HK1020993A1 - Vectors and methods for tissue specific synthesis of protein in eggs of transgenic hens - Google Patents

Vectors and methods for tissue specific synthesis of protein in eggs of transgenic hens

Info

Publication number
HK1020993A1
HK1020993A1 HK99106142A HK99106142A HK1020993A1 HK 1020993 A1 HK1020993 A1 HK 1020993A1 HK 99106142 A HK99106142 A HK 99106142A HK 99106142 A HK99106142 A HK 99106142A HK 1020993 A1 HK1020993 A1 HK 1020993A1
Authority
HK
Hong Kong
Prior art keywords
eggs
vectors
protein
methods
tissue specific
Prior art date
Application number
HK99106142A
Other languages
English (en)
Inventor
Macarthur C William
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan State filed Critical Univ Michigan State
Publication of HK1020993A1 publication Critical patent/HK1020993A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/20—Animal model comprising regulated expression system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/30—Bird
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
HK99106142A 1996-06-12 1999-12-28 Vectors and methods for tissue specific synthesis of protein in eggs of transgenic hens HK1020993A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1964196P 1996-06-12 1996-06-12
US08/844,175 US6825396B2 (en) 1996-06-12 1997-04-18 Methods for tissue specific synthesis of protein in eggs of transgenic hens
PCT/US1997/009889 WO1997047739A1 (fr) 1996-06-12 1997-06-06 Vecteurs et procedes pour synthese tissulaire propre de proteines dans les oeufs de poules transgeniques

Publications (1)

Publication Number Publication Date
HK1020993A1 true HK1020993A1 (en) 2000-05-26

Family

ID=26692444

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99106142A HK1020993A1 (en) 1996-06-12 1999-12-28 Vectors and methods for tissue specific synthesis of protein in eggs of transgenic hens

Country Status (8)

Country Link
US (5) US6825396B2 (fr)
EP (1) EP0960194A4 (fr)
JP (1) JP2000512149A (fr)
AU (1) AU726386B2 (fr)
CA (1) CA2257871A1 (fr)
HK (1) HK1020993A1 (fr)
NZ (1) NZ333295A (fr)
WO (1) WO1997047739A1 (fr)

