HK1010690A1 - (3R,4r)-delta6 -tetrahydrocannabinol-7-oic acids - Google Patents

(3R,4r)-delta6 -tetrahydrocannabinol-7-oic acids

Info

Publication number
HK1010690A1
HK1010690A1 HK98111583A HK98111583A HK1010690A1 HK 1010690 A1 HK1010690 A1 HK 1010690A1 HK 98111583 A HK98111583 A HK 98111583A HK 98111583 A HK98111583 A HK 98111583A HK 1010690 A1 HK1010690 A1 HK 1010690A1
Authority
HK
Hong Kong
Prior art keywords
delta6
tetrahydrocannabinol
oic acids
oic
acids
Prior art date
Application number
HK98111583A
Other languages
English (en)
Inventor
Raphael Mechoulam
Sumner H Burstein
Original Assignee
Sumner H Burstein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumner H Burstein filed Critical Sumner H Burstein
Publication of HK1010690A1 publication Critical patent/HK1010690A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Tires In General (AREA)
  • Glass Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK98111583A 1992-07-14 1998-10-29 (3R,4r)-delta6 -tetrahydrocannabinol-7-oic acids HK1010690A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/913,096 US5338753A (en) 1992-07-14 1992-07-14 (3R,4R)-Δ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics
PCT/US1993/006580 WO1994001429A1 (en) 1992-07-14 1993-07-13 (3r,4r)-δ6-tetrahydrocannabinol-7-oic acids

Publications (1)

Publication Number Publication Date
HK1010690A1 true HK1010690A1 (en) 1999-06-25

Family

ID=25432922

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98111583A HK1010690A1 (en) 1992-07-14 1998-10-29 (3R,4r)-delta6 -tetrahydrocannabinol-7-oic acids

Country Status (13)

Country Link
US (1) US5338753A (da)
EP (1) EP0650483B1 (da)
JP (1) JP3278159B2 (da)
KR (1) KR100289202B1 (da)
AT (1) ATE183744T1 (da)
AU (1) AU676845B2 (da)
CA (1) CA2140368C (da)
DE (1) DE69326149T2 (da)
DK (1) DK0650483T3 (da)
ES (1) ES2138626T3 (da)
GR (1) GR3031966T3 (da)
HK (1) HK1010690A1 (da)
WO (1) WO1994001429A1 (da)

