HK1023725A1 - Treatment of spasticity, convulsions by isovalericacid derivatives cns depressants. - Google Patents

Treatment of spasticity, convulsions by isovalericacid derivatives cns depressants.

Info

Publication number
HK1023725A1
HK1023725A1 HK00102920A HK00102920A HK1023725A1 HK 1023725 A1 HK1023725 A1 HK 1023725A1 HK 00102920 A HK00102920 A HK 00102920A HK 00102920 A HK00102920 A HK 00102920A HK 1023725 A1 HK1023725 A1 HK 1023725A1
Authority
HK
Hong Kong
Prior art keywords
treatment
convulsions
spasticity
isovalericacid
derivatives
Prior art date
Application number
HK00102920A
Other languages
English (en)
Inventor
Linda D Artman
Manuel F Balandrin
Original Assignee
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Pharma Inc filed Critical Nps Pharma Inc
Publication of HK1023725A1 publication Critical patent/HK1023725A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/84—Valerianaceae (Valerian family), e.g. valerian
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Psychology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
HK00102920A 1996-08-30 2000-05-16 Treatment of spasticity, convulsions by isovalericacid derivatives cns depressants. HK1023725A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2505096P 1996-08-30 1996-08-30
PCT/US1997/015272 WO1998008498A1 (en) 1996-08-30 1997-08-29 Treatment of spasticity, convulsions by isovaleric acid derivatives cns depressants

Publications (1)

Publication Number Publication Date
HK1023725A1 true HK1023725A1 (en) 2000-09-22

Family

ID=21823778

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00102920A HK1023725A1 (en) 1996-08-30 2000-05-16 Treatment of spasticity, convulsions by isovalericacid derivatives cns depressants.

Country Status (16)

Country Link
EP (1) EP0938304B1 (ko)
JP (1) JP2000504035A (ko)
KR (1) KR100594400B1 (ko)
CN (2) CN1531924A (ko)
AT (1) ATE284683T1 (ko)
AU (1) AU728765B2 (ko)
BR (1) BR9713188A (ko)
CA (1) CA2264577A1 (ko)
DE (1) DE69731968T2 (ko)
DK (1) DK0938304T3 (ko)
ES (1) ES2235251T3 (ko)
HK (1) HK1023725A1 (ko)
IL (1) IL128724A (ko)
PT (1) PT938304E (ko)
RU (1) RU2232016C2 (ko)
WO (1) WO1998008498A1 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589994B1 (en) 1996-08-30 2003-07-08 Nps Pharmaceuticals, Inc. Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound
EP1576962A1 (en) * 1998-03-04 2005-09-21 Nps Pharmaceuticals, Inc. Composition comprising isovaleramide and ibuprofen
ES2242385T3 (es) * 1998-03-04 2005-11-01 Nps Pharmaceuticals, Inc. Composiciones que incluyen amina isovalerica e ibuprofeno.
AU2003204485B2 (en) * 1998-03-04 2006-06-08 Nps Pharmaceuticals, Inc. Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a nsaid
US6383527B1 (en) * 1999-03-04 2002-05-07 Nps Pharmaceuticals, Inc. Compositions comprising valerian extracts, isovaleric acid or derivatives thereof with a NSAID
US6346283B1 (en) * 1999-03-26 2002-02-12 Ancile Pharmaceuticals Use of valeriana for the treatment of restless leg syndrome and related disorders
US7235258B1 (en) 1999-10-19 2007-06-26 Nps Pharmaceuticals, Inc. Sustained-release formulations for treating CNS-mediated disorders
CA2387819A1 (en) * 1999-10-19 2001-04-26 Nps Pharmaceuticals, Inc. Sustained-release formulations for treating cns-mediated disorders
MXPA03001458A (es) * 2000-08-17 2004-05-04 Teva Pharma Derivados de acido valproico para el tratamiento del dolor.
EP1385520A4 (en) * 2001-02-08 2007-03-21 Nps Pharma Inc METHODS AND COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRICAL DISEASES AND FOR THE IDENTIFICATION OF COMPOUNDS FOR THE TREATMENT THEREOF
WO2003063605A1 (en) * 2002-02-01 2003-08-07 Eugene Science Inc. Chewing gum composition containing plant sterol for decrease of flood cholesterol levels and prevention of periodontal disease
US20060025477A1 (en) * 2004-07-22 2006-02-02 Artman Linda D Analogs of isovaleramide, a pharmaceutical composition including the same, and a method of treating central nervous system conditions or diseases
DE102006062264A1 (de) * 2006-12-22 2008-06-26 Joh. Barth & Sohn Gmbh & Co. Kg Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen
RU2460534C1 (ru) * 2011-04-15 2012-09-10 Учреждение Российская академия наук Сибирское отделение (СО РАН) Институт общей и экспериментальной биологии (ИОЭБ СО РАН) Способ получения средства, обладающего анксиолитической активностью
CN103565959B (zh) * 2013-11-06 2015-04-08 李传平 一种治疗精神分裂症的汤剂
CN103961341B (zh) * 2014-05-30 2015-12-02 杨献华 一种治疗偏头痛的药物组合物及其应用
EP3423433A4 (en) * 2016-02-29 2019-12-25 Bio-Pharm Solutions Co., Ltd. SULFAMATE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
KR102333460B1 (ko) * 2016-11-15 2021-12-15 경희대학교 산학협력단 쥐오줌풀 추출물을 유효성분으로 포함하는 측두엽 뇌전증 예방 또는 치료용 약학적 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617555C3 (de) * 1966-04-19 1974-09-19 Kali-Chemie Ag, 3000 Hannover Verfahren zur Isolierung von therapeutisch wertvollen Isovaleriansäureestern aus Valeriana- und Kentranthus-Extrakten
DE2230626B2 (de) * 1972-06-22 1978-07-20 Roland Dr. 7967 Bad Waldsee Schaette Baldrianpräparat
US5506268A (en) * 1993-06-11 1996-04-09 Nps Pharmaceuticals, Inc. Use of isovaleramide as a mild anxiolytic and sedative agent

Also Published As

Publication number Publication date
BR9713188A (pt) 1999-11-03
EP0938304B1 (en) 2004-12-15
DE69731968D1 (de) 2005-01-20
AU728765B2 (en) 2001-01-18
JP2000504035A (ja) 2000-04-04
EP0938304A1 (en) 1999-09-01
ES2235251T3 (es) 2005-07-01
RU2232016C2 (ru) 2004-07-10
CN1531924A (zh) 2004-09-29
CN1235541A (zh) 1999-11-17
ATE284683T1 (de) 2005-01-15
DK0938304T3 (da) 2005-03-14
WO1998008498A1 (en) 1998-03-05
CN1152677C (zh) 2004-06-09
KR100594400B1 (ko) 2006-07-03
KR20000038194A (ko) 2000-07-05
IL128724A0 (en) 2000-01-31
CA2264577A1 (en) 1998-03-05
DE69731968T2 (de) 2005-12-22
IL128724A (en) 2003-05-29
PT938304E (pt) 2005-04-29
AU4330297A (en) 1998-03-19

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080829