en) * 2002-03-22 2003-10-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with homo sapiens g - protein - coupled receptor 7 (gpr7)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050549A2 (en) * 1997-05-07 1998-11-12 Human Genome Sciences, Inc. Two human g-protein coupled receptors: ebv-induced gpcr 2 (ebi-2) and edg-1-like gpcr
WO1999002675A1 (en) * 1997-07-09 1999-01-21 Euroscreen S.A. G-coupled receptor showing selective affinity for atp
WO1999048921A1 (en) * 1998-03-26 1999-09-30 The Board Of Trustees Of The Leland Stanford Junior University Novel mammalian g-protein coupled receptors having extracellular leucine rich repeat regions
WO2001019986A1 (en) * 1999-09-14 2001-03-22 Yamanouchi Pharmaceutical Co., Ltd. Peptide leukotriene receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001059118A1 (en) * 2000-02-11 2001-08-16 Millennium Pharmaceuticals, Inc. 43239, a gpcr-like molecule and uses thereof
WO2001059105A1 (en) * 2000-02-10 2001-08-16 Glaxo Group Limited Cysteinyl leukotriene receptor 2 (cysl t2)

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050549A2 (en) * 1997-05-07 1998-11-12 Human Genome Sciences, Inc. Two human g-protein coupled receptors: ebv-induced gpcr 2 (ebi-2) and edg-1-like gpcr
WO1999002675A1 (en) * 1997-07-09 1999-01-21 Euroscreen S.A. G-coupled receptor showing selective affinity for atp
WO1999048921A1 (en) * 1998-03-26 1999-09-30 The Board Of Trustees Of The Leland Stanford Junior University Novel mammalian g-protein coupled receptors having extracellular leucine rich repeat regions
WO2001019986A1 (en) * 1999-09-14 2001-03-22 Yamanouchi Pharmaceutical Co., Ltd. Peptide leukotriene receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001059105A1 (en) * 2000-02-10 2001-08-16 Glaxo Group Limited Cysteinyl leukotriene receptor 2 (cysl t2)
WO2001059118A1 (en) * 2000-02-11 2001-08-16 Millennium Pharmaceuticals, Inc. 43239, a gpcr-like molecule and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DUNN M: "Entry/Acc.no. AL137118; Human DNA sequence from clone RP11-108P5 on chromosome 13q14.12-21.1", EMBL SEQUENCE DATABA, 22 January 2000 (2000-01-22), XP002174876 *
HEISE CHRISTOPHER E ET AL: "Characterization of the human cysteinyl leukotriene 2 receptor", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 275, no. 39, 29 September 2000 (2000-09-29), pages 30531 - 30536, XP002171473, ISSN: 0021-9258 *
TAKASAKI J ET AL: "The molecular characterization and tissue distribution of the human cysteinyl leukotriene CysLT2 receptor", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 274, no. 2, 2 August 2000 (2000-08-02), pages 316 - 322, XP002149804, ISSN: 0006-291X *

Also Published As

Publication number Publication date
WO2001059113A2 (en) 2001-08-16
AU2001239756A1 (en) 2001-08-20

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