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US5635530A (en) * 1991-09-12 1997-06-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them
IL115245A (en) 1995-09-11 2002-12-01 Yissum Res Dev Co Tumor necrosis factor inhibiting pharmaceuticals
US6132762A (en) * 1997-05-05 2000-10-17 Cristobal; Walter Transcutaneous application of marijuana
US6162829A (en) * 1997-10-17 2000-12-19 Atlantic Pharmaceuticals, Inc. (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
GB9807639D0 (en) * 1998-04-14 1998-06-10 Kennedy Rheumatology Inst Anti-inflammatory agents
US5847128A (en) * 1998-05-29 1998-12-08 Virginia Commonwealth University Water soluble derivatives of cannabinoids
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
IL145470A0 (en) 1999-03-22 2002-06-30 Immugen Pharmaceuticals Inc Compositions for the treatment of immune diseases
US6448288B1 (en) * 2000-05-17 2002-09-10 University Of Massachusetts Cannabinoid drugs
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US6541510B2 (en) * 2000-09-28 2003-04-01 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US7507767B2 (en) * 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
US20030022938A1 (en) * 2001-06-25 2003-01-30 Burstein Sumner H. N-fatty acid-amino acid conjugates and therapeutic uses
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
AR037352A1 (es) * 2001-11-14 2004-11-03 Schering Corp Compuestos ligandos de los receptores de los cannabinoides, una composicion farmaceutica , y el uso de dichos compuestos para la manufactura de medicamentos
EP2130820A1 (en) 2002-02-19 2009-12-09 Shionogi & Co., Ltd. Antipruritics
US20030232101A1 (en) * 2002-03-18 2003-12-18 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
EP1539693B9 (en) 2002-06-19 2008-10-08 Schering Corporation Cannabinoid receptor agonists
WO2004048322A1 (en) 2002-11-25 2004-06-10 Schering Corporation Cannabinoid receptor ligands
US20040186166A1 (en) * 2002-12-19 2004-09-23 Burstein Sumner H. Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators
AR043633A1 (es) 2003-03-20 2005-08-03 Schering Corp Ligandos de receptores de canabinoides
US6916852B2 (en) * 2003-05-12 2005-07-12 University Of Tennessee Research Foundation Method for regulation of microvascular tone
WO2004100893A2 (en) * 2003-05-12 2004-11-25 Indevus Pharmaceuticals, Inc. Methods for treatment of inflammatory diseases using ct-3 or analogs thereof
US20050046848A1 (en) * 2003-08-26 2005-03-03 Blueshift Biotechnologies, Inc. Time dependent fluorescence measurements
WO2005081801A2 (en) * 2004-02-09 2005-09-09 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
CN101005838A (zh) * 2004-06-22 2007-07-25 先灵公司 大麻素受体配体
JP2008505321A (ja) 2004-07-02 2008-02-21 ブルーシフト・バイオテクノロジーズ・インコーポレーテッド 蛍光体微小環境の探索
US7544714B2 (en) * 2004-07-16 2009-06-09 University Of Massachusetts Lipid-amino acid conjugates and methods of use
WO2006065792A2 (en) * 2004-12-13 2006-06-22 Indevus Pharmaceuticals, Inc. Treatment of interstitial cystitis using cannabinoid analogs
WO2006065793A2 (en) 2004-12-13 2006-06-22 Indevus Pharmaceuticals, Inc. TREATMENT OF INTERSTITIAL CYSTITIS USING (6aR,10aR)-Δ8-TETRAHYDROCANNABINOL-11-OIC ACIDS
EP1889198B1 (en) 2005-04-28 2014-11-26 Proteus Digital Health, Inc. Pharma-informatics system
TWI366460B (en) 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
US20070037873A1 (en) * 2005-08-08 2007-02-15 Zurier Robert B Airway remodeling treatments
NZ567029A (en) * 2005-09-29 2011-09-30 Amr Technology Inc Process for production of delta-9- tetrahydrocannabinol
US20070093519A1 (en) * 2005-10-20 2007-04-26 Indevus Pharmaceuticals, Inc. Anti-emetic uses of cannabinoid analogs
WO2007055806A1 (en) * 2005-10-31 2007-05-18 Indevus Pharmaceuticals, Inc. Anti-emetic uses of (3r,4r)-δ8-tetrahydrocannabinol-11-oic acids
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
EP2427178B1 (en) 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US9066910B2 (en) * 2010-04-15 2015-06-30 Steven Rosenblatt Methods and compositions of cannabis extracts
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP2956133A4 (en) 2013-02-12 2016-12-21 Corbus Pharmaceuticals Inc ULTRAPURIC TETRAHYDROCANNABINOL-11-OIC ACIDS
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
US11202771B2 (en) 2018-01-31 2021-12-21 Treehouse Biotech, Inc. Hemp powder
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
EP4017485A1 (en) 2019-08-22 2022-06-29 EPM Group, Inc. Cannabinoid acid ester compositions and uses thereof
WO2021072325A1 (en) * 2019-10-11 2021-04-15 Corbus Pharmaceuticals, Inc. Compositions of ajulemic acid and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973603A (en) * 1988-06-16 1990-11-27 Sumner Burstein Platelet activating factor antagonist and methods of use therefor
IL99468A (en) * 1991-09-12 1997-09-30 Yissum Res Dev Co (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0650483A1 (en) 1995-05-03
DE69326149D1 (de) 1999-09-30
DE69326149T2 (de) 2000-04-27
AU4675993A (en) 1994-01-31
US5338753A (en) 1994-08-16
CA2140368A1 (en) 1994-01-20
GR3031966T3 (en) 2000-03-31
KR950702549A (ko) 1995-07-29
JPH08500096A (ja) 1996-01-09
ATE183744T1 (de) 1999-09-15
WO1994001429A1 (en) 1994-01-20
DK0650483T3 (da) 2000-03-27
AU676845B2 (en) 1997-03-27
CA2140368C (en) 2004-04-27
EP0650483B1 (en) 1999-08-25
EP0650483A4 (en) 1995-05-10
KR100289202B1 (ko) 2001-05-02
ES2138626T3 (es) 2000-01-16
JP3278159B2 (ja) 2002-04-30

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090713