HK1027557A1 - Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases - Google Patents
Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseasesInfo
- Publication number
- HK1027557A1 HK1027557A1 HK00106900.6A HK00106900A HK1027557A1 HK 1027557 A1 HK1027557 A1 HK 1027557A1 HK 00106900 A HK00106900 A HK 00106900A HK 1027557 A1 HK1027557 A1 HK 1027557A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- analogues
- treatment
- neurodegenerative diseases
- aryl sulfonamides
- sulfonamides
- Prior art date
Links
- 125000004421 aryl sulphonamide group Chemical group 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
Classifications
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- C07—ORGANIC CHEMISTRY
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- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/90—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. amino-diphenylethers
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- C07C233/00—Carboxylic acid amides
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- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C311/09—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by at least two halogen atoms
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- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/31—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/32—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
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- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/31—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/35—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
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- C07C311/48—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups having nitrogen atoms of sulfonamide groups further bound to another hetero atom
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- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/44—Amides thereof
- C07F9/4461—Amides thereof the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4476—Amides thereof the amide moiety containing a substituent or a structure which is considered as characteristic of aromatic amines (N-C aromatic linkage)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HK08107388.7A HK1112738A1 (en) | 1997-02-21 | 2000-10-30 | Arylsulfonamides and analogues as well as use for the treatment of neuro- degenerative disorders |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19706902 | 1997-02-21 | ||
DE19740785A DE19740785A1 (de) | 1997-02-21 | 1997-09-17 | Arylsulfonamide und Analoga |
PCT/EP1998/000716 WO1998037061A1 (de) | 1997-02-21 | 1998-02-10 | Arylsulfonamide und analoga und ihre verwendung zur behandlung von neurodegenerativen erkrankungen |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1027557A1 true HK1027557A1 (en) | 2001-01-19 |
Family
ID=7821051
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK00106900.6A HK1027557A1 (en) | 1997-02-21 | 2000-10-30 | Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases |
HK06110901A HK1097820A1 (en) | 1997-02-21 | 2000-10-30 | Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases |
HK08107388.7A HK1112738A1 (en) | 1997-02-21 | 2000-10-30 | Arylsulfonamides and analogues as well as use for the treatment of neuro- degenerative disorders |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06110901A HK1097820A1 (en) | 1997-02-21 | 2000-10-30 | Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases |
HK08107388.7A HK1112738A1 (en) | 1997-02-21 | 2000-10-30 | Arylsulfonamides and analogues as well as use for the treatment of neuro- degenerative disorders |
Country Status (9)
Country | Link |
---|---|
KR (1) | KR100546534B1 (zh) |
CN (2) | CN101177385B (zh) |
AR (2) | AR033787A2 (zh) |
CO (1) | CO4930275A1 (zh) |
DE (2) | DE19740785A1 (zh) |
HK (3) | HK1027557A1 (zh) |
PE (1) | PE72299A1 (zh) |
SV (1) | SV1998000023A (zh) |
ZA (1) | ZA981419B (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6500865B1 (en) | 1998-07-31 | 2002-12-31 | Eli Lilly And Company | Sulfonamide derivatives |
HN1998000027A (es) | 1998-08-19 | 1999-06-02 | Bayer Ip Gmbh | Arilsulfonamidas y analagos |
US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
US7067539B2 (en) | 2001-02-08 | 2006-06-27 | Schering Corporation | Cannabinoid receptor ligands |
WO2005037286A1 (en) | 2003-03-25 | 2005-04-28 | Vasopharm Biotech Gmbh | Use of pteridine derivatives for the treatment of increased intracranial pressure and secondary ischemia |
WO2005090297A1 (en) * | 2004-03-19 | 2005-09-29 | Biotie Therapies Corporation | Sulphonamide derivatives |
US8877794B2 (en) * | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
UA112109C2 (uk) | 2012-03-20 | 2016-07-25 | Адамед Сп. З О.О. | Сульфонамідні похідні бензиламіну для лікування захворювань центральної нервової системи (цнс) |
EP3054936B1 (en) | 2013-10-10 | 2023-10-18 | Eastern Virginia Medical School | 4-((2-hydroxy-3-methoxybenzyl)amino) benzenesulfonamide derivatives as 12-lipoxygenase inhibitors |
DK3484528T3 (da) | 2016-07-18 | 2021-02-15 | Janssen Pharmaceutica Nv | Tau-pet-billeddannelsesligander |
US11440898B2 (en) | 2016-12-28 | 2022-09-13 | Minoryx Therapeutics S.L. | Isoquinoline compounds, methods for their preparation, and therapeutic uses thereof in conditions associated with the alteration of the activity of beta galactosidase |
AR128577A1 (es) * | 2022-03-01 | 2024-05-22 | Syngenta Crop Protection Ag | Compuestos herbicidas |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4610829A (en) * | 1968-08-21 | 1986-09-09 | Produits Chimiques Ugine Kuhlmann | Polyfluorinated sulphonic acids and their derivatives |
DE3632329A1 (de) * | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
US4931457B1 (en) * | 1989-06-28 | 1993-11-16 | Hoechst-Roussel Pharmaceuticals Incorporated | Naphthylamino-and naphthyloxy-pyridineamin compounds useful as topical antiinflammatory agents for the treatment of skin disorders |
-
1997
- 1997-09-17 DE DE19740785A patent/DE19740785A1/de not_active Withdrawn
-
1998
- 1998-02-10 CN CN2007101667578A patent/CN101177385B/zh not_active Expired - Fee Related
- 1998-02-10 KR KR1019997007552A patent/KR100546534B1/ko not_active IP Right Cessation
- 1998-02-10 CN CNB2005101041423A patent/CN100371318C/zh not_active Expired - Fee Related
- 1998-02-10 DE DE59806627T patent/DE59806627D1/de not_active Expired - Lifetime
- 1998-02-17 CO CO98008408A patent/CO4930275A1/es unknown
- 1998-02-20 SV SV1998000023A patent/SV1998000023A/es active IP Right Grant
- 1998-02-20 ZA ZA981419A patent/ZA981419B/xx unknown
- 1998-02-20 PE PE1998000123A patent/PE72299A1/es not_active Application Discontinuation
-
1999
- 1999-02-23 AR ARP990100662A patent/AR033787A2/es active IP Right Grant
- 1999-02-23 AR ARP990100663A patent/AR017460A2/es active IP Right Grant
-
2000
- 2000-10-30 HK HK00106900.6A patent/HK1027557A1/xx not_active IP Right Cessation
- 2000-10-30 HK HK06110901A patent/HK1097820A1/xx not_active IP Right Cessation
- 2000-10-30 HK HK08107388.7A patent/HK1112738A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE19740785A1 (de) | 1998-08-27 |
CO4930275A1 (es) | 2000-06-27 |
SV1998000023A (es) | 1999-01-18 |
KR100546534B1 (ko) | 2006-01-26 |
HK1112738A1 (en) | 2008-09-12 |
KR20000075493A (ko) | 2000-12-15 |
ZA981419B (en) | 1998-08-24 |
DE59806627D1 (de) | 2003-01-23 |
CN101177385B (zh) | 2011-06-15 |
HK1097820A1 (en) | 2007-07-06 |
AR033787A2 (es) | 2004-01-07 |
AR017460A2 (es) | 2001-09-05 |
PE72299A1 (es) | 1999-09-24 |
CN1754873A (zh) | 2006-04-05 |
CN100371318C (zh) | 2008-02-27 |
CN101177385A (zh) | 2008-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20140210 |