HK1005864A1 - Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity - Google Patents

Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity

Info

Publication number
HK1005864A1
HK1005864A1 HK98104939A HK98104939A HK1005864A1 HK 1005864 A1 HK1005864 A1 HK 1005864A1 HK 98104939 A HK98104939 A HK 98104939A HK 98104939 A HK98104939 A HK 98104939A HK 1005864 A1 HK1005864 A1 HK 1005864A1
Authority
HK
Hong Kong
Prior art keywords
esters
pharmaceutical compositions
preparation
long
antimycotic activity
Prior art date
Application number
HK98104939A
Other languages
English (en)
Inventor
Mose Santaniello
Maria Ornella Tinti
Domenico Misiti
Piero Foresta
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of HK1005864A1 publication Critical patent/HK1005864A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
HK98104939A 1992-01-16 1998-06-05 Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity HK1005864A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920028A IT1254136B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.

Publications (1)

Publication Number Publication Date
HK1005864A1 true HK1005864A1 (en) 1999-01-29

Family

ID=11400574

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98104939A HK1005864A1 (en) 1992-01-16 1998-06-05 Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity

Country Status (13)

Country Link
US (2) US5519056A (de)
EP (1) EP0552138B1 (de)
JP (1) JP3294652B2 (de)
KR (1) KR100251887B1 (de)
AT (1) ATE151744T1 (de)
CA (1) CA2087084C (de)
DE (1) DE69309725T2 (de)
DK (1) DK0552138T3 (de)
ES (1) ES2101998T3 (de)
GR (1) GR3023163T3 (de)
HK (1) HK1005864A1 (de)
IT (1) IT1254136B (de)
ZA (1) ZA93161B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1258370B (it) * 1992-03-02 1996-02-26 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono.
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
US5741816A (en) * 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
IT1277898B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1283955B1 (it) * 1996-03-20 1998-05-07 Sigma Tau Ind Farmaceuti Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria.
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588443A5 (de) * 1974-09-25 1977-06-15 Lonza Ag
CH596147A5 (de) * 1974-09-25 1978-02-28 Lonza Ag
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1170861B (it) * 1981-03-31 1987-06-03 Sigma Tau Ind Farmaceuti Ester di mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT1191945B (it) * 1986-06-04 1988-03-31 Avantgarde Spa N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1235494B (it) * 1987-12-02 1992-09-04 Avantgarde Spa N-alchilammidi della dl e l(-)carnitina dotate di attivita' antibatterica, procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IT1231944B (it) * 1989-05-05 1992-01-16 Sigma Tau Ind Farmaceuti Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina
IT1240775B (it) * 1990-02-23 1993-12-17 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma.

Also Published As

Publication number Publication date
JP3294652B2 (ja) 2002-06-24
ZA93161B (en) 1993-10-06
ES2101998T3 (es) 1997-07-16
ITRM920028A1 (it) 1993-07-16
DE69309725T2 (de) 1997-07-31
ITRM920028A0 (it) 1992-01-16
ATE151744T1 (de) 1997-05-15
GR3023163T3 (en) 1997-07-30
DE69309725D1 (de) 1997-05-22
KR930016392A (ko) 1993-08-26
KR100251887B1 (ko) 2000-05-01
US5525627A (en) 1996-06-11
CA2087084C (en) 2003-12-23
CA2087084A1 (en) 1993-07-17
DK0552138T3 (da) 1997-10-20
JPH05339219A (ja) 1993-12-21
US5519056A (en) 1996-05-21
EP0552138A2 (de) 1993-07-21
IT1254136B (it) 1995-09-08
EP0552138A3 (en) 1993-10-20
EP0552138B1 (de) 1997-04-16

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110115