HK1033955A1 - Human suppressor trna oligonucleotides and methodsof use for same. - Google Patents

Human suppressor trna oligonucleotides and methodsof use for same.

Info

Publication number
HK1033955A1
HK1033955A1 HK01102893A HK01102893A HK1033955A1 HK 1033955 A1 HK1033955 A1 HK 1033955A1 HK 01102893 A HK01102893 A HK 01102893A HK 01102893 A HK01102893 A HK 01102893A HK 1033955 A1 HK1033955 A1 HK 1033955A1
Authority
HK
Hong Kong
Prior art keywords
same
suppressor trna
methodsof
oligonucleotides
human suppressor
Prior art date
Application number
HK01102893A
Other languages
English (en)
Inventor
Rekha G Panchal
Charles J Link Jr
Original Assignee
Human Gene Therapy Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Gene Therapy Res Inst filed Critical Human Gene Therapy Res Inst
Publication of HK1033955A1 publication Critical patent/HK1033955A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04BTRANSMISSION
    • H04B10/00Transmission systems employing electromagnetic waves other than radio-waves, e.g. infrared, visible or ultraviolet light, or employing corpuscular radiation, e.g. quantum communication
    • H04B10/25Arrangements specific to fibre transmission
    • H04B10/2589Bidirectional transmission
    • H04B10/25891Transmission components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/028Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a herpesvirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Electromagnetism (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Biophysics (AREA)
  • Signal Processing (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
HK01102893A 1998-01-14 2001-04-23 Human suppressor trna oligonucleotides and methodsof use for same. HK1033955A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7141698P 1998-01-14 1998-01-14
PCT/US1999/000717 WO1999036519A1 (en) 1998-01-14 1999-01-13 HUMAN SUPPRESSOR tRNA OLIGONUCLEOTIDES AND METHODS OF USE FOR SAME

Publications (1)

Publication Number Publication Date
HK1033955A1 true HK1033955A1 (en) 2001-10-05

Family

ID=22101183

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01102893A HK1033955A1 (en) 1998-01-14 2001-04-23 Human suppressor trna oligonucleotides and methodsof use for same.

Country Status (9)

Country Link
US (2) US6309830B1 (de)
EP (1) EP1045902B1 (de)
JP (1) JP2002508959A (de)
AT (1) ATE299179T1 (de)
AU (1) AU2225199A (de)
CA (1) CA2318374C (de)
DE (1) DE69926052T2 (de)
HK (1) HK1033955A1 (de)
WO (1) WO1999036519A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1045902B1 (de) * 1998-01-14 2005-07-06 Human Gene Therapy Research Institute Menschliche suppressor trna oligonukleotide und verfahren für deren verwendung
CA2340335A1 (en) * 1998-08-20 2000-03-02 Cell Genesys, Inc. Use of suppressor trna's to regulate cytotoxicity during the production of recombinant gene products
WO2003033521A1 (en) * 2001-10-16 2003-04-24 Massachusetts Institute Of Technology Inppressor trna system in mammalian cells for the introduction of unnatural amino acids in polypeptides.
US20050261210A1 (en) * 2004-02-19 2005-11-24 Bhatnagar Rajiv S Nonsense suppressor agents in treatment of cutaneous and gastrointestinal disorders
WO2005086768A2 (en) * 2004-03-11 2005-09-22 Albert Einstein College Of Medicine Of Yeshiva University Enhanced production of functional proteins from defective genes
WO2008064304A2 (en) * 2006-11-22 2008-05-29 Trana Discovery, Inc. Compositions and methods for the identification of inhibitors of protein synthesis
EP2201118B1 (de) * 2007-09-14 2012-04-18 Trana Discovery Zusammensetzungen und verfahren zur identifizierung von inhibitoren einer retrovirusinfektion
WO2010036795A2 (en) * 2008-09-29 2010-04-01 Trana Discovery, Inc. Screening methods for identifying specific staphylococcus aureus inhibitors
CN107177592B (zh) 2016-03-10 2021-03-30 北京大学 抑制性tRNA通读提前终止密码子疾病中的截短蛋白
EP3589751A4 (de) * 2017-03-03 2021-11-17 The Regents of The University of California Rna-targeting von mutationen über suppressor-trnas und deaminasen
BR112020008725A2 (pt) * 2017-11-02 2021-03-30 The Wistar Institute Of Anatomy And Biology Composição para gerar um ou mais rnat editado por anticódon, e, método para tratar uma doença associada a um códon de terminação prematura
US10905778B2 (en) 2018-09-26 2021-02-02 Case Western Reserve University Methods and compositions for treating a premature stop codon-mediated disorder
AU2019350869A1 (en) * 2018-09-26 2021-05-20 Case Western Reserve University Methods and compositions for treating a premature stop codon-mediated disorder
LU101182B1 (en) * 2019-04-11 2020-10-12 Univ Hamburg Synthetic transfer RNA with extended anticodon loop
WO2020208169A1 (en) * 2019-04-11 2020-10-15 Universität Hamburg Synthetic transfer rna with extended anticodon loop
EP4069842A1 (de) 2019-12-02 2022-10-12 Shape Therapeutics Inc. Therapeutisches editieren
WO2022125531A1 (en) * 2020-12-07 2022-06-16 President And Fellows Of Harvard College Methods for making and using genomically recoded cells
WO2023147348A1 (en) * 2022-01-25 2023-08-03 Hc Bioscience, Inc. Universal suppressor trnas and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687737A (en) 1982-11-12 1987-08-18 Massachusetts Institute Of Technology Mammalian suppressor genes
US4970155A (en) * 1983-03-07 1990-11-13 Abbott Laboratories HSV helper virus independent vector
US6111095A (en) * 1995-06-07 2000-08-29 Merck & Co., Inc. Capped synthetic RNA, analogs, and aptamers
EP1045902B1 (de) * 1998-01-14 2005-07-06 Human Gene Therapy Research Institute Menschliche suppressor trna oligonukleotide und verfahren für deren verwendung

Also Published As

Publication number Publication date
CA2318374C (en) 2012-09-04
CA2318374A1 (en) 1999-07-22
AU2225199A (en) 1999-08-02
EP1045902B1 (de) 2005-07-06
DE69926052T2 (de) 2006-04-27
WO1999036519A1 (en) 1999-07-22
US6309830B1 (en) 2001-10-30
US20020156042A1 (en) 2002-10-24
US7029665B2 (en) 2006-04-18
EP1045902A1 (de) 2000-10-25
DE69926052D1 (de) 2005-08-11
JP2002508959A (ja) 2002-03-26
ATE299179T1 (de) 2005-07-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180113