HK1028243A1 - Process of preparing substituted pyrimidinones - Google Patents

Process of preparing substituted pyrimidinones

Info

Publication number
HK1028243A1
HK1028243A1 HK00107424A HK00107424A HK1028243A1 HK 1028243 A1 HK1028243 A1 HK 1028243A1 HK 00107424 A HK00107424 A HK 00107424A HK 00107424 A HK00107424 A HK 00107424A HK 1028243 A1 HK1028243 A1 HK 1028243A1
Authority
HK
Hong Kong
Prior art keywords
preparing substituted
present
substituted pyrimidinones
mixing
base
Prior art date
Application number
HK00107424A
Other languages
English (en)
Inventor
Laurence E Burgess
Kevin Koch
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of HK1028243A1 publication Critical patent/HK1028243A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
HK00107424A 1997-12-04 2000-11-21 Process of preparing substituted pyrimidinones HK1028243A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6751397P 1997-12-04 1997-12-04
US20456998A 1998-12-03 1998-12-03
PCT/US1998/025790 WO1999028303A1 (en) 1997-12-04 1998-12-04 Process of preparing substituted pyrimidinones

Publications (1)

Publication Number Publication Date
HK1028243A1 true HK1028243A1 (en) 2001-02-09

Family

ID=26747950

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00107424A HK1028243A1 (en) 1997-12-04 2000-11-21 Process of preparing substituted pyrimidinones

Country Status (11)

Country Link
EP (1) EP1037881B1 (pt)
JP (1) JP2001524544A (pt)
AT (1) ATE254112T1 (pt)
AU (1) AU1903899A (pt)
CA (1) CA2312338A1 (pt)
DE (1) DE69819774T2 (pt)
DK (1) DK1037881T3 (pt)
ES (1) ES2207024T3 (pt)
HK (1) HK1028243A1 (pt)
PT (1) PT1037881E (pt)
WO (1) WO1999028303A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11993580B1 (en) 2022-12-02 2024-05-28 Neumora Therapeutics, Inc. Methods of treating neurological disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100897A (en) * 1989-08-28 1992-03-31 Merck & Co., Inc. Substituted pyrimidinones as angiotensin ii antagonists
TW229142B (pt) * 1992-04-15 1994-09-01 Nissan Detrochem Corp

Also Published As

Publication number Publication date
JP2001524544A (ja) 2001-12-04
AU1903899A (en) 1999-06-16
EP1037881A1 (en) 2000-09-27
CA2312338A1 (en) 1999-06-10
ATE254112T1 (de) 2003-11-15
PT1037881E (pt) 2004-04-30
DE69819774T2 (de) 2004-09-23
EP1037881B1 (en) 2003-11-12
ES2207024T3 (es) 2004-05-16
WO1999028303A1 (en) 1999-06-10
DK1037881T3 (da) 2004-02-02
DE69819774D1 (de) 2003-12-18

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20081204