HK1017691A1 - Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2-methyl-5 h-pregna-1,4-dienoÄ17,16-dÜoxazole-3,20-dione - Google Patents

Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2-methyl-5 h-pregna-1,4-dienoÄ17,16-dÜoxazole-3,20-dione

Info

Publication number
HK1017691A1
HK1017691A1 HK99102753A HK99102753A HK1017691A1 HK 1017691 A1 HK1017691 A1 HK 1017691A1 HK 99102753 A HK99102753 A HK 99102753A HK 99102753 A HK99102753 A HK 99102753A HK 1017691 A1 HK1017691 A1 HK 1017691A1
Authority
HK
Hong Kong
Prior art keywords
pregna
dione
methyl
acetyloxy
hydroxy
Prior art date
Application number
HK99102753A
Other languages
English (en)
Inventor
Luigi Forte
Calogero Cancellieri
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HK1017691A1 publication Critical patent/HK1017691A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK99102753A 1995-12-13 1999-06-29 Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2-methyl-5 h-pregna-1,4-dienoÄ17,16-dÜoxazole-3,20-dione HK1017691A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95119626 1995-12-13
PCT/EP1996/005390 WO1997021722A1 (en) 1995-12-13 1996-12-04 PREPARATION OF (11β,16β)-21-(ACETYLOXY)-11-HYDROXY-2'-METHYL-5'H-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE

Publications (1)

Publication Number Publication Date
HK1017691A1 true HK1017691A1 (en) 1999-11-26

Family

ID=8219882

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99102753A HK1017691A1 (en) 1995-12-13 1999-06-29 Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2-methyl-5 h-pregna-1,4-dienoÄ17,16-dÜoxazole-3,20-dione

Country Status (16)

Country Link
US (1) US6103895A (pt)
EP (1) EP0876394B1 (pt)
JP (1) JP4016070B2 (pt)
KR (1) KR100453029B1 (pt)
CN (1) CN100358914C (pt)
AT (1) ATE201213T1 (pt)
AU (1) AU707409B2 (pt)
CA (1) CA2238691C (pt)
DE (1) DE69612871T2 (pt)
DK (1) DK0876394T3 (pt)
ES (1) ES2157476T3 (pt)
GR (1) GR3035988T3 (pt)
HK (1) HK1017691A1 (pt)
PT (1) PT876394E (pt)
WO (1) WO1997021722A1 (pt)
ZA (1) ZA9610412B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100351266C (zh) * 1995-12-13 2007-11-28 赛诺菲·阿温提斯股份公司 (11β，16β)－21－(3－羰基－3－氧代丙氧基) －11－羟基－2′－甲基－5′H－孕甾－1，4－二烯并[17，16－D]唑－3，20－二酮的制备方法
CN106008660B (zh) * 2016-06-20 2018-02-23 湖南科瑞生物制药股份有限公司 地夫可特的制备方法
CN107488203B (zh) * 2017-08-30 2019-06-04 湖南科瑞生物制药股份有限公司 一种16a-羟基泼尼松龙的制备方法
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE250538C (pt) *
DD250538A1 (de) * 1984-12-11 1987-10-14 Jenapharm Veb Verfahren zur selektiven acetylierung von hydroxy-steroidcarbonsaeuren
GB8730216D0 (en) * 1987-12-29 1988-02-03 Lepetit Spa Process for preparation of pregnenooxazolines
CN100351266C (zh) * 1995-12-13 2007-11-28 赛诺菲·阿温提斯股份公司 (11β，16β)－21－(3－羰基－3－氧代丙氧基) －11－羟基－2′－甲基－5′H－孕甾－1，4－二烯并[17，16－D]唑－3，20－二酮的制备方法

Also Published As

Publication number Publication date
DK0876394T3 (da) 2001-08-06
AU707409B2 (en) 1999-07-08
CA2238691A1 (en) 1997-06-19
ZA9610412B (en) 1997-07-23
US6103895A (en) 2000-08-15
EP0876394A1 (en) 1998-11-11
CN100358914C (zh) 2008-01-02
AU1175697A (en) 1997-07-03
ES2157476T3 (es) 2001-08-16
EP0876394B1 (en) 2001-05-16
GR3035988T3 (en) 2001-08-31
KR19990072026A (ko) 1999-09-27
ATE201213T1 (de) 2001-06-15
CN1204339A (zh) 1999-01-06
DE69612871D1 (de) 2001-06-21
CA2238691C (en) 2004-07-20
WO1997021722A1 (en) 1997-06-19
JP4016070B2 (ja) 2007-12-05
PT876394E (pt) 2001-08-30
KR100453029B1 (ko) 2004-12-17
DE69612871T2 (de) 2001-10-04
JP2000503632A (ja) 2000-03-28

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Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20161203