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US6825396B2 (en) * 1996-06-12 2004-11-30 Board Of Trustees Operating Michigan State University Methods for tissue specific synthesis of protein in eggs of transgenic hens
US6156569A (en) * 1997-08-04 2000-12-05 University Of Massachusetts Office Of Vice Chancellor For Research At Amherst Prolonged culturing of avian primordial germ cells (PGCs) using specific growth factors, use thereof to produce chimeric avians
US6861572B1 (en) 1997-11-14 2005-03-01 Origen Therapeutics, Inc. Production of proteins in eggs
ATE356878T1 (de) * 1997-08-22 2007-04-15 Univ Guelph Herstellung von proteinen in eiern
US20050114916A1 (en) * 1998-08-21 2005-05-26 Etches Robert J. Production of proteins in eggs
ES2357495T3 (es) * 1997-10-16 2011-04-27 University Of Georgia Research Foundation, Inc. Aves transgénicas y producción de proteína.
US8563803B2 (en) * 1997-10-16 2013-10-22 Synageva Biopharma Corp. Method of making protein in an egg of a transgenic chicken
US7511120B2 (en) * 1997-10-16 2009-03-31 Synageva Biopharma Corp. Glycosylated G-CSF obtained from a transgenic chicken
US20090074718A1 (en) * 1997-10-16 2009-03-19 Ivarie Robert D Avian derived erythropoietin
US7129390B2 (en) * 1997-10-16 2006-10-31 Avigenics, Inc Poultry Derived Glycosylated Interferon Alpha 2b
US20040019923A1 (en) * 1997-10-16 2004-01-29 Ivarie Robert D. Exogenous proteins expressed in avians and their eggs
AU5690799A (en) * 1998-08-25 2000-03-14 Avigenics, Inc. Direct oviduct transgenesis
US7339090B2 (en) 2001-02-13 2008-03-04 Avigenics, Inc. Microinjection devices and methods of use
US7541512B2 (en) * 2001-03-30 2009-06-02 Synageva Biopharma Corp. Avians containing a lysozyme promoter transgene
US7176300B2 (en) 2001-03-30 2007-02-13 Avigenics, Inc. Avian lysozyme promoter
WO2002079447A2 (fr) 2001-03-30 2002-10-10 Avigenics, Inc. Promoteur de lysozymes aviaires
EP1425386A4 (fr) * 2001-08-13 2007-05-02 Embrex Inc Techniques d'injection sur des oeufs aviaires
US7550650B2 (en) 2001-09-18 2009-06-23 Synageva Biopharma Corp. Production of a transgenic avian by cytoplasmic injection
AU2002341746A1 (en) 2001-09-18 2003-04-01 Avigenics, Inc. Production of a transgenic avian by cytoplasmic injection
WO2003024199A2 (fr) * 2001-09-21 2003-03-27 Avigenics, Inc. Production d'oiseaux transgeniques par transfection induite par le sperme
FR2832423B1 (fr) * 2001-11-22 2004-10-08 Vivalis Systeme d'expression de proteines exogenes dans un systeme aviaire
US6875588B2 (en) * 2001-11-30 2005-04-05 Avigenics, Inc. Ovomucoid promoter and methods of use
US20100333219A1 (en) * 2001-11-30 2010-12-30 Synageva Biopharma Corp. Methods of protein production using ovomucoid regulatory regions
US7335761B2 (en) * 2001-11-30 2008-02-26 Avigenics, Inc. Avian gene expression controlling regions
US7294507B2 (en) 2001-11-30 2007-11-13 Avigenics, Inc. Ovomucoid promoters and methods of use
US20040210954A1 (en) * 2003-03-07 2004-10-21 Alex Harvey Integrase mediated avian transgenesis
US7323618B2 (en) * 2002-02-01 2008-01-29 Origen Therapeutics, Inc. Tissue specific expression of exogenous proteins in transgenic chickens
US7135562B2 (en) 2002-03-14 2006-11-14 University Of Cincinnati Avian iFABP gene expression controlling region
US20050246782A1 (en) * 2002-03-22 2005-11-03 Origen Therapeutics Transgenic aves producing human polyclonal antibodies
US20040172667A1 (en) * 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
US7527966B2 (en) * 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
JP2005530516A (ja) * 2002-06-26 2005-10-13 トランスジェンアールエックス，インコーポレイテッド トランスポゾンベースのベクターを使用したトランスジェニック動物における遺伝子調節
DK2314629T4 (da) 2002-07-18 2023-02-06 Merus Nv Rekombinant produktion af blandinger af antistoffer
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
GB0227645D0 (en) * 2002-11-27 2003-01-08 Viragen Inc Protein production in transgenic avians
CN100366738C (zh) * 2002-12-12 2008-02-06 上海复旦新杨生物科技有限责任公司 人瘦素蛋白在鸡蛋蛋清中的特异表达
US7803362B2 (en) * 2003-01-24 2010-09-28 Synageva Biopharma Corp. Glycosylated interferon alpha
EP1623035A4 (fr) * 2003-04-15 2006-08-30 Univ Georgia Res Found Transgenese aviaire utilisant une region du gene de l'ovalbumine du poulet
US7381712B2 (en) * 2003-05-09 2008-06-03 Avigenics, Inc. In vivo transfection in avians
US20080222744A1 (en) * 2003-05-09 2008-09-11 Avigenics, Inc. In vivo transfection in avians
AU2004242614B2 (en) 2003-05-30 2011-09-22 Merus N.V. Fab library for the preparation of anti vegf and anti rabies virus fabs
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
US20050090001A1 (en) 2003-10-07 2005-04-28 Parker Stephen H. Cell lines and methods for producing proteins
WO2005062881A2 (fr) 2003-12-24 2005-07-14 Transgenrx, Inc. Therapie genique faisant intervenir des vecteurs de transposon
ES2380804T3 (es) * 2004-01-08 2012-05-18 Kaneka Corporation Método de construcción de un ave transgénica
ES2646560T3 (es) 2004-01-20 2017-12-14 Merus N.V. Mezclas de proteínas de unión
AU2006210645A1 (en) * 2005-02-01 2006-08-10 Symphogen A/S Transgenic chickens
WO2006112147A1 (fr) * 2005-03-30 2006-10-26 Kaneka Corporation Oiseau transgenique produisant de l’erythropoietine et procede pour l’obtenir
GB2450688A (en) * 2005-05-11 2009-01-07 Viragen Inc Ovalbumin promoter constructs for retroviral vectors
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WO2010036976A2 (fr) 2008-09-25 2010-04-01 Transgenrx, Inc. Nouveaux vecteurs pour la production d'anticorps
EP2342224A2 (fr) * 2008-09-25 2011-07-13 TransGenRx, Inc. Nouveaux vecteurs pour la production d'interféron
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US9150881B2 (en) 2009-04-09 2015-10-06 Proteovec Holding, L.L.C. Production of proteins using transposon-based vectors
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ES2628841T3 (es) 2010-03-12 2017-08-04 Alexion Pharmaceuticals, Inc. Proteínas de fusión npp1
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US6825396B2 (en) * 1996-06-12 2004-11-30 Board Of Trustees Operating Michigan State University Methods for tissue specific synthesis of protein in eggs of transgenic hens

Also Published As

Publication number Publication date
EP0960194A4 (fr) 2004-08-04
NZ333295A (en) 2000-05-26
US20090042299A1 (en) 2009-02-12
US20100330666A1 (en) 2010-12-30
US7378086B2 (en) 2008-05-27
JP2000512149A (ja) 2000-09-19
US20100015699A1 (en) 2010-01-21
AU3479997A (en) 1998-01-07
EP0960194A1 (fr) 1999-12-01
US20050066382A1 (en) 2005-03-24
CA2257871A1 (fr) 1997-12-18
AU726386B2 (en) 2000-11-02
WO1997047739A1 (fr) 1997-12-18
US6825396B2 (en) 2004-11-30
US20030074681A1 (en) 2003-04-17

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20120606